The Association Between Schizophrenia Spectrum Disorders and Psoriasis: a large‐scale population‐based case‐control study

2021 ◽  
Author(s):  
A.F. Carvalho ◽  
M.O. Machado ◽  
E. Mallia ◽  
X. Liu ◽  
L. Eder ◽  
...  
Keyword(s):  
Large Scale ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Scale Population ◽  
Spectrum Disorders ◽  
Control Study

scholarly journals A multinational case−control study comparing forensic and non-forensic patients with schizophrenia spectrum disorders: the EU-VIORMED project

2021 ◽  
pp. 1-11
Author(s):  
Giovanni de Girolamo ◽  
Laura Iozzino ◽  
Clarissa Ferrari ◽  
Pawel Gosek ◽  
Janusz Heitzman ◽  
...  
Keyword(s):  
Personality Disorder ◽  
Interpersonal Violence ◽  
Case Control Study ◽  
Case Control ◽  
Schizophrenia Spectrum Disorders ◽  
Forensic Patients ◽  
Schizophrenia Spectrum ◽  
History Of ◽  
Spectrum Disorders ◽  
Control Study

Abstract Background The relationship between schizophrenia and violence is complex. The aim of this multicentre case–control study was to examine and compare the characteristics of a group of forensic psychiatric patients with a schizophrenia spectrum disorders and a history of significant interpersonal violence to a group of patients with the same diagnosis but no lifetime history of interpersonal violence. Method Overall, 398 patients (221 forensic and 177 non-forensic patients) were recruited across five European Countries (Italy, Germany, Poland, Austria and the United Kingdom) and assessed using a multidimensional standardised process. Results The most common primary diagnosis in both groups was schizophrenia (76.4%), but forensic patients more often met criteria for a comorbid personality disorder, almost always antisocial personality disorder (49.1 v. 0%). The forensic patients reported lower levels of disability and better social functioning. Forensic patients were more likely to have been exposed to severe violence in childhood. Education was a protective factor against future violence as well as higher levels of disability, lower social functioning and poorer performances in cognitive processing speed tasks, perhaps as proxy markers of the negative syndrome of schizophrenia. Forensic patients were typically already known to services and in treatment at the time of their index offence, but often poorly compliant. Conclusions This study highlights the need for general services to stratify patients under their care for established violence risk factors, to monitor patients for poor compliance and to intervene promptly in order to prevent severe violent incidents in the most clinically vulnerable.

scholarly journals The Impact of Adverse Childhood Experiences on Coping Strategies in Schizophrenia Spectrum Disorders: A Case-Control Study

2021 ◽  
Vol Volume 14 ◽  
pp. 1315-1323
Author(s):  
Justyna Kasznia ◽  
Aleksandra Pytel ◽  
Bartłomiej Stańczykiewicz ◽  
Jerzy Samochowiec ◽  
Katarzyna Waszczuk ◽  
...  
Keyword(s):  
Adverse Childhood Experiences ◽  
Case Control Study ◽  
Case Control ◽  
Schizophrenia Spectrum Disorders ◽  
Childhood Experiences ◽  
Schizophrenia Spectrum ◽  
Adverse Childhood ◽  
Spectrum Disorders ◽  
The Impact ◽  
Control Study

scholarly journals Green tea drinking and risk of pancreatic cancer: A large-scale, population-based case–control study in urban Shanghai

2012 ◽  
Vol 36 (6) ◽  
pp. e354-e358 ◽  
Author(s):  
Jing Wang ◽  
Wei Zhang ◽  
Lu Sun ◽  
Herbert Yu ◽  
Quan-Xing Ni ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Green Tea ◽  
Large Scale ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Scale Population ◽  
Tea Drinking ◽  
Control Study

scholarly journals Chronic rhinosinusitis and premorbid autoimmune diseases: a population-based case–control study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Liang-Chun Shih ◽  
Hua-Hsin Hsieh ◽  
Gregory J. Tsay ◽  
Ivan T. Lee ◽  
Yung-An Tsou ◽  
...  
Keyword(s):  
Autoimmune Diseases ◽  
Chronic Rhinosinusitis ◽  
Large Scale ◽  
Case Control Study ◽  
Comparison Group ◽  
Fungal Infections ◽  
Population Based ◽  
Case Control ◽  
Research Database ◽  
Control Study

Abstract Evidence shows that chronic rhinosinusitis (CRS) is associated with prior presence of autoimmune diseases; however, large-scale population-based studies in the literature are limited. We conducted a population-based case–control study investigating the association between CRS and premorbid autoimmune diseases by using the National Health Insurance Research Database in Taiwan. The CRS group included adult patients newly diagnosed with CRS between 2001 and 2013. The date of diagnosis was defined as the index date. The comparison group included individuals without CRS, with 1:4 frequency matching for gender, age, and index year. Premorbid diseases were forward traced to 1996. Univariate and multivariate logistic regression was performed to estimate odds ratios (ORs) and 95% confidence intervals. The CRS group consisted of 30,611 patients, and the comparison group consisted of 122,444 individuals. Patients with CRS had a higher significant association with premorbid autoimmune diseases (adjusted OR 1.39 [1.28–1.50]). Specifically, patients with CRS had a higher significant association with ankylosing spondylitis, polymyositis, psoriasis, rheumatoid arthritis, sicca syndrome, and systemic lupus erythematosus (adjusted OR 1.49 [1.34–1.67], 3.47 [1.12–10.8], 1.22 [1.04–1.43], 1.60 [1.31–1.96], 2.10 [1.63–2.72], and 1.69 [1.26–2.25]). In subgroup analysis, CRS with and without nasal polyps demonstrated a significant association with premorbid autoimmune diseases (adjusted OR 1.34 [1.14–1.58] and 1.50 [1.38–1.62]). In addition, CRS with fungal and non-fungal infections also demonstrated a significant association with premorbid autoimmune diseases (adjusted OR 2.02 [1.72–2.49] and 1.39 [1.28–1.51]). In conclusion, a significant association between CRS and premorbid autoimmune diseases has been identified. These underlying mechanisms need further investigation.

scholarly journals Age-related macular degeneration and premorbid allergic diseases: a population-based case–control study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yi-Chen Shen ◽  
Ning-Yi Hsia ◽  
Wan-Hua Wu ◽  
Cheng-Li Lin ◽  
Te-Chun Shen ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Large Scale ◽  
Case Control Study ◽  
Allergic Diseases ◽  
Population Based ◽  
Case Control ◽  
Age Related Macular Degeneration ◽  
Eligibility Criteria ◽  
Age Related ◽  
Control Study

AbstractEvidence indicates that age-related macular degeneration (AMD) is associated with the prior presence of allergic diseases; however, large-scale studies in the literature are limited. A case–control study was conducted to describe the relationship between premorbid allergic diseases and AMD using Taiwan’s National Health Insurance database. Eligibility criteria for inclusion of new adult AMD cases from 2000 to 2013 were set up. We defined the year of diagnosis as the index year. Age-, gender-, index year- matched controls who were drawn from the same database. The case control ratio was 1:4. For all participants, all premorbid conditions staring 1996 to index year were documented. Binary logistic regression was used to describe factors related to AMD occurrence. The AMD group consisted of 10,911 patients, and the comparison group consisted of 43,644 individuals. Patients with AMD showed significant associations with premorbid allergic diseases (aOR 1.54, 95% CI 1.47–1.61), specifically with allergic conjunctivitis (aOR 2.07, 95% CI 1.94–2.20), allergic rhinitis (aOR 1.32, 95% CI 1.25–1.39), asthma (aOR 0.99, 95% CI 0.93–1.06), and atopic dermatitis (aOR 1.04, 95% CI 0.94–1.17). Further analyses indicated that patients with more concurrent allergic diseases have higher associations with AMD than those with fewer concurrent diseases. Patients with more annual medical visits for their allergic diseases also showed higher associations with AMD than those with fewer visits. AMD is significantly associated with premorbid allergic diseases. The underlying mechanisms must be further investigated.

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