Antiproliferative activity of ester derivatives of monensin A at the C‐1 and C‐26 positions

2019 ◽  
Vol 94 (4) ◽  
pp. 1859-1864 ◽  
Author(s):  
Greta Klejborowska ◽  
Marta Jędrzejczyk ◽  
Natalia Stępczyńska ◽  
Ewa Maj ◽  
Joanna Wietrzyk ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Monensin A ◽  
Derivatives Of

One‐pot synthesis and antiproliferative activity of novel double‐modified derivatives of the polyether ionophore monensin A

2018 ◽  
Vol 92 (2) ◽  
pp. 1537-1546 ◽  
Author(s):  
Greta Klejborowska ◽  
Ewa Maj ◽  
Joanna Wietrzyk ◽  
Joanna Stefańska ◽  
Adam Huczyński
Keyword(s):  
Antiproliferative Activity ◽  
One Pot ◽  
One Pot Synthesis ◽  
Monensin A ◽  
Derivatives Of ◽  
Ionophore Monensin

scholarly journals Synthesis, Antiproliferative Activity and Radical Scavenging Ability of 5-O-Acyl Derivatives of Quercetin

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1608
Author(s):  
Stephen Lo ◽  
Euphemia Leung ◽  
Bruno Fedrizzi ◽  
David Barker
Keyword(s):  
Antiproliferative Activity ◽  
Biological Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Breast Cancer Cell Lines ◽  
Scavenging Activity ◽  
Plant Materials ◽  
Wide Range ◽  
Derivatives Of ◽  
Acyl Derivatives

Quercetin is a flavonoid that is found in many plant materials, including commonly eaten fruits and vegetables. The compound is well known for its wide range of biological activities. In this study, 5-O-acyl derivatives of quercetin were synthesised and assessed for their antiproliferative activity against the HCT116 colon cancer and MDA-MB-231 breast cancer cell lines; and their radical scavenging activity against the 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical species. Four derivatives were found to have improved the antiproliferative activity compared to quercetin whilst retaining radical scavenging activity.

Synthesis and evaluation of the antiproliferative activity of new heterylmethylidene derivatives of imidazothiazolotriazinones

2021 ◽  
Author(s):  
Alexei N. Izmest'ev ◽  
Galina A. Gazieva ◽  
Lada V. Anikina ◽  
Sergey A. Pukhov ◽  
Valentina A. Karnoukhova ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Derivatives Of

Two series of regioisomeric heterylmethylidene derivatives of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazines and imidazo[4,5-e]thiazolo[2,3-c]-1,2,4-triazines were synthesized. Several compounds exhibiting high antiproliferative activity were found.

scholarly journals New Acetylenic Amine Derivatives of 5,8-Quinolinediones: Synthesis, Crystal Structure and Antiproliferative Activity

Crystals ◽  
2017 ◽  
Vol 7 (1) ◽  
pp. 15 ◽  
Author(s):  
Monika Kadela-Tomanek ◽  
Maria Jastrzębska ◽  
Ewa Bębenek ◽  
Elwira Chrobak ◽  
Małgorzata Latocha ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Antiproliferative Activity ◽  
Acetylenic Amine ◽  
Derivatives Of

Synthesis and antiproliferative activity of C-homo-lactam derivatives of 7-deoxycholic acid

2013 ◽  
Vol 23 (7) ◽  
pp. 2265-2267 ◽  
Author(s):  
Yanmin Huang ◽  
Jianguo Cui ◽  
Sijing Chen ◽  
Chunfang Gan ◽  
Qiucui Yao ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Deoxycholic Acid ◽  
Derivatives Of

Syntheses of lactam derivatives of chenodeoxycholic acid and in vitro antiproliferative activity

2014 ◽  
Vol 30 (4) ◽  
pp. 605-613 ◽  
Author(s):  
Yanmin Huang ◽  
Qiucui Yao ◽  
Jianguo Cui ◽  
Chunfang Gan ◽  
Qianyang Huang ◽  
...  
Keyword(s):  
Chenodeoxycholic Acid ◽  
Antiproliferative Activity ◽  
Derivatives Of
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