scholarly journals Autoimmune diseases, infections, use of antibiotics and the risk of acute myeloid leukaemia: a national population-based case-control study

2018 ◽  
Vol 181 (2) ◽  
pp. 205-214 ◽  
Author(s):  
Lene S. G. Østgård ◽  
Mette Nørgaard ◽  
Lars Pedersen ◽  
René D. Østgård ◽  
Bruno C. Medeiros ◽  
...  
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Autoimmune Diseases ◽  
Myeloid Leukaemia ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
National Population ◽  
Control Study ◽  
Acute Myeloid

scholarly journals NSAID consumption and risk of acute myeloid leukemia: a national population-based case-control study

2018 ◽  
Vol Volume 10 ◽  
pp. 5043-5051 ◽  
Author(s):  
Lene Østgård ◽  
Mette Nørgaard ◽  
Lars Pedersen ◽  
René Østgård ◽  
Lone Friis ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
National Population ◽  
Nsaid Consumption ◽  
Control Study ◽  
Acute Myeloid

scholarly journals Chronic rhinosinusitis and premorbid autoimmune diseases: a population-based case–control study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Liang-Chun Shih ◽  
Hua-Hsin Hsieh ◽  
Gregory J. Tsay ◽  
Ivan T. Lee ◽  
Yung-An Tsou ◽  
...  
Keyword(s):  
Autoimmune Diseases ◽  
Chronic Rhinosinusitis ◽  
Large Scale ◽  
Case Control Study ◽  
Comparison Group ◽  
Fungal Infections ◽  
Population Based ◽  
Case Control ◽  
Research Database ◽  
Control Study

Abstract Evidence shows that chronic rhinosinusitis (CRS) is associated with prior presence of autoimmune diseases; however, large-scale population-based studies in the literature are limited. We conducted a population-based case–control study investigating the association between CRS and premorbid autoimmune diseases by using the National Health Insurance Research Database in Taiwan. The CRS group included adult patients newly diagnosed with CRS between 2001 and 2013. The date of diagnosis was defined as the index date. The comparison group included individuals without CRS, with 1:4 frequency matching for gender, age, and index year. Premorbid diseases were forward traced to 1996. Univariate and multivariate logistic regression was performed to estimate odds ratios (ORs) and 95% confidence intervals. The CRS group consisted of 30,611 patients, and the comparison group consisted of 122,444 individuals. Patients with CRS had a higher significant association with premorbid autoimmune diseases (adjusted OR 1.39 [1.28–1.50]). Specifically, patients with CRS had a higher significant association with ankylosing spondylitis, polymyositis, psoriasis, rheumatoid arthritis, sicca syndrome, and systemic lupus erythematosus (adjusted OR 1.49 [1.34–1.67], 3.47 [1.12–10.8], 1.22 [1.04–1.43], 1.60 [1.31–1.96], 2.10 [1.63–2.72], and 1.69 [1.26–2.25]). In subgroup analysis, CRS with and without nasal polyps demonstrated a significant association with premorbid autoimmune diseases (adjusted OR 1.34 [1.14–1.58] and 1.50 [1.38–1.62]). In addition, CRS with fungal and non-fungal infections also demonstrated a significant association with premorbid autoimmune diseases (adjusted OR 2.02 [1.72–2.49] and 1.39 [1.28–1.51]). In conclusion, a significant association between CRS and premorbid autoimmune diseases has been identified. These underlying mechanisms need further investigation.

Breastfeeding is associated with lower risk for multiple sclerosis

2012 ◽  
Vol 19 (5) ◽  
pp. 553-558 ◽  
Author(s):  
Silja Conradi ◽  
Uwe Malzahn ◽  
Friedemann Paul ◽  
Sabine Quill ◽  
Lutz Harms ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Autoimmune Diseases ◽  
Lower Risk ◽  
Case Control Study ◽  
Multivariable Analysis ◽  
Population Based ◽  
Case Control ◽  
Multivariable Logistic Regression Analysis ◽  
Protective Effects ◽  
Control Study

Background:Multiple sclerosis (MS) is an autoimmune disease with known genetic and environmental susceptibility factors. Breastfeeding has been shown to be protective in other autoimmune diseases.Objective:This case-control study analyzed the association of breastfeeding in infancy on the risk of developing MS.Methods:A case-control study was performed in Berlin of 245 MS patients and 296 population-based controls, who completed a standardized questionnaire on their history and duration of breastfeeding in infancy and demographic characteristics. Univariable and multivariable logistic regression analysis was performed to investigate the association between breastfeeding and MS. The multivariate model was adjusted for age, gender, number of older siblings, number of inhabitants in place of domicile between ages 0 and 6 (categorized in each case), and daycare attendance between ages 0 and 3.Results:In multivariable analysis, breastfeeding showed an independent association with MS (adjusted OR 0.58; p = 0.028). However, with no breastfeeding as reference, the protective effect only emerges after four months of breastfeeding (multivariable analysis for ≤ four months adjusted OR 0.87; p = 0.614 and for > four months OR 0.51; p = 0.016).Conclusion:The results of this case-control study support the hypothesis that breastfeeding is associated with a lower risk of MS. These results are in line with findings of previous studies on other autoimmune diseases, in which breastfeeding was shown to have protective effects.

scholarly journals Occupational exposure to solvents and acute myeloid leukemia: a population-based, case–control study in four Nordic countries

2014 ◽  
Vol 40 (5) ◽  
pp. 511-517 ◽  
Author(s):  
Madar Talibov ◽  
Susanna Lehtinen-Jacks ◽  
Jan Ivar Martinsen ◽  
Kristina Kjærheim ◽  
Elsebeth Lynge ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Occupational Exposure ◽  
Myeloid Leukemia ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Nordic Countries ◽  
Control Study ◽  
Acute Myeloid

scholarly journals Passive smoking and stroke in men and women: a national population-based case-control study in China

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Lei Hou ◽  
Wei Han ◽  
Jingmei Jiang ◽  
Boqi Liu ◽  
Yanping Wu ◽  
...  
Keyword(s):  
Passive Smoking ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Men And Women ◽  
National Population ◽  
Control Study
Sign in / Sign up

Export Citation Format

Share Document