scholarly journals Nelarabine-induced peripheral and central neurotoxicity: can sequential MRI brain imaging help to define its natural history?

2017 ◽  
Vol 179 (2) ◽  
pp. 294-297 ◽  
Author(s):  
Karl Ewins ◽  
Andrea Malone ◽  
Ethna Phelan ◽  
David Webb ◽  
J. C. McHugh ◽  
...  
Keyword(s):  
Natural History ◽  
Brain Imaging ◽  
Mri Brain ◽  
Central Neurotoxicity

scholarly journals CNS imaging studies in cystic fibrosis patients presenting with sudden neurological events

2019 ◽  
Vol 6 (1) ◽  
pp. e000456
Author(s):  
Samantha Ellis ◽  
Catherine Rang ◽  
Tom Kotsimbos ◽  
Dominic Keating ◽  
Felicity Finlayson ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Brain Imaging ◽  
Medical Records ◽  
Seizure Activity ◽  
Neurological Complications ◽  
Neurological Symptoms ◽  
Imaging Studies ◽  
Vascular Events ◽  
Mri Brain ◽  
Large Teaching Hospital

BackgroundAcute neurological events may present as an extrapulmonary complication in patients with cystic fibrosis (CF). These events can be secondary to a range of different aetiologies.MethodsA retrospective analysis of 476 medical records of CF patients attending a large teaching hospital between 2000 and 2018 was performed. Patients presenting with acute neurological events who had MRI brain imaging were evaluated. Patients who had headaches without associated neurological symptoms were excluded from this analysis.ResultsAcute neurological presentations, excluding headaches without associated neurological symptoms, were reported in 27 index patients out of the 476 patients. Of these, 16 patients had MRI brain imaging for review. Three patients suffered pathology secondary to vascular events, both ischaemic and haemorrhagic; four patients had evidence of ischaemia or infarction not consistent with a vascular territory stroke and the remaining patients experienced a range of different neurological events. The most common presentation among these patients was seizure activity, followed by a transient motor or sensory deficit.ConclusionsNeurological complications are recognised among individuals with CF. Although rare, they can be secondary to a range of different aetiologies, including dysfunctional cell energetics. Additional studies are required to further evaluate this association.

scholarly journals MRI Brain Imaging in Assessment of Pediatric Head Trauma

2018 ◽  
Vol 3 (1) ◽  
pp. 19-26
Author(s):  
Kathan Amin ◽  
◽  
Sharjeel Israr ◽  
Dheeraj Reddy Gopireddy ◽  
Unni Udayasankar ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Head Trauma ◽  
Mri Brain ◽  
Pediatric Head Trauma

A giant cause of stroke

2014 ◽  
Vol 13 (2) ◽  
pp. 68-71
Author(s):  
Kelvin Ka Yin Kong ◽  
◽  
Andrew D Mackinnon ◽  
Leslie R Bridges ◽  
Geoffrey C Cloud ◽  
...  
Keyword(s):  
Giant Cell Arteritis ◽  
Brain Imaging ◽  
Giant Cell ◽  
Granulomatous Inflammation ◽  
Temporal Artery ◽  
Posterior Circulation ◽  
Vascular Imaging ◽  
Temporal Artery Biopsy ◽  
Mri Brain ◽  
Vertebral Arteries

An 80 year old man presented subacutely with drowsiness and confusion. Subsequent MRI brain imaging demonstrated multiple posterior circulation infarcts. Extracranial vasculitis was suspected when his ESR was found to be high and vascular imaging showed multifocal irregular narrowing of both vertebral arteries. This was confirmed by targeted temporal artery biopsy, which showed chronic granulomatous inflammation typical of giant cell arteritis (GCA). The patient made a significant recovery following treatment with prednisolone.

scholarly journals 170. Study of 3D scan using fast spin echo on 0.5T MRI : Brain imaging

1994 ◽  
Vol 50 (8) ◽  
pp. 1088
Author(s):  
Hiroshi Yasue ◽  
Kazuhiro Kawabata ◽  
Yoshihiro Sakaguchi ◽  
Hiroyoshi Fujioka ◽  
Junko Habe ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Spin Echo ◽  
Fast Spin Echo ◽  
Mri Brain ◽  
3D Scan ◽  
Fast Spin

Intracranial Arteriovenous Malformations

2019 ◽  
pp. 585-593
Author(s):  
Kelly D. Flemming ◽  
Michael J. Link
Keyword(s):  
Natural History ◽  
Brain Imaging ◽  
Intracranial Hemorrhage ◽  
Vascular Malformation ◽  
Arteriovenous Malformations ◽  
Medical Attention ◽  
Intracranial Arteriovenous Malformations ◽  
Radiographic Findings ◽  
Intracranial Vascular Malformation ◽  
Arteries And Veins

Intracranial arteriovenous malformations (AVMs) are a type of intracranial vascular malformation that consists of an abnormal connection of arteries and veins without intervening capillary beds. AVMs may come to medical attention because of seizure, intracranial hemorrhage, or incidental radiographic findings in a patient undergoing brain imaging for a different indication. This chapter focuses on the epidemiology, natural history, diagnosis, and management of intracranial AVMs.

scholarly journals MRI Evaluation of Patients with Empty Sella - A Retrospective Study K.S. Hegde Medical Academy, Mangalore

2021 ◽  
Vol 10 (34) ◽  
pp. 2879-2883
Author(s):  
Mourish Asokan ◽  
Rohini Avantsa ◽  
Alan Anchan
Keyword(s):  
Retrospective Study ◽  
Intracranial Hypertension ◽  
Brain Imaging ◽  
Incidental Finding ◽  
Sella Turcica ◽  
Empty Sella ◽  
Mri Brain ◽  
Mri Features ◽  
Medical Academy ◽  
Centre Hospital

BACKGROUND Empty Sella is often an incidental finding in brain imaging studies. However, in the recent past, its association with hormonal and intracranial hypertension has been researched by various authors. The main purpose of the present study was to evaluate the MRI features of patients with empty sella presented for routine MRI brain imaging. METHODS This is a single-centre, hospital-based, observational, and retrospective study. MRI brain of 67 patients with empty sella was retrospectively reviewed from January 2012 to October 2020. All patients had been referred to the Department of Radiodiagnosis with clinical suspicion of intracranial pathology. The various manifestations and their complications were evaluated. RESULTS This present study comprised 39 males (58 %) and 28 females (42 %). The most common age group was 41 - 60 years with a mean age of 49 years. The most common presenting symptom was headache (34 %). In MRI brain study, 93 % of the cases of empty sella was an incidental finding. In 24 % of the patients, empty sella was associated with MRI features of intracranial hypertension and 13 % with idiopathic intracranial hypertension. 62.5 % of the patients with intracranial hypertension had complete empty sella compared to 82 % of the patients with no features of intracranial hypertension and had partial empty sella even though the association was not statistically significant. CONCLUSIONS The significance of the MRI finding of an empty sella turcica can be determined using a combination of clinical and imaging findings. KEY WORDS Empty Sella, MRI, Intracranial Hypertension.

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