An unusual case of longstanding mammary Paget's disease presenting with reticulated skin changes

2021 ◽  
Author(s):  
S. Dhariwal ◽  
E. Rytina ◽  
J. Sterling
Keyword(s):  
Unusual Case ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Skin Changes ◽  
Mammary Paget’S Disease

scholarly journals An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Eleonora Gaspari ◽  
Aurora Ricci ◽  
Valeria Liberto ◽  
Angela Lia Scarano ◽  
Maria Fornari ◽  
...  
Keyword(s):  
Unusual Case ◽  
Ductal Carcinoma ◽  
Paget’S Disease ◽  
Skin Lesions ◽  
Paget's Disease ◽  
Mri Findings ◽  
Rare Presentation ◽  
Nipple Areola Complex ◽  
Areola Complex ◽  
Mammary Paget’S Disease

Mammary Paget’s disease is a rare presentation of breast cancer. At clinical examination, it is characterized by skin lesions of the nipple-areola complex, almost always a sign of malignancy. In fact, it is often associated with an underlying mammary ductal carcinoma in situ (DCIS) or invasive carcinoma. An underlying carcinoma is also common in women with negative mammography and ultrasound (US); in these cases, magnetic resonance imaging (MRI) is a diagnostic tool useful in the detection of occult cancer. We described an unusual case of mammary Paget’s disease with underlying DCIS, in a patient without nipple-areola complex alterations and/or palpable lump. On suspicion of Paget’s disease, the patient underwent MRI examination that proved useful for an accurate diagnosis. Biopsy confirmed dynamic MRI findings.

Not All Cases of Mammary Paget’s Disease are Cytokeratin-7 Positive: A Challenging Diagnosis!

2021 ◽  
pp. 106689692110029
Author(s):  
Kerschen Anja ◽  
Dano Hélène ◽  
Van Eeckhout Pascal ◽  
Marot Liliane ◽  
Van Bockstal Mieke
Keyword(s):  
Present Report ◽  
Paget’S Disease ◽  
Growth Factor Receptor ◽  
Punch Biopsy ◽  
Paget's Disease ◽  
Cytokeratin 7 ◽  
In Situ Carcinoma ◽  
Epidermal Growth ◽  
Mammary Paget’S Disease

Mammary Paget’s disease accounts for 1% to 3% of all breast tumors and manifests as a chronic eczematous lesion of the areolar skin. It can occur without any underlying neoplasia or can be present in association with an underlying invasive and/or in situ carcinoma of the breast. The present report describes a challenging nipple punch biopsy showing an infiltration of the lower third to two-thirds of the epidermis by large, ovoid, neoplastic cells. The morphology was consistent with mammary Paget's disease, although immunohistochemistry for cytokeratin-7 (CK7) was repeatedly negative. This resulted in an initial misdiagnosis and, subsequently, a delay in the patient's follow-up. Additional immunohistochemistry for GATA binding protein 3 (GATA3) and human epidermal growth factor receptor 2 (HER2), as well as a second opinion of a breast pathologist, resulted in the diagnosis of mammary Paget's disease. The aim of this article is to raise awareness among pathologists and prevent them from misdiagnosing CK7-negative Paget disease of the breast.

scholarly journals A case of the maxillary carcinoma with the extra-mammary Paget's disease.

1987 ◽  
Vol 33 (3) ◽  
pp. 566-569
Author(s):  
Junichiro NUKATA ◽  
Tetsuro SUMI ◽  
Masayoshi SAKUDA ◽  
Kazuyoshi TOMITA
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Mammary Paget’S Disease

scholarly journals Advanced lesions of synchronous bilateral mammary Paget’s disease: a case report

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Lina Choridah ◽  
Wida Kartika Sari ◽  
Ery Kus Dwianingsih ◽  
Irianiwati Widodo ◽  
Suwardjo ◽  
...  
Keyword(s):  
Case Report ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Mammary Paget’S Disease

Pigmented mammary Paget's disease

2007 ◽  
Vol 21 (6) ◽  
pp. 844-846 ◽  
Author(s):  
J del Boz ◽  
A Sanz ◽  
T Martín ◽  
S Martínez ◽  
V Sánchez ◽  
...  
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Mammary Paget’S Disease

Cytokeratin 7-negative mammary Paget's disease: A diagnostic pitfall

2016 ◽  
Vol 212 (4) ◽  
pp. 279-281 ◽  
Author(s):  
Ugur Ozerdem ◽  
Jennifer M. McNiff ◽  
Fattaneh A. Tavassoli
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Cytokeratin 7 ◽  
Diagnostic Pitfall ◽  
Mammary Paget’S Disease

A case of mammary Paget's disease showing a dark brown patch surrounded by pigmented lesion

Skin Cancer ◽  
2009 ◽  
Vol 24 (2) ◽  
pp. 267-271
Author(s):  
Noriko SUZUKI ◽  
Hazuki KAGEYAMA ◽  
Fumihiko TANIOKA ◽  
Michiko Imai
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Brown Patch ◽  
Pigmented Lesion ◽  
Mammary Paget’S Disease
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