Phase II study of tosedostat with cytarabine or decitabine in newly diagnosed older patients with acute myeloid leukaemia or high-risk MDS

Raya Mawad; Pamela S. Becker; Paul Hendrie; Bart Scott; Brent L. Wood; Carol Dean; Vicky Sandhu; Hans Joachim Deeg; Roland Walter; Lixia Wang; Han Myint; Jack W. Singer; Elihu Estey; John M. Pagel

doi:10.1111/bjh.13829

Phase II study of tosedostat with cytarabine or decitabine in newly diagnosed older patients with acute myeloid leukaemia or high-risk MDS

British Journal of Haematology ◽

10.1111/bjh.13829 ◽

2015 ◽

Vol 172 (2) ◽

pp. 238-245 ◽

Cited By ~ 16

Author(s):

Raya Mawad ◽

Pamela S. Becker ◽

Paul Hendrie ◽

Bart Scott ◽

Brent L. Wood ◽

...

Keyword(s):

High Risk ◽

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Phase Ii ◽

Older Patients ◽

Phase Ii Study ◽

Newly Diagnosed ◽

Acute Myeloid

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Randomized trial of two schedules of low-dose gemtuzumab ozogamicin as induction monotherapy for newly diagnosed acute myeloid leukaemia in older patients not considered candidates for intensive chemotherapy. A phase II study of the EORTC and GIMEMA leukaemia groups (AML-19)

British Journal of Haematology ◽

10.1111/j.1365-2141.2010.08095.x ◽

2010 ◽

Vol 149 (3) ◽

pp. 376-382 ◽

Cited By ~ 36

Author(s):

Sergio Amadori ◽

Stefan Suciu ◽

Dominik Selleslag ◽

Roberto Stasi ◽

Giuliana Alimena ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Randomized Trial ◽

Myeloid Leukaemia ◽

Older Patients ◽

Low Dose ◽

Phase Ii Study ◽

Gemtuzumab Ozogamicin ◽

Intensive Chemotherapy ◽

Newly Diagnosed ◽

Acute Myeloid

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Phase II study of targeted therapy with temozolomide in acute myeloid leukaemia and high-risk myelodysplastic syndrome patients pre-screened for low O6-methylguanine DNA methyltransferase expression

British Journal of Haematology ◽

10.1111/bjh.13094 ◽

2014 ◽

Vol 167 (5) ◽

pp. 664-670 ◽

Cited By ~ 11

Author(s):

Joseph M. Brandwein ◽

Jeannine Kassis ◽

Brian Leber ◽

Donna Hogge ◽

Kang Howson-Jan ◽

...

Keyword(s):

Targeted Therapy ◽

High Risk ◽

Acute Myeloid Leukaemia ◽

Myelodysplastic Syndrome ◽

Myeloid Leukaemia ◽

Phase Ii ◽

Dna Methyltransferase ◽

Phase Ii Study ◽

Methylguanine Dna Methyltransferase ◽

Acute Myeloid

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Durable graft-versus-leukaemia effects without donor lymphocyte infusions - results of a phase II study of sequential T-replete allogeneic transplantation for high-risk acute myeloid leukaemia and myelodysplasia

British Journal of Haematology ◽

10.1111/bjh.14980 ◽

2017 ◽

Vol 180 (3) ◽

pp. 346-355 ◽

Cited By ~ 3

Author(s):

Jeff K. Davies ◽

Sandra Hassan ◽

Shah-Jalal Sarker ◽

Caroline Besley ◽

Heather Oakervee ◽

...

Keyword(s):

High Risk ◽

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Phase Ii ◽

Phase Ii Study ◽

Allogeneic Transplantation ◽

Acute Myeloid ◽

Donor Lymphocyte Infusions

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Increased remissions from one course for intermediate-dose cytosine arabinoside and idarubicin in elderly acute myeloid leukaemia when combined with cladribine. A randomized population-based phase II study

British Journal of Haematology ◽

10.1046/j.1365-2141.2003.04702.x ◽

2003 ◽

Vol 123 (5) ◽

pp. 810-818 ◽

Cited By ~ 34

Author(s):

Gunnar Juliusson ◽

Martin Höglund ◽

Karin Karlsson ◽

Christina Löfgren ◽

Lars Möllgård ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Phase Ii ◽

Cytosine Arabinoside ◽

Phase Ii Study ◽

Population Based ◽

Acute Myeloid ◽

Intermediate Dose

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Idarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study

The Lancet Haematology ◽

10.1016/s2352-3026(19)30114-0 ◽

2019 ◽

Vol 6 (9) ◽

pp. e480-e488 ◽

Cited By ~ 19

Author(s):

Farhad Ravandi ◽

Rita Assi ◽

Naval Daver ◽

Christopher B Benton ◽

Tapan Kadia ◽

...

Keyword(s):

High Risk ◽

Acute Myeloid Leukaemia ◽

Myelodysplastic Syndrome ◽

Myeloid Leukaemia ◽

Phase 2 ◽

Newly Diagnosed ◽

Phase 2 Study ◽

Acute Myeloid

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Phase II study of 2-chlorodeoxyadenosine plus idarubicin for children with acute myeloid leukaemia in first relapse: a Paediatric Oncology Group study

British Journal of Haematology ◽

10.1111/j.1365-2141.2011.08976.x ◽

2011 ◽

Vol 156 (5) ◽

pp. 649-655 ◽

Cited By ~ 7

Author(s):

Stanley Chaleff ◽

Craig A. Hurwitz ◽

Myron Chang ◽

Gary Dahl ◽

Todd A. Alonzo ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Phase Ii ◽

Phase Ii Study ◽

Paediatric Oncology ◽

Oncology Group ◽

Oncology Group Study ◽

First Relapse ◽

Acute Myeloid

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A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome

Leukemia ◽

10.1038/leu.2015.244 ◽

2015 ◽

Vol 30 (2) ◽

pp. 268-273 ◽

Cited By ~ 40

Author(s):

N Daver ◽

H Kantarjian ◽

F Ravandi ◽

E Estey ◽

X Wang ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

High Risk ◽

Myelodysplastic Syndrome ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Gemtuzumab Ozogamicin ◽

Newly Diagnosed ◽

Relapsed Acute Myeloid Leukemia ◽

Acute Myeloid

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A trial for older patients with acute myeloid leukaemia and high risk myelodysplastic syndrome

http://isrctn.org/> ◽

10.1186/isrctn31682779 ◽

2013 ◽

Author(s):

Nigel Russell

Keyword(s):

High Risk ◽

Acute Myeloid Leukaemia ◽

Myelodysplastic Syndrome ◽

Myeloid Leukaemia ◽

Older Patients ◽

Acute Myeloid

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Temsirolimus, an mTOR inhibitor, in combination with lower-dose clofarabine as salvage therapy for older patients with acute myeloid leukaemia: results of a phase II GIMEMA study (AML-1107)

British Journal of Haematology ◽

10.1111/j.1365-2141.2011.08940.x ◽

2011 ◽

Vol 156 (2) ◽

pp. 205-212 ◽

Cited By ~ 52

Author(s):

Sergio Amadori ◽

Roberto Stasi ◽

Alberto M. Martelli ◽

Adriano Venditti ◽

Giovanna Meloni ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Phase Ii ◽

Salvage Therapy ◽

Older Patients ◽

Mtor Inhibitor ◽

Acute Myeloid

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Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia

British Journal of Haematology ◽

10.1111/j.1365-2141.2009.07919.x ◽

2010 ◽

Vol 148 (1) ◽

pp. 48-58 ◽

Cited By ~ 19

Author(s):

Thomas R. Chauncey ◽

Holly Gundacker ◽

Mazyar Shadman ◽

Alan F. List ◽

Shaker R. Dakhil ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Continuous Infusion ◽

Myeloid Leukaemia ◽

Phase Ii ◽

Older Patients ◽

Oncology Group ◽

Southwest Oncology Group ◽

Sequential Phase ◽

Acute Myeloid

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