Longitudinal changes in plasma sex hormone concentrations correlate with changes in CT‐measured regional adiposity among Japanese American men over 10 years

2020 ◽  
Vol 93 (5) ◽  
pp. 555-563 ◽  
Author(s):  
Kathryn T. Dinh ◽  
John K. Amory ◽  
Alvin M. Matsumoto ◽  
Brett T. Marck ◽  
Wilfred Y. Fujimoto ◽  
...  
Keyword(s):  
Sex Hormone ◽  
Japanese American ◽  
Longitudinal Changes ◽  
Regional Adiposity

Longitudinal changes in sex hormone-binding globulin in men with HIV

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jenny Pena Dias ◽  
Sabina A Haberlen ◽  
Adrian S Dobs ◽  
Jordan E Lake ◽  
Frank J. Palella ◽  
...  
Keyword(s):  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Longitudinal Changes

Longitudinal changes in offspring body weight, fat mass and sex hormone levels according to maternal bisphenol A exposure during gestation and lactation

2013 ◽  
Vol 9 (3) ◽  
pp. 285-293 ◽  
Author(s):  
Hye Ah Lee ◽  
Jung A. Shin ◽  
Byeou Ree Oh ◽  
Sunny Park ◽  
Eurim Jeong ◽  
...  
Keyword(s):  
Body Weight ◽  
Bisphenol A ◽  
Fat Mass ◽  
Sex Hormone ◽  
Longitudinal Changes ◽  
Hormone Levels

1449-P: Longitudinal Changes in Sex Hormone Binding Globulin (SHBG) and Risk of Diabetes: The Study of Women's Health Across the Nation (SWAN)

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1449-P
Author(s):  
MONIQUE M. HEDDERSON ◽  
CATHERINE LEE ◽  
ANGELA CAPRA ◽  
JENNIFER LEE ◽  
PO-YIN CHANG ◽  
...  
Keyword(s):  
Women’S Health ◽  
Women's Health ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Longitudinal Changes

Longitudinal changes in serum testosterone and sex hormone‐binding globulin in men aged 40–69 years from the UK Biobank

2021 ◽  
Author(s):  
Ross J. Marriott ◽  
Kevin Murray ◽  
Graeme J. Hankey ◽  
Laurens Manning ◽  
Girish Dwivedi ◽  
...  
Keyword(s):  
Serum Testosterone ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Uk Biobank ◽  
Hormone Binding ◽  
Longitudinal Changes ◽  
The Uk

scholarly journals Plasma sex hormone concentrations and breast cancer risk in an ethnically diverse population of postmenopausal women: the Multiethnic Cohort Study

2010 ◽  
Vol 17 (1) ◽  
pp. 125-134 ◽  
Author(s):  
Christy G Woolcott ◽  
Yurii B Shvetsov ◽  
Frank Z Stanczyk ◽  
Lynne R Wilkens ◽  
Kami K White ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Postmenopausal Women ◽  
Sex Hormones ◽  
Ethnically Diverse ◽  
Sex Hormone ◽  
Japanese American ◽  
Diverse Population ◽  
Multiethnic Cohort

To add to the existing evidence that comes mostly from White populations, we conducted a nested case–control study to examine the association between sex hormones and breast cancer risk within the Multiethnic Cohort that includes Japanese American, White, Native Hawaiian, African American, and Latina women. Of the postmenopausal women for whom we had a plasma sample, 132 developed breast cancer during follow-up. Two controls per case, matched on study area (Hawaii, Los Angeles), ethnicity/race, birth year, date and time of blood draw and time fasting, were randomly selected from the women who had not developed breast cancer. Levels of estradiol (E2), estrone (E1), androstenedione, dehydroepiandrosterone (DHEA), and testosterone were quantified by RIA after organic extraction and Celite column partition chromatography. E1 sulfate, DHEA sulfate (DHEAS), and sex hormone-binding globulin (SHBG) were quantified by direct immunoassays. Based on conditional logistic regression, the sex hormones were positively associated and SHBG was negatively associated with breast cancer risk. All associations, except those with DHEAS and testosterone showed a significant linear trend. The odds ratio (OR) associated with a doubling of E2 levels was 2.26 (95% confidence interval (CI) 1.58–3.25), and the OR associated with a doubling of testosterone levels was 1.34 (95% CI 0.98–1.82). The associations in Japanese American women, who constituted 54% of our sample, were similar to or nonsignificantly stronger than in the overall group. This study provides the best evidence to date that the association between sex hormones and breast cancer risk is generalizable to an ethnically diverse population.

Longitudinal Changes in Individual BrainAGE in Healthy Aging, Mild Cognitive Impairment, and Alzheimer’s Disease

GeroPsych ◽  
2012 ◽  
Vol 25 (4) ◽  
pp. 235-245 ◽  
Author(s):  
Katja Franke ◽  
Christian Gaser
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Healthy Aging ◽  
Brain Aging ◽  
Elderly Subjects ◽  
Additional Increase ◽  
Longitudinal Changes ◽  
Novel Method ◽  
The Brain

We recently proposed a novel method that aggregates the multidimensional aging pattern across the brain to a single value. This method proved to provide stable and reliable estimates of brain aging – even across different scanners. While investigating longitudinal changes in BrainAGE in about 400 elderly subjects, we discovered that patients with Alzheimer’s disease and subjects who had converted to AD within 3 years showed accelerated brain atrophy by +6 years at baseline. An additional increase in BrainAGE accumulated to a score of about +9 years during follow-up. Accelerated brain aging was related to prospective cognitive decline and disease severity. In conclusion, the BrainAGE framework indicates discrepancies in brain aging and could thus serve as an indicator for cognitive functioning in the future.

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