Conceptual, statistical and clinical interpretation of results from: Cryosurgery combined with topical interventions for actinic keratosis: reply from the authors

2019 ◽  
Vol 181 (2) ◽  
pp. 424-425
Author(s):  
M.V. Heppt ◽  
T. Steeb ◽  
C. Berking
Keyword(s):  
Actinic Keratosis ◽  
Clinical Interpretation ◽  
Interpretation Of Results

Potentiometric methods in routine sodium and potassium measurements

2017 ◽  
Vol 53 (3) ◽  
pp. 185-190
Author(s):  
Ewelina Kmin ◽  
Dagna Bobilewicz
Keyword(s):  
Indirect Method ◽  
Clinical Interpretation ◽  
The Real ◽  
Stable Particles ◽  
Sodium And Potassium ◽  
Interpretation Of Results

Because of important role of sodium and potassium in maintenance of homeostasis the interpretation of their concentration should require special attention. In routine two potentiometric methods are used; direct (undiluted samples) and indirect (diluted samples). Results obtained by indirect method reflect the real status in case of physiological proportion of plasma water and stable particles, otherwise (lipemia, hiperproteinemia, alcoholemia) the results are falsely decreased leading particularly to pseudohiponatremia and pseudonormonatremia, what should be considered in clinical interpretation of results.

Modified erythrocyte uroporphyrinogen I synthase assay, and its clinical interpretation.

1978 ◽  
Vol 24 (10) ◽  
pp. 1751-1754 ◽  
Author(s):  
M W Piepkorn ◽  
P Hamernyik ◽  
R F Labbé
Keyword(s):  
Diagnostic Test ◽  
Young Women ◽  
Aminolevulinic Acid ◽  
Acute Intermittent Porphyria ◽  
Maximum Activity ◽  
Clinical Interpretation ◽  
Interpretation Of Results

Abstract Assay of erythrocyte uroporphyrinogen I synthase is an accepted diagnostic test for acute intermittent porphyria, particularly in those individuals who are asymptomatic or in whom the disease is not biochemically manifested by excretion of excess porphyrin precursor. The assay described is based upon a coupled-enzyme procedure in which added delta-aminolevulinic acid and its dehydratase present in erythrocytes are used to generate porphobilinogen as substrate for uroporphyrinogen synthase. Zinc and dithiothreitol are added with preincubation to give maximum activity and reproducibility. These agents also prevent inhibition by lead. Healthy young women had a mean activity of 40 nmol of porphyrin formed per milliliter of erythrocytes per hour, men and activity of 38 nmol/ml/h. Preparation of control specimens is described. This assay gave within-day CVs ranging from 1.9 to 2.8%. Precautions in interpretation of results are discussed.

Prevalence of solar damage and actinic keratosis in a Merseyside population: reply from authors

2001 ◽  
Vol 144 (2) ◽  
pp. 437-438
Author(s):  
A.A. Memon ◽  
J.A. Tomenson ◽  
J. Bothwell ◽  
P.S. Friedmann
Keyword(s):  
Actinic Keratosis
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