scholarly journals Prognostic significance of CD 169‐positive lymph node sinus macrophages in patients with endometrial carcinoma

2016 ◽  
Vol 107 (6) ◽  
pp. 846-852 ◽  
Author(s):  
Koji Ohnishi ◽  
Munekage Yamaguchi ◽  
Chimeddulam Erdenebaatar ◽  
Fumitaka Saito ◽  
Hironori Tashiro ◽  
...  
Keyword(s):  
Lymph Node ◽  
Endometrial Carcinoma ◽  
Prognostic Significance ◽  
Positive Lymph Node ◽  
Lymph Node Sinus

Prognostic Significance of Progesterone Receptor Immunohistochemistry for Lymph Node Metastases in Endometrial Carcinoma

1999 ◽  
Vol 72 (3) ◽  
pp. 351-359 ◽  
Author(s):  
Kyoko Iwai ◽  
Koichi Fukuda ◽  
Toru Hachisuga ◽  
Mitsuru Mori ◽  
Michiko Uchiyama ◽  
...  
Keyword(s):  
Lymph Node ◽  
Progesterone Receptor ◽  
Endometrial Carcinoma ◽  
Lymph Node Metastases ◽  
Prognostic Significance ◽  
Node Metastases

scholarly journals Diagnostic Significance of Serum Eotaxin-1 Level in Gastric Cancer Patients

2013 ◽  
Vol 35 ◽  
pp. 363-367 ◽  
Author(s):  
Ümit Koç ◽  
Erdinç Çetinkaya ◽  
Erdal B. Bostanci ◽  
Ahu S. Kemık ◽  
Mesut Tez ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Inflammatory Diseases ◽  
Prognostic Significance ◽  
Delayed Diagnosis ◽  
Positive Lymph Node ◽  
Diagnostic Significance ◽  
Number Of Patients ◽  
Gastric Cancer Patients

Introduction. Gastric cancer is the second cause of cancer-related deaths worldwide. Delayed diagnosis leads to high mortality rates. Eotaxin-1 was originally discovered as an eosinophil-selective chemoattractant and may play a role in a number of chronic inflammatory diseases, cancer, and other gastrointestinal disorders. The aim of this study was to analyse diagnostic and prognostic significance of serum eotaxin-1 (s-eotaxin-1) levels in gastric cancer.Methods. Sixty gastric cancer patients and 69 healthy subjects were included into the study. S-eotaxin-1 levels were compared with clinicopathological features and outcomes in gastric cancer.Results. Serum levels of eotaxin-1 in gastric cancer patients were significantly higher than controls ( pg/mL versus  pg/mL, respectively ()). The s-eotaxin-1 levels did not differ significantly with histopathological grade, tumor-node-metastasis (TNM) stage, tumor localization, lymph node metastases, positive lymph node ratio, size, perineural and perivascular invasion. So there is no relationship found between s-eotaxin-1 level and prognosis.Conclusion. S-eotaxin-1 levels may be used as an easily available biomarker for gastric cancer risk and may alert physicians for early diagnosis. Due to the limited number of patients included in this study, larger cohort studies are warranted to validate the diagnostic value of s-eotaxin-1 level in gastric cancer.

Prognostic significance of Bcl-2, p53 overexpression, and lymph node metastasis in surgically staged endometrial carcinoma

2002 ◽  
Vol 187 (2) ◽  
pp. 353-359 ◽  
Author(s):  
Toshihiro Ohkouchi ◽  
Noriaki Sakuragi ◽  
Hidemichi Watari ◽  
Eiji Nomura ◽  
Yukiharu Todo ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Endometrial Carcinoma ◽  
Prognostic Significance ◽  
P53 Overexpression ◽  
Node Metastasis

scholarly journals Prognostic significance of positive lymph node ratio in patients with pN3 gastric cancer who underwent curative gastrectomy

2017 ◽  
Vol 28 ◽  
pp. iii35-iii36
Author(s):  
Ahmet Bilici ◽  
Mesut Seker ◽  
Basak Oven Ustaalioglu Bala ◽  
Fatih Olmez Omer ◽  
Ozcan Yildiz ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Ratio ◽  
Prognostic Significance ◽  
Positive Lymph Node ◽  
Curative Gastrectomy ◽  
Node Ratio

Prognostic Significance of CD169+ Lymph Node Sinus Macrophages in Patients with Malignant Melanoma

2015 ◽  
Vol 3 (12) ◽  
pp. 1356-1363 ◽  
Author(s):  
Yoichi Saito ◽  
Koji Ohnishi ◽  
Azusa Miyashita ◽  
Satoshi Nakahara ◽  
Yukio Fujiwara ◽  
...  
Keyword(s):  
Lymph Node ◽  
Malignant Melanoma ◽  
Prognostic Significance ◽  
Lymph Node Sinus

Prognostic significance of positive lymph node ratio in resected esophageal cancer.

2011 ◽  
Vol 29 (4_suppl) ◽  
pp. 100-100 ◽  
Author(s):  
R. Thota ◽  
T. Tashi ◽  
W. Gonsalves ◽  
A. R. Sama ◽  
P. T. Silberstein ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Lymph Node Ratio ◽  
Prognostic Significance ◽  
Positive Lymph Node ◽  
Muscularis Mucosa ◽  
Multicenter Studies ◽  
Node Ratio ◽  
Positive Lymph Nodes

100 Background: Nodal involvement in esophageal cancer is associated with poor survival. We aim to determine whether the ratio of metastatic to examined lymph nodes (the lymph node ratio [LNR]) is a better predictor of survival as compared to the number of positive lymph nodes in resected esophageal cancer. Methods: 1,149 patients with resected esophageal cancer from 1995 to 2009 were identified from the VA Central Cancer Registry (VACCR) database. The patients were further characterized to 3 lymph node quartiles based on LNR and their median survivals were calculated using the Kaplan-Meier method. Results: Out of 1149 patients 26.4% patients (303) had squamous cell carcinoma and 73.6% (846) were of adenocarcinoma histology. Median age of diagnosis is 63 years. 353 (31%) are stage 1, 384 (33%) are stage 2, and 412 (36%) are stage 3. Majority of them 71% arise in lower third of esophagus followed by 13% in middle third, 4% in upper third and 12 % had unknown site of origin. The group was subdivided into 3 quartiles with 62.7% in LNR1 (0.0-0.1), 25.6% in LNR2 (0.1-0.5) and 11.7% in LNR3 (0.5-1.0). 13.7% had less than 2 nodes removed, 29.3% had 3-6 nodes and 57% had >7 nodes examined. 28% of them had tumor invading sub mucosa, 23.5% had tumor invading muscularis mucosa, 43.2% had involvement of adventitia and 5.3% had penetrating tumor at the time of diagnosis The 5 year survivals based on number of lymph nodes examined, number of positive lymph nodes and positive lymph node ratio are listed in the table. The median overall survival for resected esophageal cancer based on LNR quartiles was 37 vs 14 vs 11.5 months (p<0.0001). Conclusions: Number of positive lymph nodes and positive lymph node ratio correlated with survival outcomes but number of lymph nodes retrieved did not predict any survival differences. However LNR was a better predictor of survival when compared to number of positive nodes. Further validation of this observation needs to done in large multicenter studies. [Table: see text] No significant financial relationships to disclose.

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