scholarly journals A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K

2015 ◽  
Vol 173 (2) ◽  
pp. 396-410 ◽  
Author(s):  
Preety Panwar ◽  
Kent Søe ◽  
Rafael VC Guido ◽  
Renata V C Bueno ◽  
Jean-Marie Delaisse ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Cathepsin K ◽  
Inhibit Bone Resorption ◽  
Novel Approach

scholarly journals Peptide Aldehyde Inhibitors of Cathepsin K Inhibit Bone Resorption Both In Vitro and In Vivo

1997 ◽  
Vol 12 (9) ◽  
pp. 1396-1406 ◽  
Author(s):  
Bartholomew J. Votta ◽  
Mark A. Levy ◽  
Alison Badger ◽  
Jeremy Bradbeer ◽  
Robert A. Dodds ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Cathepsin K ◽  
Inhibit Bone Resorption

A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys

Bone ◽  
2007 ◽  
Vol 40 (1) ◽  
pp. 122-131 ◽  
Author(s):  
S. Kumar ◽  
L. Dare ◽  
J.A. Vasko-Moser ◽  
I.E. James ◽  
S.M. Blake ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Bone Turnover ◽  
Potent Inhibitor ◽  
Cathepsin K

Inhibition ofUlmus davidiana Planch (Ulmaceae) on bone resorption mediated by processing of Cathepsin K in cultured mouse osteoclasts

2008 ◽  
Vol 22 (4) ◽  
pp. 511-517 ◽  
Author(s):  
Kyung-Woon Kim ◽  
Jun-Sung Park ◽  
Kap-Sung Kim ◽  
Un-Ho Jin ◽  
June-Ki Kim ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Cathepsin K

Thiophene Compounds that Reduce Calculus Accumulation and Inhibit Bone Resorption

1975 ◽  
Vol 54 (2_suppl) ◽  
pp. 87-87 ◽  
Author(s):  
W. Lloyd ◽  
C. Minkin ◽  
M. Bresnahan ◽  
P. Baer ◽  
H. Wells
Keyword(s):  
Bone Resorption ◽  
Inhibit Bone Resorption

Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio

Bone ◽  
2005 ◽  
Vol 36 (1) ◽  
pp. 159-172 ◽  
Author(s):  
Riku Kiviranta ◽  
Jukka Morko ◽  
Sari L. Alatalo ◽  
Roisin NicAmhlaoibh ◽  
Juha Risteli ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Cathepsin K ◽  
Deficient Mice

scholarly journals Cathepsin K Antisense Oligodeoxynucleotide Inhibits Osteoclastic Bone Resorption

1997 ◽  
Vol 272 (13) ◽  
pp. 8109-8112 ◽  
Author(s):  
Takashi Inui ◽  
Osamu Ishibashi ◽  
Tetsuya Inaoka ◽  
Yumi Origane ◽  
Masayoshi Kumegawa ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Cathepsin K ◽  
Osteoclastic Bone Resorption ◽  
Antisense Oligodeoxynucleotide

scholarly journals Various Selected Vegetables, Fruits, Mushrooms and Red Wine Residue Inhibit Bone Resorption in Rats

2003 ◽  
Vol 133 (11) ◽  
pp. 3592-3597 ◽  
Author(s):  
Roman C. Mühlbauer ◽  
Annemarie Lozano ◽  
Andreas Reinli ◽  
Herbert Wetli
Keyword(s):  
Bone Resorption ◽  
Red Wine ◽  
Inhibit Bone Resorption
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