scholarly journals Thymidylate synthase inhibitor raltitrexed can induce high levels of DNA damage in MYCN ‐amplified neuroblastoma cells

2020 ◽  
Vol 111 (7) ◽  
pp. 2431-2439
Author(s):  
Ken Yamashita ◽  
Shinichi Kiyonari ◽  
Shoma Tsubota ◽  
Satoshi Kishida ◽  
Ryuichi Sakai ◽  
...  
Keyword(s):  
Dna Damage ◽  
Thymidylate Synthase ◽  
Neuroblastoma Cells ◽  
Thymidylate Synthase Inhibitor ◽  
Synthase Inhibitor

scholarly journals Phase I, Pharmacokinetic and Biological Correlative Study of OSI-7904L, a Novel Liposomal Thymidylate Synthase Inhibitor, and Cisplatin in Patients with Solid Tumors

2008 ◽  
Vol 14 (23) ◽  
pp. 7947-7955 ◽  
Author(s):  
Alejandro D. Ricart ◽  
Jordan D. Berlin ◽  
Kyriakos P. Papadopoulos ◽  
Samira Syed ◽  
Daniel W. Drolet ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Thymidylate Synthase ◽  
Correlative Study ◽  
Thymidylate Synthase Inhibitor ◽  
Synthase Inhibitor

New Synthesis of Thymidylate Synthase Inhibitor Raltitrexed

2003 ◽  
Vol 33 (20) ◽  
pp. 3519-3526 ◽  
Author(s):  
Sheng-Li Cao ◽  
Rong Wan ◽  
Yu-Ping Feng
Keyword(s):  
Thymidylate Synthase ◽  
New Synthesis ◽  
Thymidylate Synthase Inhibitor ◽  
Synthase Inhibitor

scholarly journals BGC 945, a Novel Tumor-Selective Thymidylate Synthase Inhibitor Targeted to α-Folate Receptor–Overexpressing Tumors

2005 ◽  
Vol 65 (24) ◽  
pp. 11721-11728 ◽  
Author(s):  
David D. Gibbs ◽  
Davinder S. Theti ◽  
Nadya Wood ◽  
Matthew Green ◽  
Florence Raynaud ◽  
...  
Keyword(s):  
Thymidylate Synthase ◽  
Folate Receptor ◽  
Thymidylate Synthase Inhibitor ◽  
Synthase Inhibitor ◽  
Tumor Selective
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