scholarly journals Allergen skin test reactivity and asthma are inversely associated with ratios of IgG4/IgE and total IgE/allergen‐specific IgE in Ugandan communities

2021 ◽  
Author(s):  
Gyaviira Nkurunungi ◽  
Jacent Nassuuna ◽  
Harriet Mpairwe ◽  
Joyce Kabagenyi ◽  
Margaret Nampijja ◽  
...  
Keyword(s):  
Skin Test ◽  
Specific Ige ◽  
Skin Test Reactivity ◽  
Total Ige

scholarly journals Racial differences in the association of CD14 polymorphisms with serum total IgE levels and allergen skin test reactivity

2013 ◽  
pp. 81 ◽  
Author(s):  
Sophie Wang ◽  
John Sundy ◽  
Catherine M. Foss ◽  
Huiman X. Barnhart ◽  
Scott M. Palmer ◽  
...  
Keyword(s):  
Racial Differences ◽  
Skin Test ◽  
Skin Test Reactivity ◽  
Total Ige ◽  
Serum Total Ige

MEASUREMENT OF TOTAL AND SPECIFIC IMUNOGLOBULIN E IN ADULT PATIENT WITH BRONCHIAL ASTHMA

2008 ◽  
Vol 37 (2) ◽  
pp. 132-136
Author(s):  
Fejzo Dzafic ◽  
Amer Custovic ◽  
Sead Jamakosmanovic ◽  
Damir Sabitovic ◽  
Indira Sejranic ◽  
...  
Keyword(s):  
Adult Patient ◽  
Skin Test ◽  
Bronchial Asthma ◽  
House Dust ◽  
Grass Pollen ◽  
Airway Disease ◽  
Specific Ige ◽  
Total Ige ◽  
Inflammatory Airway Disease ◽  
Allergic Bronchial Asthma

Introduction: Asthma is a chronic inflammatory airway disease, with more present allergic component who cause disease. Pacient and Metods: In this study was included 35 patients who had been bronchial asthma whom was made total IgE determined by nefelometric metod and skin test by Prick metod. Subjects which had increased values of IgE, had been tested for fecal parasites . Subjects wich was positiv for scin allergens was tested for specific IgE on Hytec 288 instrument with ELISA metod. Results: Folowing resaults was obtained: 57.14% (20) of subjects had increased values of total IgE, while 42.86% (15) had normal total IgE. All patients with increased values of total IgE were tested negative for fecal parazites. Percent conform Prick tests and specific IgE was for house dust 54.55%, ragweed 53.85%, grass pollen 45.45%, Dermato-phagoides Pteronyssinus 43.75%, Pollen trees 25.00%. Conclusion and Discussion: Allergic bronchial asthma capture big percent in patients with bronchial asthma. The most frequent allergen was house dust.

scholarly journals Effects of geohelminth infection and age on the associations between allergen‐specific IgE, skin test reactivity and wheeze: a case‐control study

2012 ◽  
Vol 43 (1) ◽  
pp. 60-72 ◽  
Author(s):  
A.‐L. Moncayo ◽  
M. Vaca ◽  
G. Oviedo ◽  
L. J. Workman ◽  
M. E. Chico ◽  
...  
Keyword(s):  
Skin Test ◽  
Case Control Study ◽  
Specific Ige ◽  
Case Control ◽  
Skin Test Reactivity ◽  
Control Study

scholarly journals Studies of the Relationship between Allergen-Specific IgE Antibodies and Skin Test Reactivity in Patients with Asthma in Kuwait

2000 ◽  
Vol 9 (4) ◽  
pp. 260-267 ◽  
Author(s):  
M.E. Khadadah ◽  
B.O. Onadeko ◽  
C.I. Ezeamuzie ◽  
R. Maroof ◽  
H.S. Mustafa ◽  
...  
Keyword(s):  
Skin Test ◽  
Specific Ige ◽  
Skin Test Reactivity ◽  
Ige Antibodies ◽  
Specific Ige Antibodies ◽  
The Relationship

scholarly journals Principal Components Analysis of Atopy-Related Traits in a Random Sample of Children

ISRN Allergy ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Simon Francis Thomsen ◽  
Vibeke Backer
Keyword(s):  
Atopic Dermatitis ◽  
Principal Components Analysis ◽  
Random Sample ◽  
Skin Test ◽  
Principal Components ◽  
Skin Test Reactivity ◽  
Total Ige ◽  
Components Analysis ◽  
Serum Total Ige ◽  
The Relationship

Aim. To study the relationship between atopy-related traits in a random sample of children. Methods. A total of 1007 randomly selected children, 7–17 years of age, from Copenhagen, Denmark were studied. The children were interviewed about symptoms of atopic diseases, and skin test reactivity, serum total IgE, lung function, and airway responsiveness were measured. Principal components analysis was performed in order to examine the relationship between the different traits. Results. Most of the studied traits were significantly correlated. A three-component solution explained about 55% of the variation in the observed traits. The first component loaded most strongly on hay fever, serum total IgE, skin test reactivity and sensitisation to grass, cat and house dust mite allergen; the second factor was most associated with asthma, airway obstruction, and airway hyperresponsiveness, whereas the third factor corresponded most strongly to atopic dermatitis. There was some indication of cross-relations between the three components with respect to serum total IgE. Conclusion. Asthma, hay fever, and atopic dermatitis are characterised by different sets of biomarkers suggestive of a high degree of heterogeneity within the atopic syndrome.

Real-World Data Evaluation Of Total IgE, Specific IgE And Omalizumab Therapy In A Cohort Of Allergic Asthma Patients Treated In A Community-Based Practice

2020 ◽  
Author(s):  
Fortune O Alabi
Keyword(s):  
Allergic Asthma ◽  
Specific Ige ◽  
Forced Expiratory Volume ◽  
Act Scores ◽  
Asthma Control Test ◽  
Real World Data ◽  
Total Ige ◽  
Prick Test ◽  
Negative Results ◽  
Asthma Patients

Objective: In this study, we: (1) evaluated the correlation between total IgE and the presence of specific IgE; (2) compared the characteristics of patients with positive specific IgE to those with negative specific IgE; and, (3) analyzed the allergic testing results of patients on omalizumab and reported the effect of omalizumab on forced expiratory volume (FEV1) and asthma control test (ACT) results. Methods: Data from patients diagnosed with allergic asthma and seen at Florida Lung, Asthma & Sleep Specialists (FLASS) between January 2016 and June 2019 were analyzed. Parameters evaluated were total IgE, and levels of specific IgE to antigens in the ImmunoCAP test and skin prick test (SPT). Additional parameters for patients on omalizumab therapy for at least 6 months were FEV1, % predicted FEV1 and ACT results. Results: A total of 475 patients (114 males, 361 females) met the inclusion criteria. The mean age was 53 years (range: 17 to 89 years). Of these, 36 patients were not included in the analysis due to incomplete data. Mean total IgE was higher in patients with positive ImmunoCAP results compared to those with negative results (396 KU/L vs. 81.3 KU/L). There was a significant positive correlation between total IgE and levels of positive specific IgE in the ImmunoCAP test (p<0.0001, r=0.36, n=213 patients). The correlation between total IgE and levels of positive allergens in SPT was not significant (p=0.15, n=44 patients) Two positive reactions to allergens were seen in 22% of ImmunoCAP tests and 13% of SPT tests. There was no statistically significant improvement in FEV1 (p=0.097, CI -0.17 to 0.02) and % predicted FEV1 (p=0.109, CI -6.63 to 0.70) in patients who used omalizumab for at least 6 months. There was a statistically significant improvement in ACT scores (p=0.031, CI -4.21 to -0.21) in patients who used omalizumab for at least 6 months. Conclusion: Allergic asthma could be seen in patients who had an absence of specific IgE in ImmunoCAP and a negative reaction to SPT. The benefit of omalizumab therapy is not limited to allergic asthma patients with positive specific IgE.

Comparative Incidence of Skin Test Reactivity to Johnson, Timothy, and Bermuda Grasses in San Francisco

2021 ◽  
Vol 147 (2) ◽  
pp. AB83
Author(s):  
Christina B. Phan ◽  
Bryce Hoffman ◽  
Andrew Louie ◽  
Julia Wei ◽  
Peg Strub
Keyword(s):  
San Francisco ◽  
Skin Test ◽  
Skin Test Reactivity
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