scholarly journals Investigation and treatment for iron deficiency in heart failure: the unmet need in Lower and Middle Income Countries

2017 ◽  
Vol 177 (6) ◽  
pp. 896-904 ◽  
Author(s):  
Abel Makubi ◽  
David J. Roberts
Keyword(s):  
Heart Failure ◽  
Iron Deficiency ◽  
Unmet Need ◽  
Middle Income ◽  
Middle Income Countries

A REVIEW ON GLOBAL TRENDS IN HEART FAILURE AND EVOLUTION OF ANGIOTENSIN–NEPRILYSIN INHIBITOR

2020 ◽  
pp. 32-37
Author(s):  
VEERENDRA UPPARA ◽  
SAISEKHAR KODIVANDLA ◽  
ASHIK ALI SHAIK
Keyword(s):  
Heart Failure ◽  
Public Health Problem ◽  
Global Public Health ◽  
Middle Income ◽  
Global Trends ◽  
Middle Income Countries ◽  
Health Loss ◽  
Neprilysin Inhibitor ◽  
Health Related ◽  
Global Public Health Problem

Heart failure (HF) is a major global public health problem irrespective of its causes. It generates an enormous clinical, societal, and economic, health loss burden with an increase in its prevalence reaching an epidemic proportion. The morbidity and mortality associated with heart failure are increasing the health-related burdens worldwide, especially in low- and middle-income countries. This review highlights the trends in HF burden, the clinical spectrum of HF, and the importance of neurohormonal pathways and the evolution of angiotensin receptor neprilysin inhibition in HF with updated clinical practice guidelines.

scholarly journals Heart Failure Care in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

PLoS Medicine ◽  
2014 ◽  
Vol 11 (8) ◽  
pp. e1001699 ◽  
Author(s):  
Thomas Callender ◽  
Mark Woodward ◽  
Gregory Roth ◽  
Farshad Farzadfar ◽  
Jean-Christophe Lemarie ◽  
...  
Keyword(s):  
Heart Failure ◽  
Systematic Review ◽  
Meta Analysis ◽  
Middle Income ◽  
Heart Failure Care ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Human Immunodeficiency Virus and Heart Failure in Low- and Middle-Income Countries

2015 ◽  
Vol 3 (8) ◽  
pp. 579-590 ◽  
Author(s):  
Gerald S. Bloomfield ◽  
Fawaz Alenezi ◽  
Felix A. Barasa ◽  
Rebecca Lumsden ◽  
Bongani M. Mayosi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Human Immunodeficiency Virus ◽  
Middle Income ◽  
Middle Income Countries ◽  
Immunodeficiency Virus ◽  
Low And Middle Income

scholarly journals Use of Contraceptives among Adolescents: What Does Global Evidence Show and How Can Nepal Learn?

2021 ◽  
Vol 18 (4) ◽  
pp. 588-595
Author(s):  
Dirgha Raj Shrestha ◽  
Rajendra Bhadra ◽  
Ganesh Dangal
Keyword(s):  
Adolescent Mothers ◽  
Unmet Need ◽  
Evidence Based ◽  
Middle Income ◽  
Evidence Based Practices ◽  
Major Health ◽  
Middle Income Countries ◽  
Increasing Demand ◽  
Desk Review ◽  
Global Evidence

Background: Adolescent pregnancy is a global health problem. Early pregnancies among adolescents have major health consequences for adolescent mothers and their babies. Contraceptives can prevent early pregnancy and its consequences. However, there is a low use of contraceptives among adolescents. Global evidence has shown which programmatic approaches are effective to increase the use of contraceptives among adolescents. Methods: This is not a systematic review. Desk review was done using Google Scholar and PubMed. Different policies, strategies, and reports published by agencies were also reviewed. Results: There is a low use of contraceptives and high unmet need for family planning and high adolescent fertility rate. Various studies conducted in different parts of the world have shown that there are some programmatic approaches implemented which are effective to improve the contraceptives use among adolescents. We have categorized the findings into three parts; i) delivery of services ii) increasing demand for services, and iii) creating an enabling environment. Conclusions: The use of contraceptives is low among adolescents in low- and middle-income countries including Nepal. So, the current programmatic approaches should be reviewed and the evidence-based practices implemented to bring better results. Ministry of Health and Population and partner agencies in Nepal also need to review the current programmatic approaches and implement them based on the evidence-based practices to improve contraceptives use among adolescents.Keywords: adolescents; contraceptive; evidence-based

scholarly journals Unmet need for hypercholesterolemia care in 35 low- and middle-income countries: A cross-sectional study of nationally representative surveys

PLoS Medicine ◽  
2021 ◽  
Vol 18 (10) ◽  
pp. e1003841
Author(s):  
Maja E. Marcus ◽  
Cara Ebert ◽  
Pascal Geldsetzer ◽  
Michaela Theilmann ◽  
Brice Wilfried Bicaba ◽  
...  
Keyword(s):  
Unmet Need ◽  
Medication Use ◽  
Older Age ◽  
Lipid Lowering ◽  
Middle Income ◽  
High Tc ◽  
Middle Income Countries ◽  
Comorbid Diagnosis ◽  
Nationally Representative ◽  
Diagnosis Of Hypertension

Background As the prevalence of hypercholesterolemia is increasing in low- and middle-income countries (LMICs), detailed evidence is urgently needed to guide the response of health systems to this epidemic. This study sought to quantify unmet need for hypercholesterolemia care among adults in 35 LMICs. Methods and findings We pooled individual-level data from 129,040 respondents aged 15 years and older from 35 nationally representative surveys conducted between 2009 and 2018. Hypercholesterolemia care was quantified using cascade of care analyses in the pooled sample and by region, country income group, and country. Hypercholesterolemia was defined as (i) total cholesterol (TC) ≥240 mg/dL or self-reported lipid-lowering medication use and, alternatively, as (ii) low-density lipoprotein cholesterol (LDL-C) ≥160 mg/dL or self-reported lipid-lowering medication use. Stages of the care cascade for hypercholesterolemia were defined as follows: screened (prior to the survey), aware of diagnosis, treated (lifestyle advice and/or medication), and controlled (TC <200 mg/dL or LDL-C <130 mg/dL). We further estimated how age, sex, education, body mass index (BMI), current smoking, having diabetes, and having hypertension are associated with cascade progression using modified Poisson regression models with survey fixed effects. High TC prevalence was 7.1% (95% CI: 6.8% to 7.4%), and high LDL-C prevalence was 7.5% (95% CI: 7.1% to 7.9%). The cascade analysis showed that 43% (95% CI: 40% to 45%) of study participants with high TC and 47% (95% CI: 44% to 50%) with high LDL-C ever had their cholesterol measured prior to the survey. About 31% (95% CI: 29% to 33%) and 36% (95% CI: 33% to 38%) were aware of their diagnosis; 29% (95% CI: 28% to 31%) and 33% (95% CI: 31% to 36%) were treated; 7% (95% CI: 6% to 9%) and 19% (95% CI: 18% to 21%) were controlled. We found substantial heterogeneity in cascade performance across countries and higher performances in upper-middle-income countries and the Eastern Mediterranean, Europe, and Americas. Lipid screening was significantly associated with older age, female sex, higher education, higher BMI, comorbid diagnosis of diabetes, and comorbid diagnosis of hypertension. Awareness of diagnosis was significantly associated with older age, higher BMI, comorbid diagnosis of diabetes, and comorbid diagnosis of hypertension. Lastly, treatment of hypercholesterolemia was significantly associated with comorbid hypertension and diabetes, and control of lipid measures with comorbid diabetes. The main limitations of this study are a potential recall bias in self-reported information on received health services as well as diminished comparability due to varying survey years and varying lipid guideline application across country and clinical settings. Conclusions Cascade performance was poor across all stages, indicating large unmet need for hypercholesterolemia care in this sample of LMICs—calling for greater policy and research attention toward this cardiovascular disease (CVD) risk factor and highlighting opportunities for improved prevention of CVD.

scholarly journals Estimation of unmet need for inguinal hernia repair among infants in low- and middle-income countries

2016 ◽  
Vol 82 (3) ◽  
pp. 563
Author(s):  
R. Tessler ◽  
S. Gupta ◽  
W. Stehr ◽  
E.A. Ameh ◽  
B. Nwomeh ◽  
...  
Keyword(s):  
Inguinal Hernia ◽  
Hernia Repair ◽  
Inguinal Hernia Repair ◽  
Unmet Need ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income
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