What drives transcranial Doppler velocity improvement in paediatric sickle cell anaemia: analysis from the Sickle Cell Clinical Research and Intervention Program (SCCRIP) longitudinal cohort study

2021 ◽  
Author(s):  
Jeremie H. Estepp ◽  
Ze Cong ◽  
Irene Agodoa ◽  
Guolian Kang ◽  
Juan Ding ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clinical Research ◽  
Sickle Cell ◽  
Transcranial Doppler ◽  
Intervention Program ◽  
Sickle Cell Anaemia ◽  
Longitudinal Cohort Study ◽  
Doppler Velocity ◽  
Longitudinal Cohort

scholarly journals Transcranial Doppler velocity among Jamaican children with sickle cell anaemia: determining the significance of haematological values and nutrition

2018 ◽  
Vol 181 (2) ◽  
pp. 242-251 ◽  
Author(s):  
Angela E. Rankine-Mullings ◽  
Nadine Morrison-Levy ◽  
Deanne Soares ◽  
Karen Aldred ◽  
Lesley King ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Transcranial Doppler ◽  
Sickle Cell Anaemia ◽  
Doppler Velocity ◽  
Haematological Values

scholarly journals Organ damage in sickle cell disease study (ORDISS): protocol for a longitudinal cohort study based in Ghana

BMJ Open ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. e016727 ◽  
Author(s):  
Kofi A Anie ◽  
Vivian Paintsil ◽  
Ellis Owusu-Dabo ◽  
Daniel Ansong ◽  
Alex Osei-Akoto ◽  
...  
Keyword(s):  
Cohort Study ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Clinical History ◽  
Organ Damage ◽  
Longitudinal Cohort Study ◽  
Cell Disease ◽  
Longitudinal Cohort ◽  
Public Health Burden ◽  
Disease Study

IntroductionSickle cell disease is highly prevalent in Africa with a significant public health burden. Nonetheless, morbidity and mortality in sickle cell disease that result from the progression of organ damage is not well understood. The Organ Damage in Sickle Cell Disease Study (ORDISS) is designed as a longitudinal cohort study to provide critical insight into cellular and molecular pathogenesis of chronic organ damage for the development of future innovative treatment.Methods and analysisORDISS aims to recruit children aged 0–15 years who attend the Kumasi Centre for Sickle Cell Disease based at the Komfo Anokye Teaching Hospital in Kumasi, Ghana. Consent is obtained to collect blood and urine samples from the children during specified clinic visits and hospitalisations for acute events, to identify candidate and genetic markers of specific organ dysfunction and end-organ damage, over a 3 year period. In addition, data concerning clinical history and complications associated with sickle cell disease are collected. Samples are stored in biorepositories and analysed at the Kumasi Centre for Collaborative Research in Tropical Medicine, Ghana and the Centre for Translational and International Haematology, University of Pittsburgh, USA. Appropriate statistical analyses will be performed on the data acquired.Ethics and disseminationResearch ethics approval was obtained at all participating sites. Results of the study will be submitted for publication in peer-reviewed journals, and the key findings presented at national and international conferences.

scholarly journals Prognostic factors of disease severity in infants with sickle cell anemia: A comprehensive longitudinal cohort study

2018 ◽  
Vol 93 (11) ◽  
pp. 1411-1419 ◽  
Author(s):  
Valentine Brousse ◽  
Sara El Hoss ◽  
Naïm Bouazza ◽  
Cécile Arnaud ◽  
Francoise Bernaudin ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prognostic Factors ◽  
Disease Severity ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort

Sickle Cell Clinical Research and Intervention Program (SCCRIP): A lifespan cohort study for sickle cell disease progression from the pediatric stage into adulthood

2018 ◽  
Vol 65 (9) ◽  
pp. e27228 ◽  
Author(s):  
Jane S. Hankins ◽  
Jeremie H. Estepp ◽  
Jason R. Hodges ◽  
Martha A. Villavicencio ◽  
Leslie L. Robison ◽  
...  
Keyword(s):  
Cohort Study ◽  
Sickle Cell Disease ◽  
Clinical Research ◽  
Disease Progression ◽  
Sickle Cell ◽  
Intervention Program ◽  
Cell Disease

2453-PUB: Changes in Metabolic Syndrome and Diabetes Risk: A Nationwide Longitudinal Cohort Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 2453-PUB
Author(s):  
MIN-KYUNG LEE ◽  
HYUK-SANG KWON ◽  
KI-HO SONG ◽  
JAE HYUK LEE
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Diabetes Risk ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort
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