scholarly journals The haematological features and transfusion management of women who required massive transfusion for major obstetric haemorrhage in the UK: a population based study

2015 ◽  
Vol 172 (4) ◽  
pp. 616-624 ◽  
Author(s):  
Laura Green ◽  
Marian Knight ◽  
Frances Seeney ◽  
Cathy Hopkinson ◽  
Peter W. Collins ◽  
...  
2019 ◽  
Vol 50 (2) ◽  
pp. 625-633 ◽  
Author(s):  
Basmah H. Alfageh ◽  
Kenneth K. C. Man ◽  
Frank M. C. Besag ◽  
Tariq M. Alhawassi ◽  
Ian C. K. Wong ◽  
...  

Abstract Autism spectrum disorder (ASD) is a lifelong disorder. In the UK, risperidone is the only psychotropic medication approved for the management of the behavioural symptoms that may accompany autism. This is a population-based study aimed to provide an evaluation of the changing trend in the incidence and prevalence of ASD and to analyse the pattern of psychotropic medication prescribing in the UK. 20,194 patients with ASD were identified. The prevalence increased 3.3-fold from 0.109 per 100 persons in 2009 to 0.355 per 100 persons in 2016. Approximately one-third of the identified cohort was prescribed at least one psychotropic medication. Although the medications approved to manage the symptoms of ASD are limited, the prescribing of such medications is increasing.


Thorax ◽  
2013 ◽  
Vol 68 (6) ◽  
pp. 551-564 ◽  
Author(s):  
Sarah Walters ◽  
Camille Maringe ◽  
Michel P Coleman ◽  
Michael D Peake ◽  
John Butler ◽  
...  

2006 ◽  
Vol 17 (7) ◽  
pp. 1078-1085 ◽  
Author(s):  
P. N. Tasker ◽  
H. MacDonald ◽  
W. D. Fraser ◽  
D. M. Reid ◽  
S. H. Ralston ◽  
...  

2012 ◽  
Vol 140 (12) ◽  
pp. 2247-2255 ◽  
Author(s):  
N. D. McCARTHY ◽  
I. A. GILLESPIE ◽  
A. J. LAWSON ◽  
J. RICHARDSON ◽  
K. R. NEAL ◽  
...  

SUMMARYWe sought to explain seasonality and other aspects ofCampylobacter jejuniepidemiology by integrating population genetic and epidemiological analysis in a large 3-year longitudinal, two-centre, population-based study. Epidemiological information was collected for 1505 isolates, which were multilocus sequence-typed. Analyses compared pathogen population structure between areas, over time, and between clinical presentations. Pooled analysis was performed with published international datasets. Subtype association with virulence was not observed. UK sites had nearly identicalC. jejunipopulations. A clade formed by ST45 and ST283 clonal complexes showed a summer peak. This clade was common in a Finnish dataset but not in New Zealand and Australian collections, countries with less marked seasonality. The UK, New Zealand and Australian collections were otherwise similar. These findings map to knownin-vitrodifferences of this clade. This identifies a target for studies to elucidate the drivers of the summer peak in humanC. jejuniinfection.


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