Novel p97/
            VCP
            inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib‐sensitive and ‐resistant multiple myeloma cells

Nao Nishimura; Mohamed O. Radwan; Masayuki Amano; Shinya Endo; Eri Fujii; Hironori Hayashi; Shikiko Ueno; Niina Ueno; Hiro Tatetsu; Hiroyuki Hata; Yoshinari Okamoto; Masami Otsuka; Hiroaki Mitsuya; Masao Matsuoka; Yutaka Okuno

doi:10.1111/cas.14154

Novel p97/ VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib‐sensitive and ‐resistant multiple myeloma cells

Cancer Science ◽

10.1111/cas.14154 ◽

2019 ◽

Vol 110 (10) ◽

pp. 3275-3287 ◽

Cited By ~ 5

Author(s):

Nao Nishimura ◽

Mohamed O. Radwan ◽

Masayuki Amano ◽

Shinya Endo ◽

Eri Fujii ◽

...

Keyword(s):

Multiple Myeloma ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Myeloma Cells

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Combined therapeutic effects of bortezomib and anacardic acid on multiple myeloma cells via activation of the endoplasmic reticulum stress response

Molecular Medicine Reports ◽

10.3892/mmr.2016.5533 ◽

2016 ◽

Vol 14 (3) ◽

pp. 2679-2684 ◽

Cited By ~ 1

Author(s):

Xiaoxian Dong ◽

Yuning Liao ◽

Ningning Liu ◽

Xianliang Hua ◽

Jianyu Cai ◽

...

Keyword(s):

Multiple Myeloma ◽

Endoplasmic Reticulum ◽

Stress Response ◽

Endoplasmic Reticulum Stress ◽

Anacardic Acid ◽

Endoplasmic Reticulum Stress Response ◽

Therapeutic Effects ◽

Myeloma Cells

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Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

International Journal of Molecular Sciences ◽

10.3390/ijms19010277 ◽

2018 ◽

Vol 19 (1) ◽

pp. 277 ◽

Cited By ~ 3

Author(s):

Thomas Chen ◽

Nymph Chan ◽

Shirin Labib ◽

Jiali Yu ◽

Hee-Yeon Cho ◽

...

Keyword(s):

Multiple Myeloma ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Perillyl Alcohol ◽

Myeloma Cells

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Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells

Experimental Hematology ◽

10.1016/j.exphem.2011.06.007 ◽

2011 ◽

Vol 39 (10) ◽

pp. 999-1006 ◽

Cited By ~ 45

Author(s):

Feng-Ming Wang ◽

Deborah L. Galson ◽

G. David Roodman ◽

Hongjiao Ouyang

Keyword(s):

Multiple Myeloma ◽

Endoplasmic Reticulum ◽

Stress Response ◽

Endoplasmic Reticulum Stress ◽

Endoplasmic Reticulum Stress Response ◽

Myeloma Cells ◽

Human Multiple Myeloma

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Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells

Oncotarget ◽

10.18632/oncotarget.12060 ◽

2016 ◽

Vol 7 (43) ◽

pp. 70546-70558 ◽

Cited By ~ 12

Author(s):

Valeria Catena ◽

Tiziana Bruno ◽

Francesca De Nicola ◽

Frauke Goeman ◽

Matteo Pallocca ◽

...

Keyword(s):

Multiple Myeloma ◽

Endoplasmic Reticulum ◽

Myeloma Cells

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Endoplasmic Reticulum Stress and the Unfolded Protein Response: Targeting the Achilles Heel of Multiple Myeloma

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-12-0782 ◽

2013 ◽

Vol 12 (6) ◽

pp. 831-843 ◽

Cited By ~ 89

Author(s):

Lisa Vincenz ◽

Richard Jäger ◽

Michael O'Dwyer ◽

Afshin Samali

Keyword(s):

Multiple Myeloma ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Unfolded Protein Response ◽

Unfolded Protein ◽

The Unfolded Protein Response ◽

Protein Response

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Toll-Like Receptor 4 Activation Promotes Multiple Myeloma Cell Growth and Survival Via Suppression of The Endoplasmic Reticulum Stress Factor Chop

Scientific Reports ◽

10.1038/s41598-019-39672-7 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 8

Author(s):

Tina Bagratuni ◽

Aimilia D. Sklirou ◽

Efstathios Kastritis ◽

Christine Ivy Liacos ◽

Christina Spilioti ◽

...

Keyword(s):

Multiple Myeloma ◽

Endoplasmic Reticulum ◽

Cell Growth ◽

Endoplasmic Reticulum Stress ◽

Myeloma Cell ◽

Stress Factor ◽

Toll Like Receptor ◽

Toll Like Receptor 4 ◽

Growth And Survival ◽

Multiple Myeloma Cell

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Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells

International Journal of Oncology ◽

10.3892/ijo.2013.1870 ◽

2013 ◽

Vol 42 (5) ◽

pp. 1541-1550 ◽

Cited By ~ 47

Author(s):

SHOTA MORIYA ◽

XIAO-FANG CHE ◽

SEIICHIRO KOMATSU ◽

AKIHISA ABE ◽

TOMOHIRO KAWAGUCHI ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Macrolide Antibiotics ◽

Autophagy Flux ◽

Myeloma Cells

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Combined treatment with bortezomib plus bafilomycin A1 enhances the cytocidal effect and induces endoplasmic reticulum stress in U266 myeloma cells: Crosstalk among proteasome, autophagy-lysosome and ER stress

International Journal of Oncology ◽

10.3892/ijo.2010.882 ◽

2011 ◽

Vol 38 (3) ◽

Cited By ~ 9

Author(s):

Miyazawa

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Er Stress ◽

Combined Treatment ◽

Bafilomycin A1 ◽

Myeloma Cells ◽

Cytocidal Effect

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High NRF2 expression controls endoplasmic reticulum stress induced apoptosis in multiple myeloma

Cancer Letters ◽

10.1016/j.canlet.2017.10.005 ◽

2018 ◽

Vol 412 ◽

pp. 37-45 ◽

Cited By ~ 12

Author(s):

Yu Sun ◽

Amina Abdul Aziz ◽

Kristian Bowles ◽

Stuart Rushworth

Keyword(s):

Multiple Myeloma ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Induced Apoptosis ◽

Nrf2 Expression

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Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells

Leukemia & Lymphoma ◽

10.1080/10428190500312196 ◽

2006 ◽

Vol 47 (3) ◽

pp. 531-539 ◽

Cited By ~ 42

Author(s):

Miki Nakamura ◽

Tomomi Gotoh ◽

Yutaka Okuno ◽

Hiro Tatetsu ◽

Takashi Sonoki ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Myeloma Cells ◽

Endoplasmic Reticulum Stress Pathway ◽

Stress Pathway

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