Effect of topical corticosteroids on allergic airway inflammation and disease severity in obstructive sleep apnea

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Francois Lavigne ◽  
Basil J. Petrof ◽  
Jill R. Johnson ◽  
Philippe Lavigne ◽  
Najat Binothman ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Airway Inflammation ◽  
Disease Severity ◽  
Allergic Airway Inflammation ◽  
Topical Corticosteroids ◽  
Obstructive Sleep

scholarly journals Airway inflammation in patients affected by obstructive sleep apnea

2016 ◽  
Vol 65 (2) ◽  
Author(s):  
R. Sabato ◽  
P. Guido ◽  
F.G. Salerno ◽  
O. Resta ◽  
A. Spanevello ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Airway Inflammation ◽  
Systemic Inflammation ◽  
Inflammatory Mediators ◽  
Upper Airway ◽  
Airway Hyperreactivity ◽  
Variable Degree ◽  
Airway Occlusion ◽  
Obstructive Sleep

Obstructive sleep apnea (OSA) is characterised by repetitive episodes of upper airway occlusion during sleep. OSA has been shown to be associated with a variable degree of nasal inflammation, uvula mucosal congestion and airway hyperreactivity. The upper airway inflammation, whose clinical importance is uncertain, is characterised by leukocytes infiltration and interstitial oedema. In addition, recent data has shown the presence of neutrophilic inflammation in the lower airways. The current opinion is that airway inflammation is caused by the local, repeated mechanical trauma related to the intermittent airway occlusion typical of the disease. Another potential mechanism involves the intermittent nocturnal hypoxemia that through the phenomenon of the ischemia- reperfusion injury may induce the production of oxygen free radicals and therefore cause local and systemic inflammation. Finally, a state of low-grade systemic inflammation may be related to obesity per se with the pro-inflammatory mediators synthesised in the visceral adipose cells. Several authors stress the role of circulating and local inflammatory mediators, such as proinflammatory cytokines, exhaled nitric oxide, pentane and 8-isoprostane as the determinants of inflammation in OSA.

OBSTRUCTIVE SLEEP APNEA IN UNTREATED HYPERTENSIVE PATIENTS: ASSOCIATIONS OF DISEASE SEVERITY WITH DIVERSE ATHEROSCLEROTIC MARKERS

2011 ◽  
Vol 29 ◽  
pp. e227
Author(s):  
A. Kasiakogias ◽  
C. Tsioufis ◽  
C. Thomopoulos ◽  
E. andrikou ◽  
A. Kordalis ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Disease Severity ◽  
Hypertensive Patients ◽  
Obstructive Sleep

scholarly journals Role of lung volume and airway inflammation in obstructive sleep apnea

2017 ◽  
Vol 55 (6) ◽  
pp. 326-333 ◽  
Author(s):  
Andras Bikov ◽  
Gyorgy Losonczy ◽  
Laszlo Kunos
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Airway Inflammation ◽  
Lung Volume ◽  
Obstructive Sleep

scholarly journals Connection between bone remodeling and inflammatory markers in obstructive sleep apnea in relation to disease severity: a preliminary study

2017 ◽  
Author(s):  
Barbara Bromińska ◽  
Ewa Cyrańska-Chyrek ◽  
Barbara Kuźnar-Kamińska ◽  
Magdalena Kostrzewska ◽  
Hanna Winiarska ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Bone Remodeling ◽  
Disease Severity ◽  
Inflammatory Markers ◽  
Obstructive Sleep ◽  
Preliminary Study

P465 Ethnic differences in symptoms of obstructive sleep apnea and relation to disease severity

2006 ◽  
Vol 7 ◽  
pp. S118 ◽  
Author(s):  
Shyam Subramanian ◽  
Sreenivasa Chanamolu ◽  
Venkata Rebbapragada ◽  
Kalpalatha Guntupalli ◽  
Bela Patel ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Disease Severity ◽  
Ethnic Differences ◽  
Obstructive Sleep

scholarly journals P-443 Circadian variation of heart rate variabilty is associated with disease severity in obstructive sleep apnea

EP Europace ◽  
2003 ◽  
Vol 4 (Supplement_2) ◽  
pp. B170-B170
Author(s):  
I. Can ◽  
K. Aytemir ◽  
A. Deniz ◽  
L. Tokgozoglu ◽  
G. Kabakci ◽  
...  
Keyword(s):  
Heart Rate ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Disease Severity ◽  
Circadian Variation ◽  
Obstructive Sleep

scholarly journals Airway inflammation in patients affected by obstructive sleep apnea syndrome

2004 ◽  
Vol 98 (1) ◽  
pp. 25-28 ◽  
Author(s):  
F.G Salerno ◽  
E Carpagnano ◽  
P Guido ◽  
M.R Bonsignore ◽  
A Roberti ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Airway Inflammation ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Obstructive Sleep ◽  
Apnea Syndrome
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