Discovery of a novel and orally active FXR agonist for the protection of APAP‐induced hepatotoxicity

Faculty Opinions recommendation of Discovery of (R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol- 6(2H)-one, a selective, orally active agonist of the 5-HT(2C) receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1071947.524897 ◽

2007 ◽

Author(s):

Thomas W von Geldern

Keyword(s):

Orally Active

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Faculty Opinions recommendation of Manganese(III) complexes of bis(hydroxyphenyl)dipyrromethenes are potent orally active peroxynitrite scavengers.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13293993.14653112 ◽

2011 ◽

Author(s):

Larry K Keefer

Keyword(s):

Orally Active ◽

Peroxynitrite Scavengers

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Faculty Opinions recommendation of Discovery of a novel class of orally active antifungal beta-1,3-D-glucan synthase inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14264196.15777357 ◽

2012 ◽

Author(s):

Mahmoud Ghannoum ◽

Pranab Mukherjee

Keyword(s):

Glucan Synthase ◽

Orally Active

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Faculty Opinions recommendation of Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726064698.793513052 ◽

2016 ◽

Author(s):

John Lowe

Keyword(s):

Orally Active

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Faculty Opinions recommendation of Phenotypic Optimization of Urea-Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.731932185.793538369 ◽

2017 ◽

Author(s):

John Lowe

Keyword(s):

Hearing Loss ◽

Protective Agents ◽

Orally Active

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Faculty Opinions recommendation of Discovery of orally active hydroxyethylamine based sppl2a inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.735822888.793560675 ◽

2019 ◽

Author(s):

John Lowe

Keyword(s):

Orally Active

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Faculty Opinions recommendation of Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8282963.8711064 ◽

2011 ◽

Author(s):

David Welsh

Keyword(s):

Receptor Antagonist ◽

Endothelin Receptor Antagonist ◽

Endothelin Receptor ◽

Tissue Targeting ◽

Orally Active

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Faculty Opinions recommendation of Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.9144957.9727058 ◽

2011 ◽

Author(s):

Manoj Desai ◽

Gregory Notte

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Virus Infection ◽

Hepatitis C Virus Infection ◽

Orally Active

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Antithrombotic Effects of Orally Active Synthetic Antagonist of Activated Factor X in Nonhuman Primates

Circulation ◽

10.1161/01.cir.92.3.485 ◽

1995 ◽

Vol 92 (3) ◽

pp. 485-491 ◽

Cited By ~ 39

Author(s):

Toru Yokoyama ◽

Andrew B. Kelly ◽

Ulla M. Marzec ◽

Stephen R. Hanson ◽

Satoshi Kunitada ◽

...

Keyword(s):

Nonhuman Primates ◽

Factor X ◽

Antithrombotic Effects ◽

Orally Active

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Extended Inhibition of Platelet Aggregation With the Orally Active Platelet Inhibitor SC-54684A

Circulation ◽

10.1161/01.cir.91.2.411 ◽

1995 ◽

Vol 91 (2) ◽

pp. 411-416 ◽

Cited By ~ 19

Author(s):

James A. Szalony ◽

Neal F. Haas ◽

Anita K. Salyers ◽

Beatrice B. Taite ◽

Nancy S. Nicholson ◽

...

Keyword(s):

Platelet Aggregation ◽

Platelet Inhibitor ◽

Inhibition Of Platelet Aggregation ◽

Orally Active

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