Design, Synthesis, and Biological Evaluation of a Novel Water-soluble Prodrug of Docetaxel with Amino Acid as a Linker

Huan Ma; Gang Chen; Tao Wang; Qingeng Li; Yan Liu

doi:10.1111/cbdd.12762

Design, Synthesis, and Biological Evaluation of a Novel Water-soluble Prodrug of Docetaxel with Amino Acid as a Linker

Chemical Biology & Drug Design ◽

10.1111/cbdd.12762 ◽

2016 ◽

Vol 88 (3) ◽

pp. 363-369 ◽

Cited By ~ 4

Author(s):

Huan Ma ◽

Gang Chen ◽

Tao Wang ◽

Qingeng Li ◽

Yan Liu

Keyword(s):

Amino Acid ◽

Biological Evaluation ◽

Water Soluble ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2016.01.007 ◽

2016 ◽

Vol 24 (5) ◽

pp. 938-956 ◽

Cited By ~ 23

Author(s):

Laxman Devkota ◽

Chen-Ming Lin ◽

Tracy E. Strecker ◽

Yifan Wang ◽

Justin K. Tidmore ◽

...

Keyword(s):

Amino Acid ◽

Biological Evaluation ◽

Water Soluble ◽

Vascular Disrupting Agents ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Vascular Disrupting

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Abstract 284: Design, synthesis and biological evaluation of novel water-soluble salts of the antimitotic prodrugs 4-(3-alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamides selectively bioactivated by cytochrome p450 1A1 in breast cancer cells

10.1158/1538-7445.am2021-284 ◽

2021 ◽

Author(s):

Vincent Ouellette ◽

Atziri Corin Chavez Alvarez ◽

Sébastien Fortin

Keyword(s):

Breast Cancer ◽

Cytochrome P450 ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Biological Evaluation ◽

Water Soluble ◽

Soluble Salts ◽

Cytochrome P450 1A1 ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel tripeptidyl epoxyketone derivatives constructed from β-amino acid as proteasome inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.04.011 ◽

2014 ◽

Vol 22 (11) ◽

pp. 2955-2965 ◽

Cited By ~ 4

Author(s):

Jiankang Zhang ◽

Jiayi Cao ◽

Lei Xu ◽

Yubo Zhou ◽

Tao Liu ◽

...

Keyword(s):

Amino Acid ◽

Proteasome Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of water-soluble per-O-methylated cyclodextrin-C60 conjugates as anti-influenza virus agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.01.040 ◽

2018 ◽

Vol 146 ◽

pp. 194-205 ◽

Cited By ~ 9

Author(s):

Xiaolei Zhu ◽

Sulong Xiao ◽

Demin Zhou ◽

Matthieu Sollogoub ◽

Yongmin Zhang

Keyword(s):

Influenza Virus ◽

Biological Evaluation ◽

Water Soluble ◽

Design Synthesis ◽

Methylated Cyclodextrin ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of novel water-soluble triptolide derivatives: Antineoplastic activity against imatinib-resistant CML cells bearing T315I mutant Bcr-Abl

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2010.01.052 ◽

2010 ◽

Vol 18 (5) ◽

pp. 1806-1815 ◽

Cited By ~ 13

Author(s):

Fang Xu ◽

Xianping Shi ◽

Shichang Li ◽

Jieshun Cui ◽

Zhongzheng Lu ◽

...

Keyword(s):

Biological Evaluation ◽

Water Soluble ◽

Antineoplastic Activity ◽

Design Synthesis ◽

Imatinib Resistant ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2016.09.027 ◽

2016 ◽

Vol 26 (21) ◽

pp. 5340-5345 ◽

Cited By ~ 7

Author(s):

Tony D. Davis ◽

Poornima Mohandas ◽

Maria I. Chiriac ◽

Glennon V. Bythrow ◽

Luis E.N. Quadri ◽

...

Keyword(s):

Amino Acid ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2010.11.005 ◽

2011 ◽

Vol 19 (1) ◽

pp. 471-485 ◽

Cited By ~ 15

Author(s):

Naval Kapuriya ◽

Rajesh Kakadiya ◽

Huajin Dong ◽

Amit Kumar ◽

Pei-Chih Lee ◽

...

Keyword(s):

Anticancer Agents ◽

Biological Evaluation ◽

Water Soluble ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of target water‐soluble hydroxamic acid‐based HDACi derivatives as prodrugs

Chemical Biology & Drug Design ◽

10.1111/cbdd.13577 ◽

2019 ◽

Vol 94 (4) ◽

pp. 1760-1767 ◽

Cited By ~ 3

Author(s):

Jun Li ◽

Yedan Zhu ◽

Miaohong Xie ◽

Qian Zhang ◽

Wenting Du

Keyword(s):

Hydroxamic Acid ◽

Biological Evaluation ◽

Water Soluble ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of a highly water-soluble psoralen-based photosensitizer

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.02.050 ◽

2017 ◽

Vol 25 (8) ◽

pp. 2372-2377 ◽

Cited By ~ 5

Author(s):

Yoshiyuki Uruma ◽

Takuya Nonomura ◽

Priscilla Yoong Mei Yen ◽

Marie Edatani ◽

Ryotaro Yamamoto ◽

...

Keyword(s):

Biological Evaluation ◽

Water Soluble ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of novel 4-anilinoquinazoline derivatives bearing amino acid moiety as potential EGFR kinase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.02.061 ◽

2017 ◽

Vol 130 ◽

pp. 393-405 ◽

Cited By ~ 9

Author(s):

You-Guang Zheng ◽

Jun Su ◽

Cai-Yun Gao ◽

Ping Jiang ◽

Lin An ◽

...

Keyword(s):

Amino Acid ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Acid Moiety ◽

Design Synthesis ◽

Amino Acid Moiety ◽

Synthesis And Biological Evaluation ◽

Egfr Kinase

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