scholarly journals Association of cognitive impairment with magnetic resonance imaging findings and social activities in patients with multiple sclerosis

2014 ◽  
Vol 5 (3) ◽  
pp. 328-335 ◽  
Author(s):  
Masaaki Niino ◽  
Nobuhiro Mifune ◽  
Tatsuo Kohriyama ◽  
Masahiro Mori ◽  
Takashi Ohashi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Magnetic Resonance ◽  
Social Activities ◽  
Imaging Findings ◽  
Resonance Imaging

Cognition with magnetic resonance imaging findings and social activities in patients with multiple sclerosis in a Japanese cohort

2018 ◽  
Vol 10 (1) ◽  
pp. 41-48
Author(s):  
Masaaki Niino ◽  
Toshiyuki Fukazawa ◽  
Jun‐ichi Kira ◽  
Tatsusada Okuno ◽  
Masahiro Mori ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Social Activities ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Japanese Cohort

Multiple Sclerosis and Cognitive Impairment

2021 ◽  
pp. 39-41
Author(s):  
Cristina Valencia-Sanchez ◽  
Jonathan L. Carter
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Information Processing ◽  
Magnetic Resonance ◽  
Processing Speed ◽  
Rehabilitation Program ◽  
Resonance Imaging ◽  
The Past ◽  
Demyelinating Lesions

A 60-year-old woman with a history of multiple sclerosis was evaluated for cognitive concerns. At age 30 years she had an episode of optic neuritis, followed by an episode of bilateral lower extremity numbness at age 35 years. In the following years, she had at least 6 further multiple sclerosis relapses, the last one approximately 3 years before the current presentation. She was initially treated with interferon, but she did not tolerate it. She had been taking glatiramer acetate for the past 3 years. She had noticed progressive deterioration of her gait for the past 3 years, having to use a cane on occasions. Magnetic resonance imaging of the brain showed multiple demyelinating lesions), and magnetic resonance imaging of the cervical spine showed 1 small demyelinating lesion at C6. Vitamin B12 level and thyroid function were normal. Comprehensive neuropsychological testing showed multidomain cognitive impairment, mainly impairment of speed of information processing, spatial discrimination skills, and attention/concentration. The patient’s multiple sclerosis phenotype was consistent with secondary progressive multiple sclerosis. Her cognitive impairment profile, mainly affecting information processing speed and disinhibition suggestive of frontal dysfunction, was consistent with multiple sclerosis. The patient began a cognitive rehabilitation program, and learning and memory aids were recommended. Lifestyle changes were also recommended, including weight loss and physical exercise. She was given recommendations for sleep hygiene and began taking gabapentin for neuropathic pain and restless legs. Cognitive impairment is common in patients with multiple sclerosis. Slowed cognitive processing speed and episodic memory decline are the most common cognitive deficits in MS, with additional difficulties in executive function, verbal fluency, and visuospatial analysis.

THE CORRELATION OF URODYNAMIC FINDINGS WITH CRANIAL MAGNETIC RESONANCE IMAGING FINDINGS IN MULTIPLE SCLEROSIS

1998 ◽  
Vol 159 (3) ◽  
pp. 972-976 ◽  
Author(s):  
YOUNG H. KIM ◽  
CHAD GOODMAN ◽  
ELAN OMESSI ◽  
VICTOR RIVERA ◽  
MICHAEL W. KATTAN ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Cranial Magnetic Resonance Imaging

Diagnosis of Multiple Sclerosis

2016 ◽  
Author(s):  
Loren A. Rolak
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Imaging Study ◽  
Progressive Multiple Sclerosis ◽  
Primary Progressive Multiple Sclerosis ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Mcdonald Criteria ◽  
Highly Sensitive

Because no laboratory test or imaging study is both highly sensitive and highly specific for multiple sclerosis, some uncertainty often accompanies the diagnosis. Various guidelines have been developed to assist the clinician, including the much-modified and commonly used McDonald criteria. Typical features of the history, the physical examination, and magnetic resonance imaging findings usually allow for a secure diagnosis. However, limitations inherent in any testing modality still pose challenges. This is especially true for diagnosis of primary progressive multiple sclerosis because the sensitivity and specificity of the evaluations are lower.

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