scholarly journals The role of prostaglandin and E series prostaglandin receptor type 4 receptors in the development of bladder overactivity in a rat model of chemically induced prostatic inflammation

2019 ◽  
Vol 124 (5) ◽  
pp. 883-891 ◽  
Author(s):  
Shinsuke Mizoguchi ◽  
Amanda S. Wolf-Johnson ◽  
Jianshu Ni ◽  
Kenichi Mori ◽  
Takahisa Suzuki ◽  
...  
Keyword(s):  
Rat Model ◽  
Receptor Type ◽  
Prostaglandin Receptor ◽  
Chemically Induced ◽  
Prostatic Inflammation

scholarly journals Effects of dutasteride in a rat model of chemically induced prostatic inflammation—Potential role of estrogen receptor β

The Prostate ◽  
2020 ◽  
Vol 80 (16) ◽  
pp. 1413-1420
Author(s):  
Shinsuke Mizoguchi ◽  
Kenichi Mori ◽  
Toshitaka Shin ◽  
Zhou Wang ◽  
Donald B. DeFranco ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Rat Model ◽  
Potential Role ◽  
Estrogen Receptor Β ◽  
Chemically Induced ◽  
Prostatic Inflammation

scholarly journals MP06-03 EFFECTS OF COX2 INHIBITION ON BLADDER OVERACTIVITY IN RAT MODEL OF CHEMICALLY INDUCED PROSTATIC INFLAMMATION

2019 ◽  
Vol 201 (Supplement 4) ◽  
Author(s):  
Shinsuke Mizoguchi* ◽  
Kenichi Mori ◽  
Hiromitsu Mimata ◽  
Jianshu Ni ◽  
Masahiro Kurobe ◽  
...  
Keyword(s):  
Rat Model ◽  
Chemically Induced ◽  
Prostatic Inflammation

Dissecting the role of Corticotropin-releasing hormone receptor type 1 in Alzheimer's Disease

2011 ◽  
Vol 44 (06) ◽  
Author(s):  
K Lerche ◽  
M Willem ◽  
K Kleinknecht ◽  
C Romberg ◽  
U Konietzko ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Hormone Receptor ◽  
Receptor Type ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone

Role of Natriuretic Peptide Receptor Type C in Dahl Salt-Sensitive Hypertensive Rats

Hypertension ◽  
1997 ◽  
Vol 30 (2) ◽  
pp. 177-183 ◽  
Author(s):  
Miki Nagase ◽  
Katsuyuki Ando ◽  
Takeshi Katafuchi ◽  
Akira Kato ◽  
Shigehisa Hirose ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Receptor Type ◽  
Natriuretic Peptide Receptor ◽  
Hypertensive Rats ◽  
Peptide Receptor ◽  
Type C

scholarly journals Longitudinal Expression of Testicular TAS1R3 from Prepuberty to Sexual Maturity in Congjiang Xiang Pigs

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 437
Author(s):  
Ting Gong ◽  
Weiyong Wang ◽  
Houqiang Xu ◽  
Yi Yang ◽  
Xiang Chen ◽  
...  
Keyword(s):  
Sexual Maturity ◽  
Cell Function ◽  
Expression Patterns ◽  
Taste Receptor ◽  
Receptor Type ◽  
Mrna Levels ◽  
Early Puberty ◽  
Specific Expression

Testicular expression of taste receptor type 1 subunit 3 (T1R3), a sweet/umami taste receptor, has been implicated in spermatogenesis and steroidogenesis in mice. We explored the role of testicular T1R3 in porcine postnatal development using the Congjiang Xiang pig, a rare Chinese miniature pig breed. Based on testicular weights, morphology, and testosterone levels, four key developmental stages were identified in the pig at postnatal days 15–180 (prepuberty: 30 day; early puberty: 60 day; late puberty: 90 day; sexual maturity: 120 day). During development, testicular T1R3 exhibited stage-dependent and cell-specific expression patterns. In particular, T1R3 levels increased significantly from prepuberty to puberty (p < 0.05), and expression remained high until sexual maturity (p < 0.05), similar to results for phospholipase Cβ2 (PLCβ2). The strong expressions of T1R3/PLCβ2 were observed at the cytoplasm of elongating/elongated spermatids and Leydig cells. In the eight-stage cycle of the seminiferous epithelium in pigs, T1R3/PLCβ2 levels were higher in the spermatogenic epithelium at stages II–VI than at the other stages, and the strong expressions were detected in elongating/elongated spermatids and residual bodies. The message RNA (mRNA) levels of taste receptor type 1 subunit 1 (T1R1) in the testis showed a similar trend to levels of T1R3. These data indicate a possible role of T1R3 in the regulation of spermatid differentiation and Leydig cell function.

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