Emerging role of cysteinyl leukotrienes in cancer

2021 ◽  
Author(s):  
Lou Saier ◽  
Olivier Peyruchaud
Keyword(s):  
Cysteinyl Leukotrienes

The role of Cysteinyl-Leukotrienes in preeclamptic patients

2021 ◽  
Author(s):  
H Jaksch-Bogensperger ◽  
A Koller ◽  
Th Fischer ◽  
L Aigner ◽  
C Fazelnia ◽  
...  
Keyword(s):  
Cysteinyl Leukotrienes

scholarly journals Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases

2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
Francesca Colazzo ◽  
Paolo Gelosa ◽  
Elena Tremoli ◽  
Luigi Sironi ◽  
Laura Castiglioni
Keyword(s):  
Myocardial Infarction ◽  
Cardiovascular Diseases ◽  
Inflammatory Diseases ◽  
Asthma Management ◽  
Cardiovascular Disorders ◽  
Cysteinyl Leukotrienes ◽  
Pathway Activation ◽  
Cardioprotective Effects ◽  
Progression Of Atherosclerosis

Cysteinyl leukotrienes (CysLTs) are potent lipid inflammatory mediators synthesized from arachidonic acid, through the 5-lipoxygenase (5-LO) pathway. Owing to their properties, CysLTs play a crucial role in the pathogenesis of inflammation; therefore, CysLT modifiers as synthesis inhibitors or receptor antagonists, central in asthma management, may become a potential target for the treatment of other inflammatory diseases such as the cardiovascular disorders. 5-LO pathway activation and increased expression of its mediators and receptors are found in cardiovascular diseases. Moreover, the cardioprotective effects observed by using CysLT modifiers are promising and contribute to elucidate the link between CysLTs and cardiovascular disease. The aim of this review is to summarize the state of present research about the role of the CysLTs in the pathogenesis and progression of atherosclerosis and myocardial infarction.

scholarly journals The role of cysteinyl leukotrienes on lipopolysaccharide-induced bronchial hyperresponsiveness in guinea pigs

1996 ◽  
Vol 71 ◽  
pp. 305
Author(s):  
Takashi Uno ◽  
Hiroyuki Tanaka ◽  
Yoshizou Maeda ◽  
Akifumi Kogame ◽  
Hiroichi Nagai
Keyword(s):  
Guinea Pigs ◽  
Bronchial Hyperresponsiveness ◽  
Cysteinyl Leukotrienes

scholarly journals Role of cysteinyl-leukotrienes for portal pressure regulation and liver damage in cholestatic rat livers

2013 ◽  
Vol 93 (12) ◽  
pp. 1288-1294 ◽  
Author(s):  
Mark op den Winkel ◽  
Leonore Gmelin ◽  
Julia Schewe ◽  
Natalie Leistner ◽  
Manfred Bilzer ◽  
...  
Keyword(s):  
Liver Damage ◽  
Portal Pressure ◽  
Pressure Regulation ◽  
Cysteinyl Leukotrienes ◽  
Rat Livers

scholarly journals Inflammatory Role of Cysteinyl Leukotrienes in Human Vascular Endothelial Cells

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Ernest Duah ◽  
Vinay Kondeti ◽  
Ravi K Adapala ◽  
Joel Sanford ◽  
Charles K Thodeti ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Cysteinyl Leukotrienes
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