Antenatal hydronephrosis and fetal urine sampling

2019 ◽  
Vol 60 (1) ◽  
pp. 4-9
Author(s):  
Mehmet Sinan Beksac ◽  
Alp Tuna Beksac ◽  
Atakan Tanacan ◽  
Sezcan Mumusoglu ◽  
Doruk Katlan ◽  
...  
Keyword(s):  
Antenatal Hydronephrosis ◽  
Urine Sampling ◽  
Fetal Urine

PROBLEMS OF THE INFORMATIVE AND THE RELIABILITY OF THE ASSESSMENT OF BIOMARKERS INCLUDED IN THE HORMONAL PROFILE OF THE PATIENT

2019 ◽  
pp. 47-50
Keyword(s):  
Hormonal Profile ◽  
Urine Sampling

The accessible lab diagnostic and expansion of knowledge about the important role of hormones in health regulation lead to the increase of the quantity of lab hormonal tests. Often patients prescribe diagnostic by themselves. Incorrect blood, salvia and urine sampling results in the incorrect diagnostic and treatment. The following article is focused on the rules of sampling for hormonal diagnostic.

Multiple, random spot urine sampling for estimating urinary sodium excretion

2021 ◽  
Author(s):  
Gianluigi Ardissino ◽  
Antonio Vergori ◽  
Cesare Vergori ◽  
Laura Martelli ◽  
Valeria Daccò ◽  
...  
Keyword(s):  
Sodium Excretion ◽  
Urinary Sodium Excretion ◽  
Urinary Sodium ◽  
Spot Urine ◽  
Urine Sampling

scholarly journals Postnatal management of children with antenatal hydronephrosis

2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Mohammed S. ElSheemy
Keyword(s):  
Renal Function ◽  
Urinary Tract Obstruction ◽  
Cost Effective ◽  
Voiding Cystourethrography ◽  
Main Body ◽  
Antenatal Hydronephrosis ◽  
Postnatal Management ◽  
Effective Manner ◽  
Lower Urinary Tract Obstruction

Abstract Background Postnatal management of infants with antenatal hydronephrosis (ANH) is still one of the most controversial issues. The majority of infants with ANH are asymptomatic with only few children who develop renal insufficiency. Thus, the biggest challenge for pediatric urologists is to distinguish children who will require further investigations and possible intervention prior to the development of symptoms, complications or renal damage in a cost effective manner without exposing them to the hazards of unnecessary investigations. Main body In this review article, literature on ANH were reviewed to present the current suggestions, recommendations, guidelines and their rational for postnatal management of ANH. It is agreed that a large portion of infants with ANH will improve; thus, the protocol of management is based mainly on observation and follow-up by ultrasound to detect either resolution, stabilization or worsening of hydronephrosis. The first 2 years of life are critical for this follow-up as the final picture is mostly reached during that period. Advanced imaging using voiding cystourethrography or renal scintigraphy are required for children at risk. Then, surgical intervention is selected only for a subgroup of these infants who showed worsening of hydronephrosis or renal function. Conclusions The protocol of management is based mainly on observation and follow-up by US to detect either resolution, stabilization or worsening of hydronephrosis. Postnatal evaluation should be performed for any neonate with a history ANH at any stage during pregnancy even if it was resolved during third trimester. Exclusion of UTI should be performed by urinalysis for all cases followed by urine culture if indicated. Serum creatinine should be performed especially in patients with bilateral ANH. US is the initial standard diagnostic imaging technique. Other imaging modalities like VCUG and nuclear renal scans may be required according to the results of the US evaluation. The most important items in decision making are the presence of bilateral or unilateral hydronephrosis, presence or absence of hydroureter, presence of lower urinary tract obstruction and degree of hydronephrosis on the initial postnatal US. Then an intervention is selected only for a subgroup of these patients who showed deterioration in renal function or degree of hydronephrosis or were complicated by UTIs. All these recommendations are based on the available literature. However, management of ANH is still a controversial issue due to lack of high evidence-based recommendations. Randomised controlled studies are still needed to provide a high level evidence for different aspects of management.

scholarly journals Concentrations of Seven Phthalate Monoesters in Infants and Toddlers Quantified in Urine Extracted from Diapers

2021 ◽  
Vol 18 (13) ◽  
pp. 6806
Author(s):  
Fiorella Lucarini ◽  
Marc Blanchard ◽  
Tropoja Krasniqi ◽  
Nicolas Duda ◽  
Gaëlle Bailat Rosset ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Young Children ◽  
Sampling Technique ◽  
Gas Chromatography Mass Spectrometry ◽  
Urine Collection ◽  
Infants And Toddlers ◽  
Urine Sampling ◽  
Disposable Diapers ◽  
Children’S Exposure

Carrying out exposure studies on children who are not toilet trained is challenging because of the difficulty of urine sampling. In this study, we optimized a protocol for urine collection from disposable diapers for the analysis of phthalate metabolites. The exposure of Swiss children (n = 113) between 6 months and 3 years of life to seven phthalates was assessed by gas chromatography–mass spectrometry measurements. The study showed limited exposures to phthalates, with only 22% of the samples containing some of the metabolites investigated. The three most frequently detected metabolites were monoethyl phthalate, mono-cyclohexyl phthalate, and mono-benzyl phthalate. We also detected mono-n-octyl phthalate and mono(3,5,5-trimethylhexyl) phthalate, which have rarely been observed in urine from infants and toddlers; therefore, di-n-octyl phthalate and bis(3,5,5-trimethylhexyl) phthalate can be considered as potentially new emerging phthalates. This study presents an initial snapshot of the Swiss children’s exposure to phthalates and provides a promising approach for further phthalate biomonitoring studies on young children using disposable diapers as urine sampling technique.

Determining the Uncertainty of Fetal Urine Production Rate Estimations

2021 ◽  
Author(s):  
Mats Fagerquist ◽  
Andreas Carlsson ◽  
Henrik Imberg ◽  
Hans Bokstrom
Keyword(s):  
Production Rate ◽  
Urine Production ◽  
Fetal Urine

Reliability of Sonography for the Prediction of Vesicoureteral Reflux in Children With Mild Hydronephrosis

2021 ◽  
pp. 875647932199064
Author(s):  
Ehsan Valavi ◽  
Azar Nickavar ◽  
Mohammad Parsamanesh
Keyword(s):  
Vesicoureteral Reflux ◽  
Study Design ◽  
Reliable Method ◽  
Low Grade ◽  
Antenatal Hydronephrosis ◽  
Renal Sonography

Objectives: Postnatal evaluation of vesicoureteral reflux (VUR) remains controversial in patients with antenatal hydronephrosis (HN). The objective of this study was to identify the significance of mild postnatal HN as a marker of VUR and its severity. Materials and Methods: Sonographic findings of 248 children (351 kidneys) with persistent postnatal HN were evaluated for the incidence and severity of primary VUR. Results: The majority of patients had mild (67.8%) HN, followed by moderate (27.6%) and severe (4.6%) HN. VUR was identified in 14.7% of patients with mild HN, 18.5% of patients with moderate HN, and 18.7% of patients with severe HN. About 11.44% of patients with mild HN had low-grade VUR, followed by moderate (45.71 %) and severe grades (42.85%). Conclusion: A large number (89%) of patients with mild HN had moderate to severe VUR. In this cohort, renal sonography was not a reliable method for the prediction of VUR and its severity in patients with mild postnatal HN. However, it was reliable for high grades of VUR. These results are limited due to the study design and the inability to generalize these findings. These results should be replicated across other multiple clinics, thereby recruiting more variety of patients, to validate these study recommendations.

Sign in / Sign up

Export Citation Format

Share Document