Ternary Dinuclear Copper(II) Complexes of a Reduced Schiff Base Ligand with Diimine Coligands: DNA Binding, Cytotoxic Cell Apoptosis, and Apoptotic Mechanism

2015 ◽  
Vol 87 (3) ◽  
pp. 398-408 ◽  
Author(s):  
Hao Yu ◽  
Yong Yang ◽  
Qiaoyu Li ◽  
Tieliang Ma ◽  
Jun Xu ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Schiff Base Ligand ◽  
Cell Apoptosis ◽  
Dinuclear Copper ◽  
Cytotoxic Cell ◽  
Reduced Schiff Base ◽  
Apoptotic Mechanism

scholarly journals Yb(III), Sm(III) and La(III) complexes of a tetradentate pyridoxal Schiff base ligand: Their DNA-binding activity and bio-imaging applications

Polyhedron ◽  
2020 ◽  
Vol 175 ◽  
pp. 114167
Author(s):  
Moumita Chakraborty ◽  
Satyajit Mondal ◽  
Christine Cardin ◽  
Arnold L. Rheingold ◽  
Chitrangada Das Mukhopadhyay ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Schiff Base Ligand ◽  
Binding Activity ◽  
Dna Binding Activity ◽  
Bio Imaging

scholarly journals Copper(ii) complexes based on quinoline-derived Schiff-base ligands: synthesis, characterization, HSA/DNA binding ability, and anticancer activity

MedChemComm ◽  
2018 ◽  
Vol 9 (10) ◽  
pp. 1663-1672 ◽  
Author(s):  
Kun Hu ◽  
Chensi Liu ◽  
Jingui Li ◽  
Fupei Liang
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Tumor Cell ◽  
Anticancer Activity ◽  
Hela Cells ◽  
Cell Apoptosis ◽  
Schiff Base Ligands ◽  
Binding Ability ◽  
Tumor Cell Apoptosis ◽  
Cell Cycles

Three Cu(ii) complexes (C1–C3) were designed and synthesized.C3, in particular, having a ligand derived from benzocaine, exhibited greater selectivity toward HeLa cells, arrested cell cycles, and promoted tumor cell apoptosis.

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