Parenchymal calcification is associated with the neurological prognosis in patients with congenital rubella syndrome

2021 ◽  
Author(s):  
Takahiro Namiki ◽  
Chika Takano ◽  
Ryoji Aoki ◽  
Quang Duy Trinh ◽  
Ichiro Morioka ◽  
...  
Keyword(s):  
Congenital Rubella Syndrome ◽  
Congenital Rubella ◽  
Neurological Prognosis

Burden of Congenital Rubella Syndrome (CRS) in Bangladesh: Systematic Review of Existing Literature and Transmission Modelling of Seroprevalence Studies

2020 ◽  
Vol 20 (3) ◽  
pp. 284-290
Author(s):  
Jocelyn Chan ◽  
Yue Wu ◽  
James Wood ◽  
Mohammad Muhit ◽  
Mohammed K. Mahmood ◽  
...  
Keyword(s):  
Systematic Review ◽  
Deterministic Model ◽  
Case Series ◽  
Controlled Vocabulary ◽  
Congenital Rubella Syndrome ◽  
Free Text ◽  
Childbearing Age ◽  
Vaccination Programs ◽  
Congenital Rubella ◽  
The Impact

Background and Objectives: Congenital Rubella Syndrome (CRS) is the leading cause of vaccine-preventable congenital anomalies. Comprehensive country-level data on the burden of CRS in low and middle-income countries, such as Bangladesh, are scarce. This information is essential for assessing the impact of rubella vaccination programs. We aim to systematically review the literature on the epidemiology of CRS and estimate the burden of CRS in Bangladesh. Methods: We conducted a systematic review of existing literature and transmission modelling of seroprevalence studies to estimate the pre-vaccine period burden of CRS in Bangladesh. OVID Medline (1948 – 23 November 2016) and OVID EMBASE (1974 – 23 November 2016) were searched using a combination of the database-specific controlled vocabulary and free text terms. We used an age-stratified deterministic model to estimate the pre-vaccination burden of CRS in Bangladesh. Findings: Ten articles were identified, published between 2000 and 2014, including seven crosssectional studies, two case series and one analytical case-control study. Rubella seropositivity ranged from 47.0% to 86.0% among all age population. Rubella sero–positivity increased with age. Rubella seropositivity among women of childbearing age was 81.0% overall. The estimated incidence of CRS was 0·99 per 1,000 live births, which corresponds to approximately 3,292 CRS cases annually in Bangladesh. Conclusion: The estimated burden of CRS in Bangladesh during the pre-vaccination period was high. This will provide important baseline information to assess the impact and cost-effectiveness of routine rubella immunisation, introduced in 2012 in Bangladesh.

THE EXPANDED CONGENITAL RUBELLA SYNDROME: REPORT OF TWO CASES WITH NEONATAL PURPURA AND REVIEW OF THE RECENT LITERATURE

1967 ◽  
Vol 1 (9) ◽  
pp. 420-425 ◽  
Author(s):  
D. W. O'Gorman Hughes ◽  
R. Parkinson ◽  
John Beveridge ◽  
R. R. Reid ◽  
A. M. Murphy
Keyword(s):  
Recent Literature ◽  
Congenital Rubella Syndrome ◽  
Congenital Rubella ◽  
Syndrome Report

scholarly journals Identification of Ocular and Auditory Manifestations of Congenital Rubella Syndrome in Mbingo

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Imran Jivraj ◽  
Chris J. Rudnisky ◽  
Emmanuel Tambe ◽  
Graham Tipple ◽  
Matthew T. S. Tennant
Keyword(s):  
Hearing Impairment ◽  
Cross Sectional Study ◽  
Normal Hearing ◽  
Congenital Rubella Syndrome ◽  
Congenital Glaucoma ◽  
Fundus Photography ◽  
Igg Antibody ◽  
Case Definitions ◽  
Cross Sectional ◽  
Congenital Rubella

Purpose. Congenital rubella syndrome (CRS) is a global cause of preventable hearing impairment, blindness, and intellectual impairment. The present study sought to identify ocular and auditory manifestations of CRS in school-aged children in Mbingo, Cameroon.Design. Cross sectional study.Subjects. Students at two schools, one for children with hearing impairment, were screened for cataract, congenital glaucoma, and pigmentary retinopathy.Methods. Students underwent seven-field digital fundus photography through a dilated pupil using a Topcon NW200 nonmydriatic camera. Images were assessed by retina specialists in Canada via teleophthalmology. Clinical evidence was integrated to form case definitions for CRS based on Center for Disease Control and Prevention guidelines. Serological evidence of rubella infection was obtained using standardized IgG antibody titers.Main Outcome Measure. Number of probable and suspicious cases of CRS.Results. Between September 2009 and May 2010, 320 students participated. There were 28 (10.2%) probable cases, 104 (37.8%) suspects, and 143 (52.0%) unaffected. Rubella IgG serology was positive in 79 (48.7%) of children with hearing impairment and 11 (7.4%) of children with normal hearing.Conclusions. The present study identified 28 probable cases of CRS. Furthermore, 92.6% of students with normal hearing did not possess rubella IgG antibodies making future cases of CRS likely without intervention.

The Congenital Rubella Syndrome with Virus Recovery

1966 ◽  
Vol 62 (2) ◽  
pp. 222-232 ◽  
Author(s):  
Frederick Hampton Roy ◽  
Federico Fuste ◽  
Roger L. Hiatt ◽  
Alice R. Deutsch ◽  
Sheldon B. Korones
Keyword(s):  
Congenital Rubella Syndrome ◽  
Congenital Rubella ◽  
Virus Recovery

Children at High Risk of Diabetes Mellitus: New York Studies of Families with Diabetes and of Children with Congenital Rubella Syndrome

1988 ◽  
pp. 221-227 ◽  
Author(s):  
Robert C. McEvoy ◽  
Barbara Fedun ◽  
Louis Z. Cooper ◽  
Nancy M. Thomas ◽  
Santiago Rodriguez De Cordoba ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
New York ◽  
High Risk ◽  
Congenital Rubella Syndrome ◽  
Congenital Rubella
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