Assessing the impact of renal artery clamping during laparoscopic partial nephrectomy (LPN) for small renal masses: the rationale and design of the CLamp vs Off Clamp Kidney during LPN (CLOCK II) randomised phase III trial

2019 ◽  
Vol 124 (3) ◽  
pp. 365-367
Author(s):  
Pierluigi Bove ◽  
Riccardo Bertolo ◽  
Marco Sandri ◽  
Giuseppe Farullo ◽  
Chiara Cipriani ◽  
...  
Keyword(s):  
Renal Artery ◽  
Partial Nephrectomy ◽  
Laparoscopic Partial Nephrectomy ◽  
Phase Iii ◽  
Small Renal Masses ◽  
Renal Masses ◽  
Phase Iii Trial ◽  
The Impact

The economic and clinical costs of chronic kidney disease following radical and partial nephrectomy in the management of small renal masses.

2011 ◽  
Vol 29 (7_suppl) ◽  
pp. 353-353
Author(s):  
S. L. Chang ◽  
L. E. Cipriano ◽  
L. C. Harshman ◽  
B. I. Chung
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Health Outcomes ◽  
Partial Nephrectomy ◽  
Base Case ◽  
Small Renal Masses ◽  
Renal Masses ◽  
Lifetime Horizon ◽  
Life Years ◽  
The Impact

353 Background: Postoperative chronic kidney disease (PCKD), defined as a glomerular filtration rate of < 60mL/min/1.73m2, is a recognized adverse outcome after extirpative therapy for small renal masses (SRM, ≤ 4cm). We quantified the long-term economic and clinical costs of PCKD following radical and partial nephrectomy for the management of SRM. Methods: Using a Markov model, we evaluated open and laparoscopic approaches for radical and partial nephrectomy in the treatment of SRMs. The base case was a 65-year old healthy individual with a unilateral SRM and normal renal function. We used a 3-month cycle length, lifetime horizon, societal perspective, and 3% discount rate. The costs, quality of life adjustments, and transition probabilities were estimated from the literature, Medicare, and expert opinion. Health outcomes were measured in quality-adjusted life-years (QALY) gained and costs in 2008 U.S. dollars. The model was tested with sensitivity analyses. Results: The average discounted lifetime outcomes are listed in the Table. There were minimal differences between the open and laparoscopic approaches. PCKD led to a substantial increase costs and decrease in health outcomes. The impact of PCKD was indirectly associated with age. Conclusions: Partial nephrectomy provides cost-savings and improved health outcomes compared to radical nephrectomy in the management of patients with SRMs. Both procedures incur significant economic and clinical costs due to the development of PCKD. A discussion about the potential for PCKD should be incorporated into the informed consent for surgical treatment of SRMs. [Table: see text] No significant financial relationships to disclose.

Decision Tree for Laparoscopic Partial Nephrectomy Versus Laparoscopic Renal Cryoablation for Small Renal Masses

2009 ◽  
Vol 23 (3) ◽  
pp. 431-437 ◽  
Author(s):  
Alan A. Nisbet ◽  
Jocelyn M. Rieder ◽  
Viet Q. Tran ◽  
Stephen G. Williams ◽  
Gary W. Chien
Keyword(s):  
Decision Tree ◽  
Partial Nephrectomy ◽  
Laparoscopic Partial Nephrectomy ◽  
Small Renal Masses ◽  
Renal Masses

scholarly journals 80: Laparoscopic Cryoablation vs. Laparoscopic Partial Nephrectomy for Small Renal Masses: A Matched Cohort Study

2006 ◽  
Vol 175 (4S) ◽  
pp. 26-27
Author(s):  
Rebecca L. O'Malley ◽  
Aaron D. Berger ◽  
Jamie A. Kanofsky ◽  
Courtney K. Phillips ◽  
Michael D. Stifelman ◽  
...  
Keyword(s):  
Cohort Study ◽  
Partial Nephrectomy ◽  
Laparoscopic Partial Nephrectomy ◽  
Matched Cohort ◽  
Small Renal Masses ◽  
Renal Masses ◽  
Matched Cohort Study
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