Urinary iodine excretion (UIE) estimated by iodine/creatinine ratio from spot urine in Chinese school-age children

2016 ◽  
Vol 86 (4) ◽  
pp. 628-633 ◽  
Author(s):  
Wen Chen ◽  
Xiang Li ◽  
Xiaohui Guo ◽  
Jun Shen ◽  
Long Tan ◽  
...  
Keyword(s):  
Urinary Iodine ◽  
School Age Children ◽  
Urinary Iodine Excretion ◽  
School Age ◽  
Creatinine Ratio ◽  
Spot Urine ◽  
Iodine Excretion ◽  
Chinese School

scholarly journals Status iodium pada anak usia sekolah berdasarkan ekskresi iodium urin dan asupan iodium

2019 ◽  
Vol 15 (4) ◽  
pp. 146
Author(s):  
Widya Ayu Kurnia Putri ◽  
Dodik Briawan ◽  
Hidayat Syarief ◽  
Leily Amelia
Keyword(s):  
Pearson Correlation ◽  
Daily Intake ◽  
Urinary Iodine ◽  
Iodine Intake ◽  
School Age Children ◽  
Urinary Iodine Excretion ◽  
School Age ◽  
School Students ◽  
Iodine Status ◽  
Iodine Excretion

Iodine status in school-age children determined from iodine urine excretion and iodine intakeBackground: School-age children are more at risk if they experience deficiencies and excess iodine. The concentration of iodine in urine is a good biomarker for assessing iodine intake, 90% of iodine intake will be excreted through urine. Objective: This study aimed to analyze the iodine status of school-age children based on urinary iodine excretion (UIE) and iodine intake.Method: The study design used a cross-sectional study on 44 healthy school-aged children in Bogor Regency. Subject selection was done purposively in healthy 5th-grade elementary school students. The data taken in this study was urine iodine excretion concentration and food recall (1x24 hours). Data were analyzed using descriptive analysis and Pearson correlation test.Results: Median iodine excretion concentration in urine was 157 μg/l and the average daily iodine intake of children was 83.29 mg/day. Conclusion: The concentration of iodine excretion in the urine of the children is in the category of sufficient iodine as recommended by WHO / UNICEF / ICCID while the daily intake of iodine for children is still in the less category. The results showed that there was no association of iodine daily intake with iodine excretion concentration in urine(p=0.469).

scholarly journals Urinary iodine excretion and thyroid function status in school age children of hilly and plain regions of Eastern Nepal

2015 ◽  
Vol 8 (1) ◽  
Author(s):  
Prem Raj Shakya ◽  
Basanta Gelal ◽  
Binod Kumar Lal Das ◽  
Madhab Lamsal ◽  
Paras Kumar Pokharel ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Urinary Iodine ◽  
School Age Children ◽  
Urinary Iodine Excretion ◽  
School Age ◽  
Iodine Excretion

scholarly journals State of iodine supply of children with chronic somatic diseases

2021 ◽  
pp. 13-18
Author(s):  
N.S. Shevchenko ◽  
◽  
H.О. Shlieienkova ◽  
K.V. Voloshyn ◽  
T.V. Zimnytska ◽  
...  
Keyword(s):  
Iodine Deficiency ◽  
Urinary Iodine ◽  
School Age Children ◽  
Urinary Iodine Excretion ◽  
Urinary Iodine Concentration ◽  
School Age ◽  
Digestive Diseases ◽  
Iodine Supply ◽  
Iodine Excretion ◽  
Somatic Diseases

One of the most common conditions resulting from micronutrient deficiency is iodine deficiency. Purpose — to evaluate the current state of iodine supply in schoolchildren living in the North-Eastern region of Ukraine, including children with digestive diseases and inflammatory joint diseases. Materials and methods. Target group: 86 people (11.8±2.71 years), which included patients with digestive diseases (DD) (26.7%) and juvenile idiopathic arthritis (JIA) (60.5%). Methods: dietary iodine intake evaluation by urinary iodine concentration (Sandell–Kolthoff reaction), followed by calculation of the median. Results. Median urinary iodine excretion was at the lower normal range and amounted to 104.98 μg/l [QR: 59.8; 180.1] in the examined children. Only 51.2% of children had adequate iodine provision; mild iodine deficiency (ID) was diagnosed in 29.1% (Ме=81,91μg/l [QR: 64.26; 90.58]); moderate — 17.4% (Ме=36,19 μg/l [QR: 33.54; 42.24]); severe — in 2.3% of the surveyed (Ме 14,02 μg/l [QR: 12.34; 15.70]). The median urinary iodine excretion in children with somatic diseases was significantly lower than in children of the control group and amounted to 97.26 μg/l [QR 53.7; 148.3] versus 183.71 μg/l [QR 104.4; 287.4], (p=0.003). Conclusions. School-age children have a high incidence of iodine deficiency (51.2%). Often encountered in childhood diseases (DD and JIA) are accompanied by insufficiency of iodine supply. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local Ethics Committee of all participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the author. Key words: iodine deficiency, school-age children, the level of iodine excretion.

Nativer 99mTc-Uptake in der Differentialdiagnostik von unauffälliger Schilddrüse, Struma mit Euthyreose und Schilddrüsenautonomie in einem Jodmangelgebiet

1990 ◽  
Vol 29 (03) ◽  
pp. 113-119
Author(s):  
C. R. Pickardt ◽  
K. Horn ◽  
G. Bechtner ◽  
C. Vaitl ◽  
C. M. Kirsch ◽  
...  
Keyword(s):  
Urinary Iodine ◽  
Inverse Correlation ◽  
Iodine Concentration ◽  
Urinary Iodine Excretion ◽  
Large Scatter ◽  
Spot Urine ◽  
Iodine Supply ◽  
Iodine Contamination ◽  
Iodine Excretion ◽  
Overt Hyperthyroidism

Global TcTU was determined in 568 patients without any specific thyroid drug intake - 54 with normal thyroid, 274 with goitre and euthyroidism and 240 with thyroid autonomy. 57 patients with autonomy and overt hyperthyroidism were the only group with TcTU values significantly higher than normals. Common to all groups was a large scatter of the TcTU values. In 332, the effects of individual iodine supply were studied by measuring the iodine concentration in spot urine samples. There was a significant inverse correlation between the TcTU values and the urinary iodine excretion in the groups of normal thyroids and of goitres with euthyroidism. In the group with autonomy an effect of iodine supply could only be seen in cases of greatly increased urinary iodine excretion, resulting in very low TcTU values. Out of 20 patients with autonomy and iodine contamination, only 4 showed overt hyperthyroidism. The large scatter of TcTU values in all groups may be explained by the persistent iodine deficiency as well as by the frequent exposure to unknown amounts of iodine in patients with thyroid disease. Therefore, the spontaneous TcTU alone cannot identify a small group of patients with autonomy and high risk of iodine-induced hyperthyroidism, from a very large group of patients with goitre.

scholarly journals Nationwide Representative Survey of Dietary Iodine Intake and Urinary Excretion in Postpartum Korean Women

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3955
Author(s):  
Do-Kyung Lee ◽  
Hunjoo Lee ◽  
Hyeyoung Lee ◽  
Taehyung Yoon ◽  
Seon-Joo Park ◽  
...  
Keyword(s):  
Large Scale ◽  
Urinary Iodine ◽  
Brown Seaweed ◽  
Nationwide Survey ◽  
Iodine Intake ◽  
Urinary Iodine Excretion ◽  
Korean Women ◽  
Spot Urine ◽  
Before And After ◽  
Iodine Excretion

Iodine is an essential component of thyroid hormones, but excessive iodine intake can lead to thyroid dysfunction. Traditionally, Korean mothers consume brown seaweed soup (miyeokguk), a high source of iodine, after childbirth. There is controversy regarding the effects of excessive postpartum iodine intake on the health of mothers and infants. Thus far, there have been no nationwide large-scale surveys regarding the status of iodine intake among postpartum women in Korea. Therefore, we conducted a nationwide survey of postpartum dietary iodine intake among Korean women. In total, 1054 Korean women aged ≥19 years, at less than 8 weeks postpartum, participated in this survey. Dietary data were collected using self-reported 2-day dietary records, along with before-and-after meal photos. To evaluate the correlation between dietary iodine and urinary iodine excretion (UIE), spot urine, and 24 h urine samples were collected from 98 and 29 participants, respectively. The mean daily iodine intake among all participants was 2945.6 μg, and it gradually decreased over time after childbirth. Dietary iodine intake was significantly correlated with 24 h UIE (r = 0.396, p < 0.05) and spot urine UIE (r = 0.312, p < 0.05). Follow-up studies are required to examine the influence of excessive postpartum iodine intake on thyroid health in mothers and their infants.

scholarly journals Reliability of studies of iodine intake and recommendations for number of samples in groups and in individuals

2007 ◽  
Vol 99 (4) ◽  
pp. 813-818 ◽  
Author(s):  
Stig Andersen ◽  
Jesper Karmisholt ◽  
Klaus M. Pedersen ◽  
Peter Laurberg
Keyword(s):  
Standard Deviation ◽  
Urinary Iodine ◽  
Iodine Intake ◽  
Urine Samples ◽  
Urinary Iodine Excretion ◽  
Iodine Nutrition ◽  
Cross Sectional ◽  
Spot Urine ◽  
Iodine Excretion ◽  
And Gender

The iodine intake level in a population is determined in cross-sectional studies. Urinary iodine varies considerably and the reliability of studies of iodine nutrition and the number of samples needed is unsettled. We performed a longitudinal study of sixteen healthy men living in an area of mild to moderate iodine deficiency. Iodine and creatinine concentrations were measured in spot urine samples collected monthly for 13 months. From these data we calculated the number of urine samples needed to determine the iodine excretion level for crude urinary iodine and for 24 h iodine excretion estimated from age- and gender-specific creatinine excretions. We found that mean urinary iodine excretion varied from 30 to 87 μg/l (31 to 91 μg/24 h). Sample iodine varied from 10 to 260 μg/l (20 to 161 μg/24 h). Crude urinary iodine varied more than estimated 24 h iodine excretion (population standard deviation 32v. 26; individual standard deviation 29v. 21; Bartlett's test,P < 0·01 for both). The number of spot urine samples needed to estimate the iodine level in a population with 95 % confidence within a precision range of ± 10 % was about 125 (100 when using estimated 24 h iodine excretions), and within a precision range of ± 5 % was about 500 (400). A precision range of ± 20 % in an individual required twelve urine samples or more (seven when using estimated 24 h iodine excretions). In conclusion, estimating population iodine excretion requires 100–500 spot urine samples for each group or subgroup. Less than ten urine samples in an individual may be misleading.

scholarly journals Urinary iodine and other iodine deficiency indicators in a sample of school-age children in Egypt

2004 ◽  
Vol 10 (6) ◽  
pp. 863-870
Author(s):  
F. A. El Mougi ◽  
S. Abdel Ghaffar ◽  
N. A. F. Fayek ◽  
M. S. Mohammed
Keyword(s):  
Iodine Deficiency ◽  
Urinary Iodine ◽  
Iodine Concentration ◽  
School Age Children ◽  
Urinary Iodine Excretion ◽  
Urinary Iodine Concentration ◽  
Free Triiodothyronine ◽  
Severe Deficiency ◽  
Egyptian Children ◽  
Iodine Excretion

Sufficient data relating urinary iodine excretion in children to other iodine deficiency indicators are lacking in Egypt. We assayed urinary iodine concentration and serum levels of thyroid stimulating hormone [TSH], thyroglobulin, free triiodothyronine [T3] and free tetraiodothyronine in 99 school-aged Egyptian children. Goitre was found in 25 children. Median urinary iodine concentration was 70 micro g/L. We found mild iodine deficiency [50-99 micro g/L] in 60.6% of the children and moderate to severe deficiency [< 50 micro g/L] in 31.3%. The latter showed a high frequency of goitre and elevated mean serum free T3, TSH and thyroglobulin levels. Individual urinary iodine excretion rates vary, therefore these other indicators could help in screening for iodine deficiency at an individual level, especially in moderate to severe deficiency

Rezidivrisiko nach thyreostatischer Behandlung immunogener und nicht-immunogener Hyperthyreosen

1990 ◽  
Vol 29 (01) ◽  
pp. 1-6 ◽  
Author(s):  
E. Voth ◽  
N. Dickmann ◽  
H. Schicha ◽  
D. Emrich
Keyword(s):  
Relapse Rate ◽  
Urinary Iodine ◽  
Young Patients ◽  
Antithyroid Drugs ◽  
Urinary Iodine Excretion ◽  
Old Patients ◽  
Primary Disease ◽  
Iodine Excretion ◽  
Immunogenic Hyperthyroidism

Data of 196 patients treated for hyperthyroidism exclusively with antithyroid drugs were analyzed retrospectively concerning the relapse rate within a follow-up period of four years. Patients were subdivided for primary or recurrent disease, and for immunogenic or non-immunogenic hyperthyroidism, respectively. In immunogenic as well as in non-immunogeriic hyperthyroidism, the relapse rate was significantly lower for patients with primary disease (35% and 52%, respectively) compared to those with recurrent hyperthyroidism (82%, p <0.001 and 83%, p <0.001, respectively). In patients with primary disease, clinical, biochemical and scintigraphic parameters were tested with respect to their capability of predicting a relapse. For immunogenic hyperthyroidism the highest relapse rates were observed in young patients and in those with large goitres, whereas for non-immunogenic hyperthyroidism they were highest in old patients, in those with nodular goitres and in those without an increased urinary iodine excretion at the time of diagnosing hyperthyroidism.

Influence of Radioiodine Therapy on Urinary Iodine Excretion

1998 ◽  
Vol 37 (03) ◽  
pp. 107-112 ◽  
Author(s):  
I. Lauer ◽  
M. Bähre ◽  
E. Richter ◽  
B. Melier
Keyword(s):  
Time Course ◽  
Radioiodine Therapy ◽  
Urinary Iodine ◽  
Target Volume ◽  
Urinary Iodine Excretion ◽  
Urinary Creatinine ◽  
Iodine Excretion ◽  
Kinetics Of ◽  
Persistent Elevation ◽  
Benign Thyroid

Summary Aim: In 214 patients with benign thyroid diseases the time-course of urinary iodine excretion (UIE) was investigated in order to identify changes after radioiodine therapy (RITh). Method: UIE was measured photometrically (cerium-arsenite method) and related to urinary creatinine on the first and last day of the radioiodine test and then three days, seven days, four weeks, and six months after 1311 administration. Results: As compared with the level found immediately before radioiodine therapy, median UIE had almost doubled four weeks after therapy and was still significantly elevated six months after therapy. This increase correlated significantly with the target volume as measured by scintigraphy and sonography. Conclusions: The persistent elevation of UIE for months after RITh is a measure of treatment-induced damage to thyrocytes. Therefore, in view of the unfavourable kinetics of iodine that follow it, RITh should if possible be given via a single-dose regime.

scholarly journals Thirty years of a Ban on the Sale of Noniodized Salt: Impact on Iodine Nutrition in Children in Himachal Pradesh, India

2005 ◽  
Vol 26 (3) ◽  
pp. 255-258 ◽  
Author(s):  
Umesh Kapil ◽  
Thakur Dutt Sharma ◽  
Preeti Singh ◽  
Sada Nand Dwivedi ◽  
Supreet Kaur
Keyword(s):  
Positive Impact ◽  
Urinary Iodine ◽  
Iodine Content ◽  
Himachal Pradesh ◽  
The State ◽  
Urinary Iodine Excretion ◽  
Successful Implementation ◽  
Iodine Nutrition ◽  
Salt Iodization ◽  
Iodine Excretion

Background A survey conducted by the central iodine-deficiency disorders team in Himachal Pradesh, a state in the goiter-endemic belt of India, revealed that 10 of its 12 districts have an endemic prevalence of goiter. The survey was conducted to provide health program managers data to determine whether it would be necessary to initiate intervention measures. Objective To assess the status of urinary iodine excretion and household salt iodization levels after three decades of a complete ban on the sale of noniodized salt in this goiter-endemic state in India as measured by assessment of urinary iodine excretion levels and iodine content of salt at the household level. Methods The guidelines recommended by WHO/UNICEF/ICCIDD for a rapid assessment of salt iodization were adopted. In each of the 12 studied districts, all senior secondary schools were enlisted and one school was selected by using a random sampling procedure. Two hundred fifty children 11 to 18 years of age were included in the study. Urine samples were collected from a minimum of 170 children and analyzed using the wet digestion method. Salt samples were also collected from a minimum of 170 children and analyzed using the spot testing kit. Results All districts had a median urinary iodine excretion level > 200 μg/L and 82% of the families were consuming salt with an iodine content of 15 ppm or higher. Conclusions The results of the present study highlight the successful implementation of the salt iodization program in the state of Himachal Pradesh. This positive impact may be due to the comprehensive strategy adopted by the state government to improve the quality of salt, development of an effective monitoring information system and effective information, education, and communication activities.

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