Therapeutic efficacy and safety of oral tranexamic acid and that of tranexamic acid local infiltration with microinjections in patients with melasma: a comparative study

2017 ◽  
Vol 42 (7) ◽  
pp. 728-734 ◽  
Author(s):  
R. Sharma ◽  
V. K. Mahajan ◽  
K. S. Mehta ◽  
P. S. Chauhan ◽  
R. Rawat ◽  
...  
Keyword(s):  
Tranexamic Acid ◽  
Comparative Study ◽  
Therapeutic Efficacy ◽  
Efficacy And Safety ◽  
Local Infiltration

Therapeutic efficacy and safety of oral tranexamic acid 250 mg once a day versus 500 mg twice a day: a comparative study

2020 ◽  
Author(s):  
Bhumika Chowdhary ◽  
Vikram K. Mahajan ◽  
Karaninder S. Mehta ◽  
Pushpinder S. Chauhan ◽  
Vikas Sharma ◽  
...  
Keyword(s):  
Tranexamic Acid ◽  
Comparative Study ◽  
Therapeutic Efficacy ◽  
Efficacy And Safety

scholarly journals Evaluation of Therapeutic Efficacy and Safety of Tranexamic Acid Local Infiltration in Combination with Topical 4% Hydroquinone Cream Compared to Topical 4% Hydroquinone Cream Alone in Patients with Melasma: A Split-Face Study

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Zohreh Tehranchinia ◽  
Bita Saghi ◽  
Hoda Rahimi
Keyword(s):  
Tranexamic Acid ◽  
Efficacy And Safety ◽  
Local Infiltration ◽  
Patient’S Satisfaction ◽  
Treatment Groups ◽  
Exposed Skin ◽  
Therapeutic Outcomes ◽  
Satisfaction With Treatment ◽  
The Difference ◽  
Split Face

Introduction. Melasma is an acquired pigmentary disorder characterized by hyperpigmented macules and/or patches affecting sun-exposed skin. Tranexamic acid (TA) can reduce melanin content of epidermis. Thus, we conducted this study to evaluate the efficacy and safety of tranexamic acid local infiltration in combination with topical 4% hydroquinone cream compared to topical 4% hydroquinone cream alone in patients with melasma.Material and Methods. This study was a prospective assessor- and analyst-blind, randomized split-face clinical trial which was performed on patients with bilateral malar epidermal melasma. A total of 55 patients were enrolled, and each side of their face was randomly allocated to either TA+HQ or HQ alone treatment. The MASI score was applied as an objective measurement to compare two treatment groups. The patient's satisfaction of melasma treatment was evaluated using a four-scale grading, as well.Results. The mean of MASI score in week 16 decreased in both groups significantly (p < 0.01). The therapeutic outcomes were significantly better in TA+HQ group than HQ group (p=0.001). Patients satisfaction with treatment was significantly higher in the TA + HQ group. The difference between the two groups regarding side effect occurrence was not statistically significant.Conclusion. Addition of tranexamic acid injections to conventional hydroquinone therapy can increase the efficacy of topical treatment.This trial is registered withIRCT2015110324865N1.

Efficacy and safety of a novel water‐soluble herbal patch for acne vulgaris treatment: a randomized, assessor‐blinds controlled, intra‐individual split‐face comparative study

2021 ◽  
Author(s):  
Kulwipapat Jaturapisanukul ◽  
Montree Udompataikul ◽  
Silada kanolrungsee ◽  
Salinee Rojhirunsakool ◽  
Nanticha kamanamool ◽  
...  
Keyword(s):  
Comparative Study ◽  
Acne Vulgaris ◽  
Water Soluble ◽  
Efficacy And Safety ◽  
Split Face

Therapeutic Efficacy and Safety of Korean Red Ginseng During Cyclosporine Treatment.

2014 ◽  
Vol 98 ◽  
pp. 283
Author(s):  
S. Lim ◽  
K. Doh ◽  
L. Jin ◽  
S. Piao ◽  
S. Heo ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Efficacy And Safety ◽  
Red Ginseng ◽  
Korean Red Ginseng
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