scholarly journals Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors

2017 ◽  
Vol 189 (1) ◽  
pp. 36-46 ◽  
Author(s):  
A. H. Bryant ◽  
G. E. Menzies ◽  
L. M. Scott ◽  
S. Spencer-Harty ◽  
L. B. Davies ◽  
...  
Keyword(s):  
Pattern Recognition ◽  
Nucleic Acid ◽  
Pattern Recognition Receptors ◽  
Human Gestation

Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis

2017 ◽  
Vol 74 (13) ◽  
pp. 2395-2411 ◽  
Author(s):  
Liangmei He ◽  
Yayun Chen ◽  
Yuanbing Wu ◽  
Ying Xu ◽  
Zixiang Zhang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Pattern Recognition ◽  
Nucleic Acid ◽  
Pattern Recognition Receptors

scholarly journals Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors

Platelets ◽  
2021 ◽  
pp. 1-13
Author(s):  
Samantha J. Montague ◽  
Pushpa Patel ◽  
Eleyna M. Martin ◽  
Alexandre Slater ◽  
Lourdes Garcia Quintanilla ◽  
...  
Keyword(s):  
Pattern Recognition ◽  
Platelet Activation ◽  
Pattern Recognition Receptors ◽  
Platelet Glycoprotein ◽  
Charged Ligands

scholarly journals Recognize Yourself—Innate Sensing of Non-LTR Retrotransposons

Viruses ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 94
Author(s):  
Justine Lagisquet ◽  
Kilian Zuber ◽  
Thomas Gramberg
Keyword(s):  
Pattern Recognition ◽  
Nucleic Acid ◽  
Autoimmune Diseases ◽  
Ltr Retrotransposons ◽  
Autoinflammatory Disorders ◽  
Protective Measures ◽  
Active Elements ◽  
Enhanced Expression ◽  
Long Interspersed Element

Although mobile genetic elements, or transposons, have played an important role in genome evolution, excess activity of mobile elements can have detrimental consequences. Already, the enhanced expression of transposons-derived nucleic acids can trigger autoimmune reactions that may result in severe autoinflammatory disorders. Thus, cells contain several layers of protective measures to restrict transposons and to sense the enhanced activity of these “intragenomic pathogens”. This review focuses on our current understanding of immunogenic patterns derived from the most active elements in humans, the retrotransposons long interspersed element (LINE)-1 and Alu. We describe the role of known pattern recognition receptors in nucleic acid sensing of LINE-1 and Alu and the possible consequences for autoimmune diseases.

scholarly journals Pattern recognition receptors: A contemporary view on liver diseases

Hepatology ◽  
2006 ◽  
Vol 44 (2) ◽  
pp. 287-298 ◽  
Author(s):  
Gyongyi Szabo ◽  
Angela Dolganiuc ◽  
Pranoti Mandrekar
Keyword(s):  
Pattern Recognition ◽  
Liver Diseases ◽  
Pattern Recognition Receptors ◽  
Contemporary View
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