scholarly journals Combination of a mitogen‐activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion‐based residual disease and prevents re‐expansion of FLT3 ‐ITD acute myeloid leukaemia

2020 ◽  
Vol 191 (2) ◽  
pp. 231-242
Author(s):  
Joanna Zabkiewicz ◽  
Michelle Lazenby ◽  
Gareth Edwards ◽  
Ceri A. Bygrave ◽  
Nader Omidvar ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Protein Kinase ◽  
Acute Myeloid Leukaemia ◽  
Tyrosine Kinase Inhibitor ◽  
Myeloid Leukaemia ◽  
Kinase Inhibitor ◽  
Residual Disease ◽  
Mitogen Activated Protein Kinase ◽  
Mitogen Activated Protein ◽  
Acute Myeloid

Tyrosine kinase inhibitor insensitivity of non-cycling CD34+ human acute myeloid leukaemia cells with FMS-like tyrosine kinase 3 mutations

2011 ◽  
Vol 154 (4) ◽  
pp. 457-465 ◽  
Author(s):  
Caroline L. Alvares ◽  
Tino Schenk ◽  
Sanna Hulkki ◽  
Toon Min ◽  
Gowri Vijayaraghavan ◽  
...  
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Myeloid Leukaemia ◽  
Kinase Inhibitor ◽  
Acute Myeloid
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