Fasting plasma glucose variability is an independent risk factor for diabetic retinopathy and diabetic macular oedema in type 2 diabetes: An 8‐year prospective cohort study

2020 ◽  
Vol 48 (4) ◽  
pp. 470-476
Author(s):  
Yi‐Ting Hsieh ◽  
Ming‐Chia Hsieh
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Risk Factor ◽  
Cohort Study ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Independent Risk Factor ◽  
Diabetic Macular Oedema ◽  
Glucose Variability

scholarly journals Impact of Visit-to-Visit Fasting Plasma Glucose Variability on the Development of Type 2 Diabetes: A Nationwide Population-Based Cohort Study

Diabetes Care ◽  
2018 ◽  
Vol 41 (12) ◽  
pp. 2610-2616 ◽  
Author(s):  
Jung A. Kim ◽  
Ji Sung Lee ◽  
Hye Soo Chung ◽  
Eun Roh ◽  
You-Bin Lee ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glucose Variability ◽  
Population Based ◽  
Fasting Plasma

Trajectories of fasting plasma glucose variability and mortality in type 2 diabetes

2018 ◽  
Vol 44 (2) ◽  
pp. 121-128 ◽  
Author(s):  
Chia-Lin Lee ◽  
Wayne Huey-Herng Sheu ◽  
I-Te Lee ◽  
Shih-Yi Lin ◽  
Wen-Miin Liang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Glucose Variability ◽  
Fasting Plasma

Low bilirubin levels are an independent risk factor for diabetic retinopathy and nephropathy in Japanese patients with type 2 diabetes

2015 ◽  
Vol 41 (5) ◽  
pp. 429-431 ◽  
Author(s):  
S. Hamamoto ◽  
H. Kaneto ◽  
S. Kamei ◽  
M. Shimoda ◽  
K. Tawaramoto ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Japanese Patients

scholarly journals Change in fasting plasma glucose and incident type 2 diabetes mellitus: results from a prospective cohort study

BMJ Open ◽  
2016 ◽  
Vol 6 (5) ◽  
pp. e010889 ◽  
Author(s):  
Amirhossein Mozaffary ◽  
Samaneh Asgari ◽  
Maryam Tohidi ◽  
Sara Kazempour-Ardebili ◽  
Fereidoun Azizi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Prospective Cohort ◽  
Incident Type ◽  
Incident Type 2 Diabetes

scholarly journals Serum Antithyroglobulin Antibody Levels Are Associated with Diabetic Retinopathy among Euthyroid Type 2 Diabetes Patients: A Hospital-Based, Retrospective Study

2022 ◽  
Vol 2022 ◽  
pp. 1-10
Author(s):  
Xiaotong Gao ◽  
Xichang Wang ◽  
Yifan Zhong ◽  
Lei Liu ◽  
Weiping Teng ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Reference Interval ◽  
Free Triiodothyronine ◽  
Thyroglobulin Antibody ◽  
Fundus Photographs ◽  
Antibody Levels

Background. Previous studies have revealed that the variation of thyroid indicators may be associated with the risk of diabetic retinopathy (DR) among euthyroid type 2 diabetes (T2D) patients. But the specific conclusions are currently inconsistent. Methods. This is a hospital-based retrospective survey. We recruited 1,145 euthyroid T2D patients and checked the thyroid function and fundus photographs. The modified Airlie House classification system was used to categorize the stages of DR. The association between thyroid indicators and different stages of DR was analyzed. Results. We divided free triiodothyronine (FT3) into tertiles and found that the prevalence of mild nonproliferative DR (NPDR) was significantly higher in T2, compared with T1 (32.0% vs. 25.2%, p < 0.05 ). When FT3 was within the level of T2, FT3 could be an independent risk factor for mild NPDR (OR 1.426, 95% CI (1.031, 1.971), p < 0.05 ). In addition, the prevalence of severe NPDR and proliferative DR (PDR) was significantly higher in thyroglobulin antibody (TgAb) positive group (8.8% vs. 4.1%, p < 0.05 ) and vice versa (33.3% vs. 18.4%, p < 0.05 ). TgAb positivity was also an independent risk factor for severe NPDR and PDR (OR 2.212, 95% CI (1.244, 3.934), p < 0.05 ). Conclusions. We hardly observed a significant change in DR risk with the elevation or reduction of serum TSH or thyroid hormone within the reference interval. Although the slightly elevated FT3 may be associated to mild NPDR, the extensibility of this result remains to be seen. For T2D patients with euthyroid function, there may be a significant correlation between serum TgAb positivity and severe NPDR and PDR.

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