Assessing effectiveness in acne clinical trials: steps towards a core outcome measure set

2019 ◽  
Vol 181 (4) ◽  
pp. 700-706 ◽  
Author(s):  
D.M. Thiboutot ◽  
A.M. Layton ◽  
M.‐M. Chren ◽  
E.A. Eady ◽  
J. Tan
Keyword(s):  
Clinical Trials ◽  
Outcome Measure ◽  
Core Outcome ◽  
Core Outcome Measure

scholarly journals PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials

2018 ◽  
Vol 46 (8) ◽  
pp. 990-995 ◽  
Author(s):  
Ana-Maria Orbai ◽  
Richard Holland ◽  
Ying Ying Leung ◽  
William Tillett ◽  
Niti Goel ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Psoriatic Arthritis ◽  
Outcome Measure ◽  
Core Outcome ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Core Outcome Measure ◽  
Specific Health

Objective.The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and Outcome Measures in Rheumatology (OMERACT) psoriatic arthritis (PsA) working group is developing a Core Outcome Measurement Set for PsA clinical trials [randomized controlled trials (RCT) and longitudinal observational studies (LOS)] using the OMERACT Filter 2.1 instrument selection algorithm. Our objective was to assess the Psoriatic Arthritis Impact of Disease questionnaire (PsAID12) for the measurement of the core domain PsA-specific health-related quality of life (HRQOL).Methods.PsAID12 measurement property evidence gathered in a systematic literature review, and additional analyses conducted in LOS, were used to inform a consensus process. Analyses that had not been published were independently reviewed by the OMERACT technical advisory group. Data and process were presented, discussed in breakout groups, and voted on at the OMERACT conference (Terrigal, Australia, May 2018).Results.PsAID12 fulfilled the green (good to go) OMERACT standards for domain match, feasibility, reliability, and construct/longitudinal construct validity. Discrimination and thresholds of meaning were amber (caution but good enough to go forward). The overall working group recommendation was amber/provisional endorsement of PsAID12 for measuring PsA-specific HRQOL in RCT and LOS. Of 96 participants who voted at the PsA OMERACT workshop, 87.5% (84) voted “yes” to endorse this recommendation; 14 of the 96 were patient research partners (PRP) and 93% of them (13) voted “yes”; 82 participants were not PRP and 87% of them (71) voted “yes.”Conclusion.At OMERACT 2018, PsAID12 was the first patient-reported outcome measure provisionally endorsed as a core outcome measure for disease-specific HRQOL in PsA clinical trials. PsAID12 discrimination and improvement thresholds will be studied in future RCT.

scholarly journals Establishing a Core Outcome Measure for Graft Health

2018 ◽  
Vol 102 (8) ◽  
pp. 1358-1366 ◽  
Author(s):  
Allison Tong ◽  
Benedicte Sautenet ◽  
Emilio D. Poggio ◽  
Krista L. Lentine ◽  
Rainer Oberbauer ◽  
...  
Keyword(s):  
Outcome Measure ◽  
Core Outcome ◽  
Core Outcome Measure

scholarly journals SP597DEVELOPING A CORE OUTCOME MEASURE FOR VASCULAR ACCESS FOR TRIALS IN HAEMODIALYSIS: AN INTERNATIONAL MULTISTAKEHOLDER CONSENSUS WORKSHOP

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii336-iii336
Author(s):  
Andrea Viecelli ◽  
Allison Tong ◽  
Angela Ju ◽  
Bénédicte Sautenet ◽  
Braden Manns ◽  
...  
Keyword(s):  
Vascular Access ◽  
Outcome Measure ◽  
Core Outcome ◽  
Core Outcome Measure

Establishing a Core Outcome Measure for Life Participation

2018 ◽  
Vol 102 ◽  
pp. S562
Author(s):  
Angela Ju ◽  
Michelle A Josephson ◽  
Sheila Jowsey-Gregoire ◽  
Jane Tan ◽  
Quinetta Taylor ◽  
...  
Keyword(s):  
Outcome Measure ◽  
Core Outcome ◽  
Core Outcome Measure

Effect of adding interferential current stimulation to exercise on outcomes in primary care patients with chronic neck pain: a randomized controlled trial

2019 ◽  
Vol 33 (9) ◽  
pp. 1458-1467
Author(s):  
Manuel Albornoz-Cabello ◽  
José Manuel Pérez-Mármol ◽  
Cristo Jesus Barrios Quinta ◽  
Guillermo A Matarán-Peñarrocha ◽  
Adelaida María Castro-Sánchez ◽  
...  
Keyword(s):  
Neck Pain ◽  
Analogue Scale ◽  
Outcome Measure ◽  
Controlled Trial ◽  
Neck Disability Index ◽  
Core Outcome ◽  
Randomized Controlled ◽  
Interferential Current ◽  
Core Outcome Measure ◽  
Neck Disability

Objective: To evaluate the effect of adding interferential current stimulation to exercise on pain, disability, psychological status and range of motion in patients with neck pain. Design: A single-blinded randomized controlled trial. Setting: Primary care physiotherapy units. Subjects: A total of 84 patients diagnosed with non-specific mechanical neck pain. This sample was divided into two groups randomly: experimental ( n = 42) versus control group ( n = 42). Interventions: Patients in both groups had a supervised therapeutic exercise programme, with the experimental group having additional interferential current stimulation treatment. Main measures: The main measures used were intensity of neck pain according to the Visual Analogue Scale; the degree of disability according to the Neck Disability Index and the CORE Outcome Measure; anxiety and depression levels according to the Goldberg scale; apprehension as measured by the Personal Psychological Apprehension scale; and the range of motion of the cervical spine. The sample was evaluated at baseline and posttreatment (10 sessions/two weeks). Results: Statistically significant differences between groups at posttreatment were observed for Visual Analogue Scale (2.73 ± 1.24 vs 4.99 ± 1.56), Neck Disability Index scores (10.60 ± 4.77 vs 18.45 ± 9.04), CORE Outcome Measure scores (19.18 ± 9.99 vs 35.12 ± 13.36), Goldberg total score (6.17 ± 4.27 vs 7.90 ± 4.87), Goldberg Anxiety subscale, Personal Psychological Apprehension Scale scores (28.17 ± 9.61 vs 26.29 ± 11.14) and active and passive right rotation. Conclusions: Adding interferential current stimulation to exercise resulted in better immediate outcome across a range of measures.

scholarly journals SUN-096 STANDARDIZED OUTCOMES IN NEPHROLOGY-HEMODIALYSIS (SONG-HD): DEVELOPING A CORE OUTCOME MEASURE FOR FATIGUE IN HEMODIALYSIS

2019 ◽  
Vol 4 (7) ◽  
pp. S196
Author(s):  
A. JU ◽  
M. Unruh ◽  
C. Wilkie ◽  
G. Obrador ◽  
D. O'Donoghue ◽  
...  
Keyword(s):  
Outcome Measure ◽  
Core Outcome ◽  
Core Outcome Measure

Evaluation of the Core Outcome Measure in Whiplash

Spine ◽  
2007 ◽  
Vol 32 (6) ◽  
pp. 696-702 ◽  
Author(s):  
Trudy J. Rebbeck ◽  
Kathryn M. Refshauge ◽  
Christopher G. Maher ◽  
Mark Stewart
Keyword(s):  
Outcome Measure ◽  
Core Outcome ◽  
The Core ◽  
Core Outcome Measure

scholarly journals Establishing a Core Outcome Measure for Life Participation

2019 ◽  
Vol 103 (6) ◽  
pp. 1199-1205 ◽  
Author(s):  
Angela Ju ◽  
Michelle A. Josephson ◽  
Zeeshan Butt ◽  
Sheila Jowsey-Gregoire ◽  
Jane Tan ◽  
...  
Keyword(s):  
Outcome Measure ◽  
Core Outcome ◽  
Core Outcome Measure

Core Outcome Measure Index for low back patients: do we miss anxiety and depression?

2015 ◽  
Vol 25 (1) ◽  
pp. 265-274 ◽  
Author(s):  
C. Cedraschi ◽  
◽  
M. Marty ◽  
D. S. Courvoisier ◽  
V. Foltz ◽  
...  
Keyword(s):  
Outcome Measure ◽  
Anxiety And Depression ◽  
Core Outcome ◽  
Low Back ◽  
Core Outcome Measure Index ◽  
Core Outcome Measure ◽  
Measure Index
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