scholarly journals SCTR hypermethylation is a diagnostic biomarker in colorectal cancer

2020 ◽  
Vol 111 (12) ◽  
pp. 4558-4566
Author(s):  
DaPeng Li ◽  
Lei Zhang ◽  
JinMing Fu ◽  
Hao Huang ◽  
SiMin Sun ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Diagnostic Biomarker

Long noncoding RNA LINC00978 acts as a potential diagnostic biomarker in patients with colorectal cancer

2021 ◽  
pp. 104666
Author(s):  
Majid Ghasemian ◽  
Masoumeh Rajabibazl ◽  
Reza Mirfakhraie ◽  
Amirnader Emami Razavi ◽  
Hossein Sadeghi
Keyword(s):  
Colorectal Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Diagnostic Biomarker

Serum Macrophage Inhibitory Cytokine-1 Serves as a Novel Diagnostic Biomarker of Early-Stage Colorectal Cancer

Biomarkers ◽  
2021 ◽  
pp. 1-21
Author(s):  
Chunyang Dai ◽  
Xiaolei Zhang ◽  
Yanling Ma ◽  
Zhaowu Chen ◽  
Shaohua Chen ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Early Stage ◽  
Diagnostic Biomarker

scholarly journals Role of microsatellite instability-low as a diagnostic biomarker of Lynch syndrome in colorectal cancer

2014 ◽  
Vol 207 (10-12) ◽  
pp. 495-502 ◽  
Author(s):  
Eduardo Vilar ◽  
Maureen E. Mork ◽  
Amanda Cuddy ◽  
Ester Borras ◽  
Sarah A. Bannon ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lynch Syndrome ◽  
Microsatellite Instability ◽  
Diagnostic Biomarker

scholarly journals A Review of the Role of Neurotensin and Its Receptors in Colorectal Cancer

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Shengyang Qiu ◽  
Gianluca Pellino ◽  
Francesca Fiorentino ◽  
Shahnawaz Rasheed ◽  
Ara Darzi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Animal Studies ◽  
In Vivo Studies ◽  
Signalling Pathways ◽  
Diagnostic Biomarker ◽  
Gi Tract ◽  
Cellular Receptors

Neurotensin (NTS) is a physiologically occurring hormone which affects the function of the gastrointestinal (GI) tract. In recent years, NTS, acting through its cellular receptors (NTSR), has been implicated in the carcinogenesis of several cancers. In colorectal cancer (CRC), a significant body of evidence, from in vitro and in vivo studies, is available which elucidates the molecular biology of NTS/NTSR signalling and the resultant growth of CRC cells. There is growing clinical data from human studies which corroborate the role NTS/NTSR plays in the development of human CRC. Furthermore, blockade and modulation of the NTS/NTSR signalling pathways appears to reduce CRC growth in cell cultures and animal studies. Lastly, NTS/NTSR also shows potential of being utilised as a diagnostic biomarker for cancers as well as targets for functional imaging. We summarise the existing evidence and understanding of the role of NTS and its receptors in CRC.

Altered plasma levels of decanoic acid in colorectal cancer as a new diagnostic biomarker

2016 ◽  
Vol 408 (23) ◽  
pp. 6321-6328 ◽  
Author(s):  
Sara Crotti ◽  
Elisa Agnoletto ◽  
Gabriella Cancemi ◽  
Valerio Di Marco ◽  
Pietro Traldi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Plasma Levels ◽  
Decanoic Acid ◽  
Diagnostic Biomarker

scholarly journals Circulating miR-338-5p is a potential diagnostic biomarker in colorectal cancer

2018 ◽  
Vol 19 (7) ◽  
pp. 404-410 ◽  
Author(s):  
Enkhnaran Bilegsaikhan ◽  
Hai Ning Liu ◽  
Xi Zhong Shen ◽  
Tao Tao Liu
Keyword(s):  
Colorectal Cancer ◽  
Diagnostic Biomarker

scholarly journals Gut Microbiota Profiles in Early- and Late-Onset Colorectal Cancer: A Potential Diagnostic Biomarker in the Future

Digestion ◽  
2021 ◽  
pp. 1-10
Author(s):  
Murdani Abdullah ◽  
Ninik Sukartini ◽  
Saskia Aziza Nursyirwan ◽  
Rabbinu Rangga Pribadi ◽  
Hasan Maulahela ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Gut Microbiota ◽  
Late Onset ◽  
Diagnostic Biomarker ◽  
Incidence And Mortality ◽  
The Future ◽  
Early Onset Colorectal Cancer ◽  
Gut Microbiota Dysbiosis

<b><i>Background:</i></b> Researchers believe the role of gut microbiota dysbiosis in the raised incidence of early-onset colorectal cancer (EOCRC). The development of EOCRC may be associated with microbiota dysbiosis either dependently or independently (combined with other risk factors). <b><i>Summary:</i></b> Recently, the rising of incidence and mortality of EOCRC have been noted. Some researchers are looking for risk factors influencing this fact. They hypothesize that it may be because of microbiota dysbiosis. Microbiota dysbiosis has been known to promote cancer development through immunity dysregulation and chronic inflammation. Microbiomes profile in late-onset colorectal cancer (LOCRC) among older patients has been documented, but there is still lack of data about microbial profiles among younger colorectal cancer (CRC) patients. This review tries to explain microbial profiles differences between EOCRC and LOCRC as a potential diagnostic biomarker in the future, and whether microbiota can have a role in EOCRC genesis. <b><i>Key Messages:</i></b> Microbiota does vary with age, and EOCRC may be associated with colonization of some specific bacteria. Further studies about gut microbiota profiles in EOCRC and LOCRC may provide a new insight on diagnostic biomarker of CRC.

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