Combined haploidentical and cord blood transplantation for refractory severe aplastic anaemia and hypoplastic myelodysplastic syndrome

2021 ◽  
Author(s):  
Richard W. Childs ◽  
Xin Tian ◽  
Phuong Vo ◽  
Enkhtsetseg Purev ◽  
Ritesh R. Kotecha ◽  
...  
Keyword(s):  
Myelodysplastic Syndrome ◽  
Cord Blood ◽  
Aplastic Anaemia ◽  
Cord Blood Transplantation ◽  
Severe Aplastic Anaemia ◽  
Blood Transplantation

Successful cord blood transplantation for myelodysplastic syndrome complicated by Mycobacterium kansasii pneumonia

2020 ◽  
Author(s):  
Arisa Yamada ◽  
Daigo Akahane ◽  
Seiichiro Katagiri ◽  
Seiichiro Yoshizawa ◽  
Nahoko Furuya ◽  
...  
Keyword(s):  
Myelodysplastic Syndrome ◽  
Cord Blood ◽  
Cord Blood Transplantation ◽  
Mycobacterium Kansasii ◽  
Blood Transplantation

Unrelated cord blood transplantation for adult patients with advanced myelodysplastic syndrome

Blood ◽  
2003 ◽  
Vol 101 (12) ◽  
pp. 4711-4713 ◽  
Author(s):  
Jun Ooi ◽  
Tohru Iseki ◽  
Satoshi Takahashi ◽  
Akira Tomonari ◽  
Koji Ishii ◽  
...  
Keyword(s):  
Myelodysplastic Syndrome ◽  
Cord Blood ◽  
Median Time ◽  
Cord Blood Transplantation ◽  
Chronic Gvhd ◽  
Disease Free Survival ◽  
Adult Patients ◽  
Unrelated Cord Blood Transplantation ◽  
Blood Transplantation ◽  
Unrelated Cord Blood

AbstractWe report the results of unrelated cord blood transplantation (CBT) for 13 adult patients with advanced myelodysplastic syndrome (MDS). The median age was 40 years, the median weight was 51 kg, and the median number of infused nucleated cells was 2.43 × 107/kg. Twelve patients had myeloid reconstitution, and the median time to more than 0.5 × 109/L (5 × 108/L) absolute neutrophil count was 22.5 days. A self-sustained platelet count more than 50 × 109/L was achieved in 11 patients at a median time of 49 days. Acute graft versus host disease (GVHD) occurred in 9 of 12 evaluable patients and chronic GVHD in 8 of 11 evaluable patients. Ten patients are alive and free of disease at between 171 and 1558 days after transplantation. The probability of disease-free survival at 2 years was 76.2%. These results suggest that adult advanced MDS patients without suitable related or unrelated bone marrow donors should be considered as candidates for CBT.

Successful cord blood transplantation in a girl with monosomy 7 myelodysplastic syndrome and reduced numbers of B cells

2010 ◽  
Vol 91 (4) ◽  
pp. 705-707
Author(s):  
Chien-Chung Lee ◽  
Chao-Ping Yang ◽  
Ming Horng Tsai ◽  
Wen-I Lee ◽  
En-Chen Fang ◽  
...  
Keyword(s):  
B Cells ◽  
Myelodysplastic Syndrome ◽  
Cord Blood ◽  
Cord Blood Transplantation ◽  
Monosomy 7 ◽  
Blood Transplantation
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