Does cumulative prostate cancer length (CCL) in prostate biopsies improve prediction of clinically insignificant cancer at radical prostatectomy in patients eligible for active surveillance?

2014 ◽  
Vol 116 (2) ◽  
pp. 220-229 ◽  
Author(s):  
Derrick J. Chen ◽  
Sara M. Falzarano ◽  
Jesse K. McKenney ◽  
Chris G. Przybycin ◽  
Jordan P. Reynolds ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Active Surveillance ◽  
Prostate Biopsies ◽  
Insignificant Cancer

scholarly journals Assessment of PSIM (Prostatic Systemic Inflammatory Markers) Score in Predicting Pathologic Features at Robotic Radical Prostatectomy in Patients with Low-Risk Prostate Cancer Who Met the Inclusion Criteria for Active Surveillance

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 355
Author(s):  
Matteo Ferro ◽  
Gennaro Musi ◽  
Deliu Victor Matei ◽  
Alessandro Francesco Mistretta ◽  
Stefano Luzzago ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Active Surveillance ◽  
Inflammatory Markers ◽  
Low Risk ◽  
Inclusion Criteria ◽  
Robotic Radical Prostatectomy ◽  
Lymphocyte Ratio ◽  
Risk Prostate Cancer ◽  
Low Risk Prostate Cancer

Background: circulating levels of lymphocytes, platelets and neutrophils have been identified as factors related to unfavorable clinical outcome for many solid tumors. The aim of this cohort study is to evaluate and validate the use of the Prostatic Systemic Inflammatory Markers (PSIM) score in predicting and improving the detection of clinically significant prostate cancer (csPCa) in men undergoing robotic radical prostatectomy for low-risk prostate cancer who met the inclusion criteria for active surveillance. Methods: we reviewed the medical records of 260 patients who fulfilled the inclusion criteria for active surveillance. We performed a head-to-head comparison between the histological findings of specimens after radical prostatectomy (RP) and prostate biopsies. The PSIM score was calculated on the basis of positivity according to cutoffs (neutrophil-to-lymphocyte ratio (NLR) 2.0, platelets-to-lymphocyte ratio (PLR) 118 and monocyte-to-lymphocyte-ratio (MLR) 5.0), with 1 point assigned for each value exceeding the specified threshold and then summed, yielding a final score ranging from 0 to 3. Results: median NLR was 2.07, median PLR was 114.83, median MLR was 3.69. Conclusion: we found a significantly increase in the rate of pathological International Society of Urological Pathology (ISUP) ≥ 2 with the increase of PSIM. At the multivariate logistic regression analysis adjusted for age, prostate specific antigen (PSA), PSA density, prostate volume and PSIM, the latter was found the sole independent prognostic variable influencing probability of adverse pathology.

1387 EFFECT OF REPEATED PROSTATE BIOPSIES ON ERECTILE FUNCTION IN MEN UNDER ACTIVE SURVEILLANCE FOR PROSTATE CANCER

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Katharina Braun ◽  
Youness Ahallal ◽  
Tarek P. Ghoneim ◽  
Mario Esteban ◽  
Daniel Sjoberg ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Active Surveillance ◽  
Erectile Function ◽  
Prostate Biopsies

MP43-18 FOR MEN ON ACTIVE SURVEILLANCE FOR PROSTATE CANCER, OLDER AGE AT DIAGNOSIS AND AT RADICAL PROSTATECTOMY PORTENDS POOR OUTCOMES

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Sasha Druskin ◽  
Mufaddal Mamawala ◽  
Jeffrey Tosoian ◽  
H. Ballentine Carter ◽  
Bruce Trock
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Active Surveillance ◽  
Older Age ◽  
Age At Diagnosis ◽  
Poor Outcomes

A comprehensive analysis of cost of an active surveillance cohort compared to radical prostatectomy as primary treatment for prostate cancer

2018 ◽  
Vol 37 (7) ◽  
pp. 1297-1303 ◽  
Author(s):  
Carmen Pozo ◽  
Virginia Hernández ◽  
Carlos Capitán ◽  
Enrique de la Peña ◽  
Guillermo Fernández-Conejo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Active Surveillance ◽  
Primary Treatment ◽  
Comprehensive Analysis
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