Scurvy: A Forgotten Cause of Purpuric Rash

2021 ◽  
Author(s):  
R. Ward ◽  
N. Fox ◽  
J. Natkunarajah
Keyword(s):  
Purpuric Rash

A Woman With a Purpuric Rash and Weakness

2016 ◽  
Vol 50 (5) ◽  
pp. e239-e240
Author(s):  
Annika M.A. Berends ◽  
Tycho J. Olgers ◽  
Jan C. ter Maaten
Keyword(s):  
Purpuric Rash

Nonthrombocytopenic Purpura Associated Sequentially with Nifedipine and Diltiazem

1992 ◽  
Vol 26 (9) ◽  
pp. 1089-1090 ◽  
Author(s):  
Margaret Kuo ◽  
Nancy Winiarski ◽  
Serafino Garella
Keyword(s):  
Adverse Effect ◽  
Channel Blocker ◽  
Case Reports ◽  
Data Extraction ◽  
Data Sources ◽  
Cutaneous Vasculitis ◽  
Laboratory Studies ◽  
Pertinent Literature ◽  
Data Synthesis ◽  
Purpuric Rash

OBJECTIVE: To report the case of a patient who developed nonthrombocytopenic purpura sequentially following the administration of nifedipine and diltiazem. DATA SOURCES: Case reports, MEDLINE review of pertinent literature, and review of relevant studies. DATA EXTRACTION: Data were extracted from direct patient observation and review of laboratory studies and published reports. DATA SYNTHESIS: Nonthrombocytopenic purpura secondary to cutaneous vasculitis is a known, although rare, adverse effect of nifedipine. It has not been reported in association with diltiazem. We report the case of a 75-year-old woman in whom a purpuric rash demonstrated by biopsy to be attributable to cutaneous vasculitis developed in the course of nifedipine therapy. The rash disappeared after discontinuation of the drug; however, it recurred when diltiazem therapy was initiated. CONCLUSIONS: Nonthrombocytopenic purpura may be associated with diltiazem as well as with nifedipine. When this adverse effect occurs following administration of a calcium-channel blocker, caution is advised in using other agents of the same class.

IDIOPATHIC, RECURRENT CHOLESTASIS

PEDIATRICS ◽  
1970 ◽  
Vol 45 (5) ◽  
pp. 812-820
Author(s):  
Frederick B. Ruymann ◽  
Akio Takeuchi ◽  
H. Worth Boyce
Keyword(s):  
Age Of Onset ◽  
Serum Alkaline Phosphatase ◽  
Bile Canaliculi ◽  
Electron Microscopic ◽  
Portal Triad ◽  
Caucasian Girl ◽  
Younger Age ◽  
Oral Steroids ◽  
Liver Biopsies ◽  
Purpuric Rash

Idiopathic, recurrent cholestasis is characterized by episodes of obstructive jaundice often preceded by pruritus, steatorrhea, and purpuric rash. Between episodes of jaundice the liver histology is normal. We report a case of idiopathic, recurrent cholestasis occurring in a 14-year-old Caucasian girl who has experienced seven episodes of jaundice since 8 years of age. Serum alkaline phosphatase elevation preceded clinical jaundice. During remission the bromsulphalein excretion was normal. Response to oral steroids occurred when used after 4 weeks of jaundice. Cholestyramine resin and cyproheptadine relieved pruritus and in combination may have prevented progressive jaundice when administered early. Light microscopy during exacerbation showed centrilobular cholestasis with a slight mononuclear infiltration of the portal triad. The electron microscopic examinations demonstrate dilated bile canaliculi with altered microvilli. Serial liver biopsies over 6 years show no fibrosis or cytoplasmic alterations of hepatocytes. Of the 24 reported cases of idiopathic, recurrent cholestasis, two-thirds have been in males and had onset of jaundice under 20 years of age. This younger age of onset merits a greater awareness by the practicing pediatrician. After the diagnosis is established by clinical, biochemical, and morphologic studies, a benign course can be anticipated.

A 12-Year-Old Boy with a Purpuric Rash

2009 ◽  
Vol 38 (8) ◽  
pp. 414-418 ◽  
Author(s):  
Rachael Ekstrand ◽  
Jennifer Reed
Keyword(s):  
Purpuric Rash

scholarly journals Purpuric rash due to epsilon-aminocaproic acid.

BMJ ◽  
1980 ◽  
Vol 281 (6234) ◽  
pp. 197-198 ◽  
Author(s):  
A Chakrabarti ◽  
K A Collett
Keyword(s):  
Aminocaproic Acid ◽  
Epsilon Aminocaproic Acid ◽  
Purpuric Rash

scholarly journals Normocomplementaemic Urticarial Vasculitis in a 19-Month-Old Girl

2016 ◽  
Vol 2016 ◽  
pp. 1-2
Author(s):  
Peter Williams
Keyword(s):  
Renal Function ◽  
Normal Level ◽  
Vital Signs ◽  
Activated Partial Thromboplastin Time ◽  
Similar Distribution ◽  
Urticarial Vasculitis ◽  
Urticarial Rash ◽  
Erythrocyte Sedimentation ◽  
International Normalised Ratio ◽  
Purpuric Rash

Urticaria is common in children. Urticarial vasculitis (UV) is a potentially more serious, rare variant. The youngest reported case was 12 months of age. A systemically well, 19-month-old girl presented with her mother who was concerned about the development of a rash. On presentation, the child had normal vital signs, was alert, and was well and playing with toys. There was a widespread urticarial rash (raised, pruritic, and erythematous) that was most apparent on the trunk with minimal rash on the legs. Overlying this urticarial rash in a similar distribution was a blotchy, palpable purpuric rash and associated hyperpigmentation. Investigations revealed a normal level of haemoglobin, white cells, platelets, and electrolytes. Renal function, international normalised ratio, and activated partial thromboplastin time were all normal. There was no blood or protein in the urine. The erythrocyte sedimentation rate was mildly elevated at 19 mm/hour. Complement results (including C1q) obtained later were normal. This case is striking not only because of the rarity of UV in children but also due to the unique diagnostic and prognostic challenges that it raises.

Residents’ corner. sQuiz your knowledge: Acute painful purpuric rash

2017 ◽  
Vol 27 (1) ◽  
pp. 106-107 ◽  
Author(s):  
Lidia Ossorio-garcía ◽  
Cintia Arjona-aguilera ◽  
David Jiménez-gallo
Keyword(s):  
Purpuric Rash

A Common Purpuric Rash With Uncommon Association in a Woman With Pedal Edema

JAMA Oncology ◽  
2019 ◽  
Vol 5 (7) ◽  
pp. 1057
Author(s):  
Tauseef Akhtar ◽  
Ankit Mangla
Keyword(s):  
Pedal Edema ◽  
Purpuric Rash

scholarly journals Petechial purpuric rash after non-invasive blood pressure measurement: Rumpel-Leede sign

2019 ◽  
Vol 12 (10) ◽  
pp. e231541
Author(s):  
Bram Doron van Rhijn ◽  
Georgios Jannis Vlachojannis ◽  
Deepak Mukesh Wieshwaykumar Balak
Keyword(s):  
Blood Pressure ◽  
Pressure Measurement ◽  
Blood Pressure Measurement ◽  
Invasive Blood Pressure ◽  
Non Invasive ◽  
Invasive Blood Pressure Measurement ◽  
Purpuric Rash

scholarly journals Cerebral Microhemorrhage and Purpuric Rash in COVID-19: The Case for a Secondary Microangiopathy

2020 ◽  
Vol 29 (10) ◽  
pp. 105111 ◽  
Author(s):  
Aaron Shoskes ◽  
Ibrahim Migdady ◽  
Anthony Fernandez ◽  
Paul Ruggieri ◽  
Alexander Rae-Grant
Keyword(s):  
Cerebral Microhemorrhage ◽  
Purpuric Rash
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