A randomized, open-label, phase I/II trial to investigate the maximum tolerated dose of the Polo-like kinase inhibitor BI 2536 in elderly patients with refractory/relapsed acute myeloid leukaemia

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Carsten Müller-Tidow ◽  
Gesine Bug ◽  
Michael Lübbert ◽  
Alwin Krämer ◽  
Jürgen Krauter ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Acute Myeloid Leukaemia ◽  
Phase I ◽  
Myeloid Leukaemia ◽  
Kinase Inhibitor ◽  
Maximum Tolerated Dose ◽  
Open Label ◽  
Open Label Phase ◽  
Bi 2536 ◽  
Acute Myeloid

Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study

The Lancet ◽  
2012 ◽  
Vol 379 (9825) ◽  
pp. 1508-1516 ◽  
Author(s):  
Sylvie Castaigne ◽  
Cécile Pautas ◽  
Christine Terré ◽  
Emmanuel Raffoux ◽  
Dominique Bordessoule ◽  
...  
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
De Novo ◽  
Gemtuzumab Ozogamicin ◽  
Adult Patients ◽  
Open Label ◽  
Phase 3 ◽  
Open Label Phase ◽  
Acute Myeloid

scholarly journals A phase I trial investigating the Aurora B kinase inhibitor BI 811283 in combination with cytarabine in patients with acute myeloid leukaemia

2018 ◽  
Vol 185 (3) ◽  
pp. 583-587
Author(s):  
Hartmut Döhner ◽  
Carsten Müller‐Tidow ◽  
Michael Lübbert ◽  
Walter Fiedler ◽  
Alwin Krämer ◽  
...  
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Phase I ◽  
Myeloid Leukaemia ◽  
Phase I Trial ◽  
Kinase Inhibitor ◽  
Aurora B ◽  
Aurora B Kinase ◽  
Acute Myeloid

scholarly journals Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1–2 study

2017 ◽  
Vol 18 (8) ◽  
pp. 1061-1075 ◽  
Author(s):  
Alexander E Perl ◽  
Jessica K Altman ◽  
Jorge Cortes ◽  
Catherine Smith ◽  
Mark Litzow ◽  
...  
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Phase 1 ◽  
Selective Inhibition ◽  
Open Label ◽  
Open Label Phase ◽  
Acute Myeloid
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