Recombinant human thyrotropin-stimulated thyroglobulin level at the time of radioactive iodine ablation is an independent prognostic marker of differentiated thyroid carcinoma in the setting of prophylactic central neck dissection

2016 ◽  
Vol 85 (3) ◽  
pp. 459-465 ◽  
Author(s):  
Jae Hoon Moon ◽  
June Young Choi ◽  
Woo-Jin Jeong ◽  
Soon-Hyun Ahn ◽  
Won Woo Lee ◽  
...  
2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Kai-Pun Wong ◽  
Brian Hung-Hin Lang

Prophylactic central neck dissection (pCND) in differentiated thyroid carcinoma (DTC) is one of the most controversial surgical subjects in recent times. To date, there is little evidence to support the practice of pCND in patients with DTC undergoing total thyroidectomy. Although the recently revised American Thyroid Association (ATA) guideline has clarified many inconsistencies regarding pCND and has recommended pCND in “high-risk” patients, many issues and controversies surrounding the subject of pCND in DTC remain. The recent literature has revealed an insignificant trend toward lower recurrence rate in patients with DTC who undergo total thyroidectomy and pCND than those who undergo total thyroidectomy alone. However, this was subjected to biases, and there are concerns whether pCND should be performed by all surgeons who manage DTC because of increased surgical morbodity. Performing a unilateral pCND may be better than a bilateral pCND given its lower surgical morbidity. Further studies in this controversial subject are much needed.


1995 ◽  
Vol 2 (2) ◽  
pp. 107327489500200
Author(s):  
Christopher L. Alexander ◽  
Roberto E. Izquierdo ◽  
James Figge ◽  
John Horton

Thyroid carcinoma, which comprises the majority of endocrine malignancies, has a substantial annual morbidity and mortality based on age and other predisposing factors. Diagnosis of a growing thyroid nodule can be difficult, but ultrasonography, radionuclide scanning, and fine needle aspiration allow the majority of nodules to be properly characterized. Treatment of differentiated thyroid carcinoma remains controversial. Surgical resection continues to be the most important modality with long survival if the tumor is resected early. Newer imaging techniques have improved the diagnosis of locally recurrent or metastatic disease. Radioactive iodine ablation is indicated for patients with “high-risk” tumors or advanced age. Few patients respond to cytotoxic chemotherapy. In the past decade, advances in the screening and diagnosis of medullary thyroid carcinoma have led to earlier detection with improvement in survival.


2021 ◽  
Vol 264 ◽  
pp. 230-235
Author(s):  
Jonathan Dismukes ◽  
Jessica Fazendin ◽  
Ruth Obiarinze ◽  
Gianina C. Hernández Márquez ◽  
Kimberly M Ramonell ◽  
...  

2021 ◽  
Author(s):  
Khaled M. Alsubaie ◽  
Hemail M. Alsubaie ◽  
Faisal R. Alzahrani ◽  
Mohammad A. Alessa ◽  
Sherif K. Abdulmonem ◽  
...  

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