scholarly journals Overexpression of oxytocin receptors in the hypothalamic PVN increases baroreceptor reflex sensitivity and buffers BP variability in conscious rats

2014 ◽  
Vol 171 (19) ◽  
pp. 4385-4398 ◽  
Author(s):  
Maja Lozić ◽  
Michael Greenwood ◽  
Olivera Šarenac ◽  
Andrew Martin ◽  
Charles Hindmarch ◽  
...  
Keyword(s):  
Baroreceptor Reflex ◽  
Conscious Rats ◽  
Oxytocin Receptors ◽  
Baroreceptor Reflex Sensitivity

scholarly journals Dynamic Exercise Attenuates Spontaneous Baroreceptor Reflex Sensitivity in Conscious Rats

2003 ◽  
Vol 88 (4) ◽  
pp. 517-526 ◽  
Author(s):  
Hidefumi Waki ◽  
Sergey Kasparov ◽  
Kiyoaki Katahira ◽  
Tsuyoshi Shimizu ◽  
David Murphy ◽  
...  
Keyword(s):  
Baroreceptor Reflex ◽  
Dynamic Exercise ◽  
Conscious Rats ◽  
Baroreceptor Reflex Sensitivity

BP and HR Interactions: Assessment of Spontaneous Baroreceptor Reflex Sensitivity

2017 ◽  
pp. 199-226
Author(s):  
Tatjana Lončar-Turukalo ◽  
Nina Japundžić-Žigon ◽  
Olivera Šarenac ◽  
Dragana Bajić
Keyword(s):  
Baroreceptor Reflex ◽  
Baroreceptor Reflex Sensitivity

Role of nitric oxide in regulation of renal sympathetic nerve activity during hemorrhage in conscious rats

1999 ◽  
Vol 277 (1) ◽  
pp. H8-H14 ◽  
Author(s):  
Yoshihide Fujisawa ◽  
Naoko Mori ◽  
Kouichi Yube ◽  
Hiroshi Miyanaka ◽  
Akira Miyatake ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Saline Group ◽  
Baroreceptor Reflex ◽  
Nerve Activity ◽  
Renal Sympathetic Nerve Activity ◽  
Conscious Rats ◽  
Renal Sympathetic Nerve ◽  
Renal Sympathetic

The effect of inhibition of nitric oxide (NO) synthesis on the responses of blood pressure (BP), heart rate (HR), and renal sympathetic nerve activity (RSNA) during hemorrhaging was examined with the use of an NO synthase inhibitor, NG-nitro-l-arginine methyl ester (l-NAME), in conscious rats. In the 0.9% saline group, hemorrhage (10 ml/kg body wt) did not alter BP but significantly increased HR and RSNA by 88 ± 12 beats/min and 67 ± 12%, respectively. Intravenous infusion of l-NAME (50 μg ⋅ kg−1⋅ min−1) significantly attenuated these tachycardic and sympathoexcitatory responses to hemorrhage (14 ± 7 beats/min and 26 ± 12%, respectively). Pretreatment ofl-arginine (87 mg/kg) recovered the attenuation of HR and RSNA responses induced byl-NAME (92 ± 6 beats/min and 64 ± 10%, respectively).l-NAME by itself did not alter the baroreceptor reflex control of HR and RSNA. Hemorrhage increased the plasma vasopressin concentration, and its increment in thel-NAME-treated group was significantly higher than that in the 0.9% saline group. Pretreatment with the vascular arginine vasopressin V1-receptor antagonist OPC-21268 (5 mg/kg) recovered the attenuation of RSNA response induced byl-NAME (54 ± 7%). These results indicate that NO modulated HR and RSNA responses to hemorrhage but did not directly affect the baroreceptor reflex arch. It can be assumed that NO modulated the baroreflex function by altering the secretion of vasopressin induced by hemorrhage.

Atrial Natriuretic Factor in Central Cardiovascular Control

Physiology ◽  
1993 ◽  
Vol 8 (5) ◽  
pp. 223-228 ◽  
Author(s):  
S Oparil ◽  
JM Wyss
Keyword(s):  
Atrial Natriuretic Factor ◽  
Spontaneously Hypertensive Rat ◽  
Brain Regions ◽  
Baroreceptor Reflex ◽  
Hypothalamic Area ◽  
Spontaneously Hypertensive ◽  
Natriuretic Factor ◽  
Effector System ◽  
Baroreceptor Reflex Sensitivity ◽  
Atrial Natriuretic

A complete atrial natriuretic factor (ANF) synthetic, processing, and effector system is found in rat brain. ANF in critical brain regions, including anterior hypothalamic area and nucleus tractus solitarii, contributes importantly to the tonic control of blood pressure, sympathetic outflow, and baroreceptor reflex sensitivity in the spontaneously hypertensive rat.

scholarly journals Cardiovascular effects of reflexology in healthy individuals: evidence for a specific increase in blood pressure

2012 ◽  
Vol 2 (1) ◽  
pp. 4 ◽  
Author(s):  
Elisabeth Ruiz Padial ◽  
Nieves Torres López ◽  
Javier Luna Bujaldón ◽  
Isabel Espadas Villanueva ◽  
Gustavo Reyes del Paso
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Waiting Time ◽  
Healing Process ◽  
Cardiovascular Effects ◽  
Baroreceptor Reflex ◽  
Control Group ◽  
Time Control ◽  
Baroreceptor Reflex Sensitivity

The present study evaluates the cardiovascular effects of reflexology in a healthy sample. Forty-one participants were randomly assigned to one of three experimental groups: reflexology (n=15), non-professional foot massage (n=14), and a waiting time control group (n=12). Dependent variables were systolic, diastolic and mean blood pressure, inter-beat interval, heart rate variability and baroreceptor reflex sensitivity measured pre- and post- interventions. The study was performed during three 40-min sessions separated by weekly intervals. Results show that the three manipulations produce similar increases in inter-beat interval, heart rate variability and baroreceptor reflex sensitivity. Reflexology specifically produces an increase in blood pressure, which increases gradually over the three sessions. The parallel increase in heart rate variability and baroreceptor reflex sensitivity together with the increase in blood pressure suggest that reflexology is associated with a co-activation of both sympathetic and parasympathetic branches of the Autonomic Nervous System. These changes could be helpful in optimizing homeostatic activity, promoting the healing process and increasing the human organism’s capacity to respond adaptively to internal and external challenges. Finally, the observed physiological changes in the waiting-time control group shows the relevance of habituation processes and suggests the need for addition of waiting-time control groups in future studies.

Validation of spontaneous assessment of baroreceptor reflex sensitivity and its relation to heart rate variability in the ovine fetus pre- and near-term

2009 ◽  
Vol 87 (9) ◽  
pp. 736-742 ◽  
Author(s):  
Martin G. Frasch ◽  
Thomas Müller ◽  
Mark Szynkaruk ◽  
Matthias Schwab
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Reference Method ◽  
Baroreceptor Reflex ◽  
Vasoactive Drugs ◽  
Sequence Method ◽  
Baroreceptor Reflex Sensitivity ◽  
Ovine Fetus ◽  
Fetal Heart Rate Variability ◽  
Near Term

Assessment of baroreceptor reflex sensitivity (BRS) in the ovine fetus provides insight into autonomic cardiovascular regulation. Currently, assessment of BRS relies on vasoactive drugs, but this approach is limited by feasibility issues and by the nonphysiologic nature of the stimulus. Thus we aimed to validate the method of spontaneous BRS assessment against the reference method of using vasoactive drugs in preterm (0.76 gestation, n = 16) and near-term (0.86 gestation, n = 16) chronically instrumented ovine fetuses. The BRS measures derived from the spontaneous and reference methods correlated at both gestational ages (R = 0.67 ± 0.03). The sequence method of spontaneous BRS measures also correlated both to the root mean square of standard deviations (RMSSD), which is a measure of fetal heart rate variability reflecting vagal modulation (R = 0.69 ± 0.03), and to fetal body weight (R = 0.65 ± 0.03), which is a surrogate for growth trajectory of each fetus. The methodology presented may aid in developing new models to study BRS and cardiovascular control in ovine fetus in the last trimester of pregnancy.

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