Clinicopathologic Analysis of Inflammatory Myofibroblastic Tumors of the Urinary Bladder

2021 ◽  
Author(s):  
Patrick J. Hensley ◽  
Kelly K. Bree ◽  
Charles C. Guo ◽  
Niyati Lobo ◽  
Matthew T. Campbell ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Inflammatory Myofibroblastic Tumors

scholarly journals A Conservative Approach to Inflammatory Myofibroblastic Tumor of the Bladder: A Case Report and Review of Literature

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Rawad Abou Zahr ◽  
Elie Ghabi ◽  
Mehdi Idrissi-Kaitouni ◽  
Thierry Roumeguere
Keyword(s):  
Urinary Bladder ◽  
Conservative Therapy ◽  
Clinical Presentation ◽  
Benign Tumors ◽  
Conservative Approach ◽  
Review Of Literature ◽  
Gross Hematuria ◽  
Bladder Tumors ◽  
Inflammatory Myofibroblastic Tumors ◽  
Anatomic Locations

Inflammatory myofibroblastic tumors (IMTs) are particularly rare tumors that have been described in various anatomic locations, of which the urinary bladder is the most common. These benign tumors are amendable to conservative therapy but are notoriously difficult to diagnose given their mimicry of malignant sarcomas and sarcomatoid carcinomas, making an accurate diagnosis paramount to spare a patient radical and unnecessary treatment. We hereby present the case of a 37-year-old female patient who was diagnosed with an IMT of the urinary bladder during workup for painless gross hematuria. Patient was successfully managed with a laparoscopic partial cystectomy and is free of recurrence 5 years after surgery. IMTs are rare benign tumors that share the same clinical presentation as malignant bladder tumors. Deep biopsy and experienced pathologist are crucial in establishing diagnosis and avoiding patient radical treatment. This case is a classical demonstration of a remarkably rare tumor that was adequately managed with conservative therapy, achieving excellent clinical outcomes.

Inflammatory Myofibroblastic Tumors of the Urinary Bladder: A Systematic Review

Urology ◽  
2014 ◽  
Vol 84 (3) ◽  
pp. 503-508 ◽  
Author(s):  
Jeremy Yuen Chun Teoh ◽  
Ning-Hong Chan ◽  
Ho-Yuen Cheung ◽  
Simon See Ming Hou ◽  
Chi-Fai Ng
Keyword(s):  
Systematic Review ◽  
Urinary Bladder ◽  
Inflammatory Myofibroblastic Tumors

scholarly journals Transurethral Resection for the Treatment of an Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report

2019 ◽  
Vol 12 (2) ◽  
pp. 344-353
Author(s):  
Kamel Fadaak ◽  
Aali Al-Otaibi ◽  
Abdullah Al-Zahrani ◽  
Abdullah Alhaam ◽  
Omran Al-Dandan ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Transurethral Resection ◽  
Inflammatory Myofibroblastic Tumor ◽  
Bladder Tumor ◽  
Treatment Protocol ◽  
Complete Excision ◽  
Standardized Treatment ◽  
Inflammatory Myofibroblastic Tumors ◽  
Bladder Sparing

Inflammatory myofibroblastic tumors (IMT) of the urinary bladder is a remarkably rare bladder tumor. To this day, no standardized treatment protocol has been recognized. Here we report a case of bladder IMT in a 14-year-old girl presenting with urgency, frequency, and gross painless hematuria for a week. Complete excision of the bladder IMT was amenable with transurethral resection of bladder tumor (TURBT). Follow-up cystoscopy did not detect any recurrence. Minimally invasive bladder-sparing treatments are a valid option for treating IMT of the bladder.

Effect of verapamil on cytoplasmic distribution of granules and microfilaments in amphibian urinary bladder

1988 ◽  
Vol 46 ◽  
pp. 324-325
Author(s):  
A.J. Mia ◽  
L.X. Oakford ◽  
T. Yorio
Keyword(s):  
Urinary Bladder ◽  
Water Flow ◽  
Morphological Changes ◽  
Granular Cell ◽  
Cytosolic Calcium ◽  
Calcium Storage ◽  
Amphibian Urinary Bladder ◽  
Vesicular Membrane ◽  
High Concentrations ◽  
Cytoskeletal System

The amphibian urinary bladder has been used as a ‘model’ system for studies of the mechanism of action of antidiuretic hormone (ADH) in stimulating transepithelial water flow. The increase in water permeability is accompanied by morphological changes that include the stimulation of apical microvilli, mobilization of microtubules and microfilaments and vesicular membrane fusion events . It has been shown that alterations in the cytosolic calcium concentrations can inhibit ADH transmembrane water flow and induce alterations in the epithelial cell cytomorphology, including the cytoskeletal system . Recently, the subapical granules of the granular cell in the amphibian urinary bladder have been shown to contain high concentrations of calcium, and it was suggested that these cytoplasmic constituents may act as calcium storage sites for intracellular calcium homeostasis. The present study utilizes the calcium antagonist, verapamil, to examine the effect of calcium deprivation on the cytomorphological features of epithelial cells from amphibian urinary bladder, with particular emphasis on subapical granule and microfilament distribution.

Role of PKC isozymes in water transport in toad urinary bladder

1991 ◽  
Vol 49 ◽  
pp. 302-303
Author(s):  
A.J. Mia ◽  
L.X. Oakford ◽  
T. Yorio
Keyword(s):  
Urinary Bladder ◽  
Apical Membrane ◽  
Membrane Surface ◽  
Protein A ◽  
Cell Types ◽  
Leukemic Cells ◽  
Toad Urinary Bladder ◽  
Pkc Isozymes ◽  
Antibody Labeling

Protein kinase C (PKC) isozymes, when activated, are translocated to particulate membrane fractions for transport to the apical membrane surface in a variety of cell types. Evidence of PKC translocation was demonstrated in human megakaryoblastic leukemic cells, and in cardiac myocytes and fibroblasts, using FTTC immunofluorescent antibody labeling techniques. Recently, we reported immunogold localizations of PKC subtypes I and II in toad urinary bladder epithelia, following 60 min stimulation with Mezerein (MZ), a PKC activator, or antidiuretic hormone (ADH). Localization of isozyme subtypes I and n was carried out in separate grids using specific monoclonal antibodies with subsequent labeling with 20nm protein A-gold probes. Each PKC subtype was found to be distributed singularly and in discrete isolated patches in the cytosol as well as in the apical membrane domains. To determine if the PKC isozymes co-localized within the cell, a double immunogold labeling technique using single grids was utilized.

1199: Chronic Ischemia of the Urinary Bladder Causes Luts in Elderly Women and Men

2007 ◽  
Vol 177 (4S) ◽  
pp. 395-396
Author(s):  
Germar M. Pinggera ◽  
Leo Pallwein ◽  
Ferdinand Frauscher ◽  
Michael Mitterberger ◽  
Fritz Aigner ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Elderly Women ◽  
Chronic Ischemia

777: Tissue Microarray Analysis of pAkt, PTEN and L-Plastin in Urinary Bladder Cancer

2005 ◽  
Vol 173 (4S) ◽  
pp. 211-211
Author(s):  
Loleta D. Harris ◽  
Tomasz Tuziak ◽  
Jorge De Lo Cerda ◽  
Anita L. Sabichi ◽  
Ying Yang ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Urinary Bladder ◽  
Tissue Microarray ◽  
Microarray Analysis ◽  
Urinary Bladder Cancer ◽  
Tissue Microarray Analysis

1210: Reduced Activity of Afferent Neurons Innervating Urinary Bladder in Rats with Dibetic Cystopathy

2005 ◽  
Vol 173 (4S) ◽  
pp. 328-328
Author(s):  
Yukio Hayashi ◽  
Kazumasa Torimoto ◽  
Michael B. Chancellor ◽  
William C. de Groat ◽  
Naoki Yoshimura
Keyword(s):  
Urinary Bladder ◽  
Afferent Neurons ◽  
Reduced Activity
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