scholarly journals DS27: Outcomes in wound healing after lower leg skin surgery

2021 ◽  
Vol 185 (S1) ◽  
pp. 115-116
Keyword(s):  
Wound Healing ◽  
Lower Leg ◽  
Skin Surgery

scholarly journals Effect of medial hemisoleus muscle flap on wound healing in the medial and distal thirds of the lower leg

2018 ◽  
Vol 33 (4) ◽  
pp. 501-510
Author(s):  
EMILIANO JOSÉ CANTON ◽  
MARCELO LIMA PUPO NOGUEIRA ◽  
LUCAS AUGUSTO CANTON FERREIRA ◽  
DENÍLSON MARCOS CÚRCIO JÚNIOR
Keyword(s):  
Wound Healing ◽  
Muscle Flap ◽  
Lower Leg

scholarly journals PRP :A MIRACLE FOR CHRONIC ULCERS

2020 ◽  
pp. 1-4
Author(s):  
Sahil Kanwar ◽  
Neni Agarwal
Keyword(s):  
Wound Healing ◽  
Platelet Rich Plasma ◽  
Lower Leg ◽  
Weekly Interval ◽  
Chronic Ulcers

In the recent years, the use of platelet rich plasma (PRP) has increased notably in a range of diseases and settings, such as wound healing. In this study we intend to likewise, a total of 25 patients with chronic non healing ulcers preferably on the lower leg and feet were enrolled and treated with PRP prepared from their own blood at a weekly interval for 1 month along with daily dressing. Response assessed after 1 month showed significant improvement in the ulcer symptoms and dimensions.

Soleus Flap for Lower Leg Reconstruction

2019 ◽  
pp. 873-880
Author(s):  
Jeffrey D. Friedman ◽  
Eric S. Ruff
Keyword(s):  
Wound Healing ◽  
Soft Tissue ◽  
Blood Supply ◽  
Soleus Muscle ◽  
Muscle Flap ◽  
Lower Leg ◽  
Soft Tissue Reconstruction ◽  
Posterior Tibial ◽  
Medial Head ◽  
Tissue Reconstruction

Open wounds in the middle third of the lower leg often require soft tissue reconstruction to allow for primary wound healing. The soleus muscle flap is uniquely suited for this purpose and is used primarily as a muscle flap without the accompanying overlying skin. This muscle has a blood supply that is segmental in nature, arising from multiple perforators from the posterior tibial vessels. Given that that this blood supply is primarily located in the proximal third of the leg, the soleus muscle flap is generally based proximally to allow for coverage of middle-third defects. While the muscle has a clear intermuscular septum which separates the medial head from the lateral segment, the use of a so-called hemi-soleus flap is less reliable and thus used on an infrequent basis. The soleus muscle flap can also be based distally in the leg for small distal-third defects; however, this flap can often be unreliable due to a paucity of sufficient perforators located in this area.

Endoscopic Technique for Subfascial Perforating Vein Interruption

1996 ◽  
Vol 3 (4) ◽  
pp. 414-420 ◽  
Author(s):  
Roy L. Tawes ◽  
L. Albert Wetter ◽  
George D. Hermann ◽  
Thomas J. Fogarty
Keyword(s):  
Wound Healing ◽  
Lower Leg ◽  
Minimally Invasive Techniques ◽  
Treatment Alternative ◽  
Perforating Veins ◽  
Working Space ◽  
Endoscopic Method ◽  
Considerable Morbidity ◽  
Invasive Techniques ◽  
Perforating Vein

Surgical treatment of incompetent perforating veins of the lower leg performed openly carries considerable morbidity associated with wound healing. Newer minimally invasive techniques offer an effective treatment alternative that avoids the lengthy incisions of the classical subfascial ligation techniques. The authors report a simple and quick two-port endoscopic method for clipping incompetent perforating veins of the lower leg using commonly available endoscopic instrumentation. The technique is unique in its use of a balloon dissector to rapidly establish the subfascial working space.

Vascularised and Modified Lower-Leg Rotationplasty for the Treatment of Severe Infection and Bone Loss of the Proximal Femur: A Case Report

2017 ◽  
Vol 27 (5) ◽  
pp. e11-e13
Author(s):  
Sebastian Fischer ◽  
Christoph Hirche ◽  
Volkmar G. Heppert ◽  
Paul A. Grützner ◽  
Ulrich Kneser ◽  
...  
Keyword(s):  
Wound Healing ◽  
Proximal Femur ◽  
Severe Infection ◽  
Lower Leg ◽  
Case Description ◽  
Infection Site ◽  
Inferior Epigastric Artery ◽  
Epigastric Artery ◽  
Paraplegic Patient

Case description We report a reconstructive case in a paraplegic patient, who suffers from a severe proximal femur infection. Aiming at the preservation of the capacity to remain in a seated position to operate a wheelchair, lower leg rotationplasty was considered suitable for reconstruction. Due to severe infection and subclinical femoral artery stenosis, rotationplasty was supercharged by the inferior epigastric artery. Furthermore, extensor tendons of the foot were attached to the acetabulum to facilitate stability of the neo-hip joint. Results Follow-up examination 1 year after surgery revealed no complications and a satisfied patient. Conclusions Especially in paraplegic patients, lower leg rotationplasty is a possible treatment option for severe femoral infection. Supercharging provides well-vascularised tissue to the former infection site and improves wound healing.

Wound Healing and Scar Formation on the Skin of the Chest Wall and the Lower Leg After Cardiac Bypass Surgery

2005 ◽  
Vol 13 (1) ◽  
pp. A6-A6
Author(s):  
Hajime Takahashi ◽  
Daisuke Kurata ◽  
Masaki Takeuchi ◽  
Kenji Sasaki ◽  
Motohiro Nozaki
Keyword(s):  
Wound Healing ◽  
Chest Wall ◽  
Bypass Surgery ◽  
Lower Leg ◽  
Scar Formation ◽  
Cardiac Bypass

scholarly journals Effects of aloe vera gel application on epidermal wound healing in the domestic rabbit

2016 ◽  
Vol 5 (1) ◽  
pp. 101 ◽  
Author(s):  
Olaifa Abayomi Kayode
Keyword(s):  
Wound Healing ◽  
Aloe Vera ◽  
Control Group ◽  
Connective Tissues ◽  
Protective Function ◽  
Aloe Vera Gel ◽  
Haematological Profile ◽  
Wound Healing Problems ◽  
Skin Surgery ◽  
And Control

Background: A wound is a breakdown in the protective function of the skin or loss of continuity of epithelium, with or without loss of underlying connective tissues, muscles, nerves, bones following injury to the skin, surgery, a blow, cut, chemicals, heat, cold, friction, shear force, pressure or diseases such as leg ulcers or carcinomas. A study was undertaken to determine the healing properties of Aloe vera gel on epidermal wounds in rabbits.Methods: Twelve adult rabbits were divided into two groups randomly of six each representing the treatment and control respectively. A pair of wounds measuring 2cm x 2cm each was created on the back of each rabbit lateral to the spinal cord. The wounds were treated with homogenized Aloe vera gel while the wounds on control group were treated with normal saline. Wound contraction was measured on days 5, 9 and 12 representing the inflammatory, proliferative and maturation phases of wound healing respectively. Blood samples were collected on days 0, 3, 6, 9 and 12 for analysis.Results: Animals treated with Aloe vera gel had significantly (p<0.05) faster rates of healing with shorter days of scab fall off than the control and showed significant (P<0.05) changes in the packed cell volume, mean corpuscular volume, lymphocyte and neutrophil counts.Conclusions: The study concluded that Aloe vera was effective in treating epidermal wounds in rabbits over the control. An improvement occured in haematological profile of the experimental animals and these findings will go a long way in expanding the horizon of clinical application of this plant in solving wound healing problems in both humans and other animal species.

ultrastructural process of intestinal wound healing

1995 ◽  
Vol 53 ◽  
pp. 1024-1025
Author(s):  
Rick L. Vaughn ◽  
Shailendra K. Saxena ◽  
John G. Sharp
Keyword(s):  
Wound Healing ◽  
Epithelial Cells ◽  
Smooth Muscles ◽  
Microscopic Level ◽  
Light Microscopic Level ◽  
Ileal Mucosa ◽  
Wound Model ◽  
Serosal Surface ◽  
Complex Process ◽  
Orderly Fashion

We have developed an intestinal wound model that includes surgical construction of an ileo-cecal patch to study the complex process of intestinal wound healing. This allows approximation of ileal mucosa to the cecal serosa and facilitates regeneration of ileal mucosa onto the serosal surface of the cecum. The regeneration of ileal mucosa can then be evaluated at different times. The wound model also allows us to determine the rate of intestinal regeneration for a known size of intestinal wound and can be compared in different situations (e.g. with and without EGF and Peyer’s patches).At the light microscopic level it appeared that epithelial cells involved in regeneration of ileal mucosa originated from the enlarged crypts adjacent to the intestinal wound and migrated in an orderly fashion onto the serosal surface of the cecum. The migrating epithelial cells later formed crypts and villi by the process of invagination and evagination respectively. There were also signs of proliferation of smooth muscles underneath the migratory epithelial cells.

Healing gone wrong: convergence of hemostatic pathways and liver fibrosis?

2020 ◽  
Vol 134 (16) ◽  
pp. 2189-2201
Author(s):  
Jessica P.E. Davis ◽  
Stephen H. Caldwell
Keyword(s):  
Wound Healing ◽  
Liver Disease ◽  
Hepatic Fibrosis ◽  
Cell Activation ◽  
Stellate Cell ◽  
Factor Xa ◽  
Clinical Trial Data ◽  
Chronic Liver ◽  
Healing Response ◽  
Wound Healing Response

Abstract Fibrosis results from a disordered wound healing response within the liver with activated hepatic stellate cells laying down dense, collagen-rich extracellular matrix that eventually restricts liver hepatic synthetic function and causes increased sinusoidal resistance. The end result of progressive fibrosis, cirrhosis, is associated with significant morbidity and mortality as well as tremendous economic burden. Fibrosis can be conceptualized as an aberrant wound healing response analogous to a chronic ankle sprain that is driven by chronic liver injury commonly over decades. Two unique aspects of hepatic fibrosis – the chronic nature of insult required and the liver’s unique ability to regenerate – give an opportunity for pharmacologic intervention to stop or slow the pace of fibrosis in patients early in the course of their liver disease. Two potential biologic mechanisms link together hemostasis and fibrosis: focal parenchymal extinction and direct stellate cell activation by thrombin and Factor Xa. Available translational research further supports the role of thrombosis in fibrosis. In this review, we will summarize what is known about the convergence of hemostatic changes and hepatic fibrosis in chronic liver disease and present current preclinical and clinical data exploring the relationship between the two. We will also present clinical trial data that underscores the potential use of anticoagulant therapy as an antifibrotic factor in liver disease.

Sign in / Sign up

Export Citation Format

Share Document