scholarly journals Differential effects of secukinumab vs. ustekinumab for treatment of psoriasis on quality of life, work productivity and activity impairment: a structural equation modelling analysis

2018 ◽  
Vol 178 (6) ◽  
pp. 1297-1307 ◽  
Author(s):  
D.E. Stull ◽  
C.E.M. Griffiths ◽  
I. Gilloteau ◽  
Y. Zhao ◽  
A. Guana ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Structural Equation Modelling ◽  
Structural Equation ◽  
Work Productivity ◽  
Activity Impairment ◽  
Differential Effects ◽  
Equation Modelling ◽  
Modelling Analysis ◽  
Life Work

scholarly journals THU0632-HPR DETERMINANTS OF HAPPINESS AND QUALITY OF LIFE IN PEOPLE WITH SYSTEMIC SCLEROSIS: A STRUCTURAL EQUATION MODELLING APPROACH

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 561.1-561
Author(s):  
T. Santiago ◽  
E. Santos ◽  
A. C. Duarte ◽  
P. Martins ◽  
M. Sousa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systemic Sclerosis ◽  
Disease Activity ◽  
Personality Traits ◽  
Structural Equation Modelling ◽  
Structural Equation ◽  
Effective Control ◽  
Equation Modelling ◽  
Disease Impact

Background:In recent years more attention has been given to patients reported outcomes (PROs). Systemic sclerosis (SSc) is no exception. As there is no effective treatment or cure to SSc, it is important to recognize the relevance to patients of the different features of the disease to improve quality and enjoyment of life: the ultimate targets of therapy. Remarkably lacking in PROs is the evaluation of the overall perspective of subjective well being, equivalent to ‘happiness’ or “positive psychological dimensions”.Objectives:To examine the determinants of happiness and quality of life (QoL) in patients with SSc with emphasis on disease activity, disease impact and personality traits.Methods:This is an observational, cross-sectional and multicenter study from six rheumatology clinics in Portugal. A total of 113 patients with SSc with a complete set of data on disease activity, disease impact, personality, quality of life and happiness were included.Structural equation modelling (latent variable structural model) was used to estimate the association between the variables using a maximum likelihood estimation with Satorra-Bentler’s correction and performed with STATA® 15.0. Two hypotheses were pursued: H1 – Disease activity and impact of disease are negatively associated to overall QoL and happiness; H2 – ‘Positive’ personality traits are related to happiness both directly and indirectly through perceived disease impact.Results:Results obtained in the structural equation measurement model indicated a good fit [χ2/df=1.44; CFI=0.93; TLI=0.90; RMSEA=0.06] and supported all driving hypotheses (Figure 1). Happiness was positively related to ‘positive’ personality (β=0.45, p=0.01) and, to a lesser extent, negatively related with impact of disease (β=-0.32; p=0.01). This impact, in turn, was positively related to EUSTAR activity score (β=0.37; p<0.001) and mitigated by ‘positive’ personality traits (β=-0.57; p<0.001). Impact of disease had a much stronger relation with QoL than with happiness (β=-0.78, p<0.001). Quality of life and happiness had no statistically significant relationship.Conclusion:Optimization of Qol and happiness in people with SSc requires effective control of the disease process. Personality and its effects upon the patient´s perception of the disease impact, seems to play a pivotal mediating role in these relations and should deserve paramount attention if happiness and enjoyment of life is taken as the ultimate goal of health care.Disclosure of Interests:Tânia Santiago: None declared, Eduardo Santos: None declared, Ana Catarina Duarte: None declared, Patrícia Martins: None declared, Marlene Sousa: None declared, Franscisca Guimarães: None declared, Soraia Azevedo: None declared, Raquel Ferreira: None declared, Miguel Guerra: None declared, Ana Cordeiro Consultant of: Ana Cordeiro has acted as a consultant for Roche, Speakers bureau: Ana Cordeiro has received speaker fees from Boehringer Ingelheim, Lilly, and Vitoria, Inês Cordeiro: None declared, Sofia Pimenta: None declared, Patrícia Pinto: None declared, Maria Joao Salvador: None declared, José Antonio P. da Silva Grant/research support from: Pfizer, Abbvie, Consultant of: Pfizer, AbbVie, Roche, Lilly, Novartis

scholarly journals Mediating Role of Quality of Life in the Relationship between Prison Climate and Life Satisfaction

2021 ◽  
Vol 2 (3) ◽  
pp. 41-48
Author(s):  
Mohd Norbayusri Baharudin ◽  
Mahadzirah Mohamad ◽  
Fazida Karim
Keyword(s):  
Quality Of Life ◽  
Life Satisfaction ◽  
Drug Abuse ◽  
Structural Equation Modelling ◽  
Structural Equation ◽  
Mediating Role ◽  
Equation Modelling ◽  
The Relationship

This study emphasises the importance of Quality of Life (QoL) as a bridge between prison climate and life satisfaction among Malaysian drug-abuse inmates. The respondents are given a self-administered assessment randomly selected from the list of drug-abuse inmates in a Malaysian prison. The Structural Equation Modelling in IBM-SPSS-AMOS 25.0 is applied to model and calculate the inter-relationships among the constructs in the study. The results show that QoL significantly influences drug abuse inmates' prison climate and life satisfaction and partially mediates the relation between prison climate and life satisfaction among Malaysian drug-abuse inmates. QoL is essential to fulfil drug-abuse inmates' life satisfaction during imprisonment and achieve a better life in the community after being released from prison. Hence, practical contributions are proposed to the Malaysian Prison Department for designing appropriate policies and strategies to improve prison climate and QoL for achieving drug-abuse inmates' life satisfaction since Malaysian life satisfaction has become the government's priority in the 12th Malaysia Plan (2021-2025). 

scholarly journals A Structural Equation Model of Improvement in Quality of Life in a Community-Based Development Projects in Nigeria

2016 ◽  
Vol 1 (4) ◽  
pp. 23 ◽  
Author(s):  
Zayyanu Muhammad ◽  
Zungwenen Jonathan ◽  
Foziah Johar ◽  
Rafee M Majid
Keyword(s):  
Quality Of Life ◽  
Structural Equation Modelling ◽  
Structural Equation ◽  
Poverty Reduction ◽  
Publishing House ◽  
Development Projects ◽  
Poverty Level ◽  
Community Based ◽  
Equation Modelling

The lingering problem of poverty has prompted many countries to adopt community-based development strategy towards improving the Quality of Life (QoL) of their citizens. Numerous studies have focused on assessing QoL by measuring the manifested (measured) variables and ignored the significant contribution of some “latent” factors. Using Structural Equation Modelling (SEM), this paper investigated the factors that influence improvement in the QoL in a Community-based Poverty Reduction Project (CPRP) in Nigeria. The model indicates that the measured variables cause only 36% (R2 = 0.36) of the reduction in poverty level of the project beneficiaries. This finding implies that there are other “hidden” factors responsible for the improvement in the quality of life.© 2016. The Authors. Published for AMER ABRA by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.Keywords: Quality of Life, Community-based Development Projects, Poverty Reduction, Structural Equation Modelling

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