Long-term efficacy and safety of botulinum toxin A injections to treat blepharospasm and hemifacial spasm

2013 ◽  
Vol 42 (3) ◽  
pp. 254-261 ◽  
Author(s):  
Osama H Ababneh ◽  
Altug Cetinkaya ◽  
Dwight R Kulwin
Keyword(s):  
Botulinum Toxin ◽  
Hemifacial Spasm ◽  
Botulinum Toxin A ◽  
Efficacy And Safety ◽  
Toxin A ◽  
Term Efficacy

Long-term efficacy of botulinum toxin A in treatment of various movement disorders over a 10-year period

2002 ◽  
Vol 17 (6) ◽  
pp. 1288-1293 ◽  
Author(s):  
G-Y.R. Hsiung ◽  
S.K. Das ◽  
R. Ranawaya ◽  
A.-L. Lafontaine ◽  
O. Suchowersky
Keyword(s):  
Botulinum Toxin ◽  
Movement Disorders ◽  
Botulinum Toxin A ◽  
Toxin A ◽  
Term Efficacy

scholarly journals Fissurectomy combined with botulinum toxin A: a review of short- and long-term efficacy of this treatment strategy for chronic anal fissure; a consecutive proposal of a treatment algorithm for chronic anal fissure

2020 ◽  
Vol 42 (5) ◽  
pp. 400-408
Author(s):  
M. Trzpis ◽  
J. M. Klaase ◽  
R. H. Koop ◽  
P. M. A. Broens
Keyword(s):  
Botulinum Toxin ◽  
Anal Fissure ◽  
Recurrence Rate ◽  
Treatment Strategy ◽  
Chronic Anal Fissure ◽  
Botulinum Toxin A ◽  
Toxin A ◽  
Term Efficacy ◽  
Short And Long Term

Abstract Background Several studies have investigated the short- and long-term efficacy of fissurectomy combined with botulinum toxin A injection for patients with chronic anal fissure. Objective To evaluate the short- and long-term efficacy of the combined treatment strategy of fissurectomy with botulinum toxin A for chronic anal fissure and to discuss recurrence rates in the light of current theory on the aetiology of anal fissure. Materials and methods This is a narrative review. We conducted an article search using PubMed and calculated the means of the reported efficacy ranges. Results Fissurectomy combined with botulinum toxin A injections freed at least 78% of the patients from symptoms and yielded a fissure healing rate of up to 86%. Within 12 months after treatment a 3% recurrence rate was reported. On average, the long-term recurrence rate was 22%. One study reported a 50% recurrence rate 22 months after treatment. Conclusion The efficacy of fissurectomy combined with botulinum toxin A injection for chronic anal fissure is high. The short-term recurrence rate is low, while long-term recurrence is relatively high. Extended follow-up indicates that recurrence of chronic anal fissure is possibly caused by anal basal pressure building up steadily once again. If so, the cause of renewed increase of pressure should be addressed. Based on the literature and on our clinical experience, we assume that the underlying cause of increasing anal basal pressure is that patients use their pelvic floor muscles inadequately and this in turn leads to chronic anal fissure.

Long-term efficacy of single botulinum toxin-A injection in a relapsing Piriformis syndrome case

2021 ◽  
Vol 429 ◽  
pp. 118631
Author(s):  
Yusak Siahaan ◽  
Amanda Tanasia ◽  
Pamela Tiffani ◽  
Vinson Hartoyo
Keyword(s):  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Piriformis Syndrome ◽  
Toxin A ◽  
Term Efficacy

Long-term efficacy and respective potencies of botulinum toxin A and B: a randomized, double-blind study

2010 ◽  
Vol 164 (1) ◽  
pp. 176-181 ◽  
Author(s):  
G. Kranz ◽  
A. Paul ◽  
B. Voller ◽  
M. Posch ◽  
C. Windischberger ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Blind Study ◽  
Double Blind Study ◽  
Toxin A ◽  
Double Blind ◽  
Term Efficacy

Treatment of spasticity of different origins with botulinum toxin A: long-term results

2008 ◽  
Vol 35 (S 01) ◽  
Author(s):  
K Kollewe ◽  
S Baloush ◽  
K Krampfl ◽  
H Bigalke ◽  
R Dengler ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Long Term Results ◽  
Toxin A ◽  
Different Origins
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