How can we expand active surveillance criteria in patients with low- and intermediate-risk prostate cancer without increasing the risk of misclassification? Development of a novel risk calculator

2018 ◽  
Vol 122 (5) ◽  
pp. 823-830 ◽  
Author(s):  
Giorgio Gandaglia ◽  
Roderick C.N. van den Bergh ◽  
Derya Tilki ◽  
Nicola Fossati ◽  
Piet Ost ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Active Surveillance ◽  
Intermediate Risk ◽  
Risk Calculator ◽  
Risk Prostate Cancer ◽  
Risk Of Misclassification

Active surveillance for intermediate‐risk prostate cancer in African American and non‐Hispanic White men

Cancer ◽  
2021 ◽  
Author(s):  
P. Travis Courtney ◽  
Rishi Deka ◽  
Nikhil V. Kotha ◽  
Daniel R. Cherry ◽  
Mia A. Salans ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
Active Surveillance ◽  
White Men ◽  
Intermediate Risk ◽  
Risk Prostate Cancer ◽  
Hispanic White

Adverse Disease Features in Gleason Score 3 + 4 “Favorable Intermediate-Risk” Prostate Cancer: Implications for Active Surveillance

2017 ◽  
Vol 72 (3) ◽  
pp. 442-447 ◽  
Author(s):  
Alessandro Morlacco ◽  
John C. Cheville ◽  
Laureano J. Rangel ◽  
Derek J. Gearman ◽  
R. Jeffrey Karnes
Keyword(s):  
Prostate Cancer ◽  
Active Surveillance ◽  
Gleason Score ◽  
Intermediate Risk ◽  
Risk Prostate Cancer

Outcomes of Active Surveillance for Men with Intermediate Risk Prostate Cancer, A Population-Based Analysis

Urology ◽  
2021 ◽  
Author(s):  
Thenappan Chandrasekar ◽  
Nicholas Bowler ◽  
Adam Schneider ◽  
Hanan Goldberg ◽  
James R. Mark ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Active Surveillance ◽  
Population Based ◽  
Intermediate Risk ◽  
Risk Prostate Cancer

scholarly journals Prostate Cancer Grade and Stage Misclassification in Active Surveillance Candidates: Black Versus White Patients

2020 ◽  
Vol 18 (11) ◽  
pp. 1492-1499
Author(s):  
Lara Franziska Stolzenbach ◽  
Giuseppe Rosiello ◽  
Angela Pecoraro ◽  
Carlotta Palumbo ◽  
Stefano Luzzago ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Active Surveillance ◽  
Temporal Trend ◽  
Low Risk ◽  
Intermediate Risk ◽  
Multivariate Logistic Regression ◽  
Black Patients ◽  
Risk Prostate Cancer ◽  
Misclassification Rates ◽  
White Patients

Background: Misclassification rates defined as upgrading, upstaging, and upgrading and/or upstaging have not been tested in contemporary Black patients relative to White patients who fulfilled criteria for very-low-risk, low-risk, or favorable intermediate-risk prostate cancer. This study aimed to address this void. Methods: Within the SEER database (2010–2015), we focused on patients with very low, low, and favorable intermediate risk for prostate cancer who underwent radical prostatectomy and had available stage and grade information. Descriptive analyses, temporal trend analyses, and multivariate logistic regression analyses were used. Results: Overall, 4,704 patients with very low risk (701 Black vs 4,003 White), 17,785 with low risk (2,696 Black vs 15,089 White), and 11,040 with favorable intermediate risk (1,693 Black vs 9,347 White) were identified. Rates of upgrading and/or upstaging in Black versus White patients were respectively 42.1% versus 37.7% (absolute Δ = +4.4%; P<.001) in those with very low risk, 48.6% versus 46.0% (absolute Δ = +2.6%; P<.001) in those with low risk, and 33.8% versus 35.3% (absolute Δ = –1.5%; P=.05) in those with favorable intermediate risk. Conclusions: Rates of misclassification were particularly elevated in patients with very low risk and low risk, regardless of race, and ranged from 33.8% to 48.6%. Recalibration of very-low-, low-, and, to a lesser extent, favorable intermediate-risk active surveillance criteria may be required. Finally, our data indicate that Black patients may be given the same consideration as White patients when active surveillance is an option. However, further validations should ideally follow.

Pathologic Outcomes of Gleason 6 Favorable Intermediate-Risk Prostate Cancer Treated With Radical Prostatectomy: Implications for Active Surveillance

2018 ◽  
Vol 16 (3) ◽  
pp. 226-234 ◽  
Author(s):  
David D. Yang ◽  
Brandon A. Mahal ◽  
Vinayak Muralidhar ◽  
Marie E. Vastola ◽  
Ninjin Boldbaatar ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Active Surveillance ◽  
Intermediate Risk ◽  
Risk Prostate Cancer

Active surveillance for intermediate-risk prostate cancer

2019 ◽  
Vol 29 (6) ◽  
pp. 605-611
Author(s):  
Maya R. Overland ◽  
Samuel L. Washington ◽  
Peter R. Carroll ◽  
Matthew R. Cooperberg ◽  
Annika Herlemann
Keyword(s):  
Prostate Cancer ◽  
Active Surveillance ◽  
Intermediate Risk ◽  
Risk Prostate Cancer
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