Scalp hair loss after transsphenoidal adenomectomy in patients with acromegaly

2013 ◽  
Vol 79 (3) ◽  
pp. 386-393 ◽  
Author(s):  
Shozo Yamada ◽  
Noriaki Fukuhara ◽  
Hiroshi Nishioka ◽  
Mitsuo Yamaguchi-Okada ◽  
Akira Takeshita ◽  
...  
Keyword(s):  
Hair Loss ◽  
Scalp Hair ◽  
Transsphenoidal Adenomectomy

scholarly journals Androgenetic alopecia: pathogenesis and potential for therapy

2002 ◽  
Vol 4 (22) ◽  
pp. 1-11 ◽  
Author(s):  
Justine A. Ellis ◽  
Rodney Sinclair ◽  
Stephen B. Harrap
Keyword(s):  
Androgen Receptor ◽  
Hair Loss ◽  
Genetic Predisposition ◽  
Scalp Hair ◽  
Androgenetic Alopecia ◽  
Growth Cycles ◽  
Men And Women ◽  
White Males ◽  
Determining Factors ◽  
The Many

Androgenetic alopecia occurs in men and women, and is characterised by the loss of hair from the scalp in a defined pattern. Determining factors appear to be genetic predisposition coupled with the presence of sufficient circulating androgens. The prevalence of this condition is high (up to 50% of white males are affected by 50 years of age) and, although there are no serious direct health consequences, the loss of scalp hair can be distressing. Knowledge of the pathogenesis of androgenetic alopecia has increased markedly in recent years. Pre-programmed follicles on the scalp undergo a transformation from long growth (anagen) and short rest (telogen) cycles, to long rest and short growth cycles. This process is coupled with progressive miniaturisation of the follicle. These changes are androgen dependent, and require the inheritance of several genes. To date, only one of these genes, which encodes the androgen receptor (AR), has been identified. Of the many treatments available for androgenetic alopecia, only two (finasteride and minoxidil) have been scientifically shown to be useful in the treatment of hair loss. However, these therapies are variable in their effectiveness. Discovery of the involvement of the AR gene, and the identification of other genes contributing to the condition, might lead to the development of new and more effective therapies that target the condition at a more fundamental level.

scholarly journals Association of type 2 diabetes with central-scalp hair loss in a large cohort study of African American women

2019 ◽  
Vol 5 (4) ◽  
pp. 261-266
Author(s):  
Patricia F. Coogan ◽  
Traci N. Bethea ◽  
Yvette C. Cozier ◽  
Kimberly A. Bertrand ◽  
Julie R. Palmer ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
African American ◽  
Cohort Study ◽  
African American Women ◽  
Hair Loss ◽  
Scalp Hair ◽  
Large Cohort ◽  
American Women ◽  
Large Cohort Study

Hair loss in women: medical and cosmetic approaches to increase scalp hair fullness

2011 ◽  
Vol 165 ◽  
pp. 12-18 ◽  
Author(s):  
R. Sinclair ◽  
M. Patel ◽  
T.L. Dawson ◽  
A. Yazdabadi ◽  
L. Yip ◽  
...  
Keyword(s):  
Hair Loss ◽  
Scalp Hair

scholarly journals Psoriatic Alopecia in a Patient with Systemic Lupus Erythematosus

2017 ◽  
Vol 9 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Wimolsiri Iamsumang ◽  
Tueboon Sriphojanart ◽  
Poonkiat Suchonwanit
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Female Patient ◽  
Hair Loss ◽  
Lupus Erythematosus ◽  
Clinical Presentation ◽  
Scalp Hair ◽  
Clinical Manifestations ◽  
Systemic Lupus ◽  
Scalp Psoriasis ◽  
Histopathologic Findings

Psoriasis is a chronic, recurrent, and relatively common inflammatory dermatologic condition, which demonstrates various clinical manifestations including hair loss. It was once believed that alopecia was not a presentation of scalp psoriasis, but it is now widely accepted that psoriatic alopecia exists. Although the majority of patients get hair regrowth, it can potentially lead to permanent hair loss. Herein, we report a case of 26-year-old female patient with systemic lupus erythematosus who presented with scalp hair loss and nonpruritic scaly plaques on the scalp. Her clinical presentation, dermoscopic, and histopathologic findings were consistent with psoriatic alopecia. Additionally, we also described a novel scalp dermoscopic pattern of “patchy dotted vessels” which we detected in the lesion of scalp psoriasis.

scholarly journals TENSILE STRENGTH OF SCALP HAIR IN WOMEN WITH HAIR LOSS

2020 ◽  
pp. 15-18
Author(s):  
Navein R K ◽  
Srivenkateswaran K ◽  
Sivasubramanian V ◽  
Sivakumar S ◽  
Sunjanaa Dhepa R L ◽  
...  
Keyword(s):  
Tensile Strength ◽  
Hair Loss ◽  
Case Control Study ◽  
Scalp Hair ◽  
Statistical Significance ◽  
Breaking Point ◽  
Chemical Treatments ◽  
Original Length ◽  
Study Results ◽  
Control Study

BACKGROUND :Hair loss may occur due to increase in breaking of hair due to a reduction in tensile strength of hair fiber.Resistance to breakage is a function of the cortex condition affected by chemical treatments. Normally hair can stretch upto 20% of its original length before breaking if its dry and upto 50% if its wet.AIM&OBJECTIVE : To evaluate the tensile strength of scalp hair in women with alopecia.METHODS :A case control study of about 50 cases with alopecia (assessed by Ludwig scale) and 50 controls with age and sex matched subjects of above 18 years of age were included.5 – 10 samples of 15 cms hair were collected from each subject and evaluated for tensile strength of both dry and wet samples with the help of zwick/roell machine.RESULTS :This study found that tensile strength breaking point Fmax (gF) dry was statistically significantly lower in cases(82.36±24.13) compared to controls (93.66±23.08), t(98)=-2.382, p=0.02. Similarly tensile strength breaking point Fmax (gF) wet was statistically significantly lower in cases(86.10±23.38) compared to controls (94.92±16.69), t(98)=-2.171, p=0.03. In the same way our study results showed that tensile strength breaking elongation dL at Fmax(%) dry and wet didn’t show any statistical significance between the two groups(p=0.50, p=0.53 respectively).CONCLUSION:This study shows that tensile strength of hair in women with alopecia had increased breakability in both dry and wet samples when compared with controls and also statistically significant whereas elasticity of hair was not statistically significant

scholarly journals A clinico-epidemiological study of scalp hair loss in children (0–18 years) in Kota Region, South-East Rajasthan

2019 ◽  
Vol 64 (4) ◽  
pp. 285
Author(s):  
Mukul Sharma ◽  
ManojKumar Sharma ◽  
Savera Gupta ◽  
Ramesh Kumar ◽  
AnilKumar Singhal ◽  
...  
Keyword(s):  
Epidemiological Study ◽  
Hair Loss ◽  
Scalp Hair

Circumscribed scalp hair loss following multiple hair-cutter ant invasion

2004 ◽  
Vol 10 (2) ◽  
Author(s):  
Shahin Aghaei ◽  
Manouchehr Sodaifi
Keyword(s):  
Hair Loss ◽  
Scalp Hair

Using qualitative methods to establish the clinically meaningful threshold for treatment success for the Severity of Alopecia Tool (SALT) score

2021 ◽  
Author(s):  
Kathleen W. Wyrwich ◽  
Helen Kitchen ◽  
Sarah Knight ◽  
Natalie V.J. Aldhouse ◽  
Jake Macey ◽  
...  
Keyword(s):  
Qualitative Methods ◽  
Hair Loss ◽  
Clinical Benefit ◽  
Scalp Hair ◽  
Treatment Success ◽  
Critical Role ◽  
Structured Interview ◽  
Individual Treatment ◽  
Qualitative Investigation ◽  
Meaningful Improvement

Abstract Purpose: Traditionally, appropriate anchors are used to investigate the amount of change on a clinician-reported outcome assessment that is meaningful to individual patients. However, novel qualitative methods can additionally inform the individual improvement threshold for demonstrating the clinical benefit of new treatments. This study aimed to establish a clinically meaningful threshold for treatment success for the clinician-reported Severity of Alopecia Tool (SALT) score for patients with alopecia areata (AA).Methods: A purposive sample of 10 dermatologists expert in the treatment of AA, and 30 adult and adolescent patients with AA and a history of ≥50% scalp hair loss were recruited. Semi-structured interview questions explored thresholds that represented treatment success to clinicians and patients with AA. Findings were analyzed using thematic methods to identify treatment success thresholds.Results: Expert clinicians considered a static threshold of 80% (n=5) or 75% (n=3) of the scalp hair as a treatment success. Patient responses ranged from 70 - 90% (median 80% of the scalp hair). Subsequently, queried patients confirmed that achieving SALT score ≤20 with treatment would be a success. Reflections on the methodology include: clinician perceptions can be informed by current clinical practice and knowledge of existing treatments and research and clinicians easily identified thresholds through qualitative discussions; patients were able to understand and identify thresholds for improvement less than complete absence of disease. Conclusions: This qualitative investigation of expert clinicians and patients with AA confirmed that achieving an amount of 80% or more scalp hair (SALT score ≤20) was an appropriate individual treatment success threshold indicating clinically meaningful improvement for patients with ≥50% scalp hair loss. A qualitative investigation of a quantifiable treatment success is possible through well-designed interview questions for the indication and patient population. Both clinician and patient input plays a critical role in understanding the clinical benefit meaningful to patients.

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