Alcohol intake and risk of nonmelanoma skin cancer: a systematic review and dose–response meta‐analysis

2017 ◽  
Vol 177 (3) ◽  
pp. 696-707 ◽  
Author(s):  
H. Yen ◽  
A. Dhana ◽  
J.‐P. Okhovat ◽  
A. Qureshi ◽  
N. Keum ◽  
...  
Keyword(s):  
Systematic Review ◽  
Skin Cancer ◽  
Dose Response ◽  
Alcohol Intake ◽  
Meta Analysis ◽  
Nonmelanoma Skin Cancer

scholarly journals Alcohol and the risk of pneumonia: a systematic review and meta-analysis

BMJ Open ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. e022344 ◽  
Author(s):  
Evangelia Simou ◽  
John Britton ◽  
Jo Leonardi-Bee
Keyword(s):  
Systematic Review ◽  
Alcohol Consumption ◽  
Dose Response ◽  
Alcohol Intake ◽  
Meta Analysis ◽  
Community Acquired Pneumonia ◽  
Response Analysis ◽  
Higher Alcohol ◽  
Increased Risk ◽  
Study Heterogeneity

ObjectiveA systematic review and meta-analysis to estimate the magnitude of the association between alcohol consumption and the risk of community-acquired pneumonia (CAP) in adults was undertaken.DesignSystematic review and meta-analysis.MethodsComprehensive searches of Medline, Embase and Web of Science were carried out to identify comparative studies of the association between alcohol intake and CAP between 1985 and 2017. Reference lists were also screened. A random-effects meta-analysis was used to estimate pooled effect sizes. A dose–response meta-analysis was also performed.ResultsWe found 17 papers eligible for inclusion in the review, of which 14 provided results which could be pooled. Meta-analysis of these 14 studies identified an 83% increased risk of CAP among people who consumed alcohol or in higher amounts, relative to those who consumed no or lower amounts of alcohol, respectively (relative risk=1.83, 95% CI 1.30 to 2.57). There was substantial between-study heterogeneity, which was attributable in part to differences in study continent, adjustment for confounders and pneumonia diagnosis (clinical vs death). Dose–response analysis found that for every 10–20 g higher alcohol intake per day, there was an 8% increase in the risk of CAP.ConclusionsThe findings suggest that alcohol consumption increases the risk of CAP. Therefore, strengthening policies to reduce alcohol intake would be likely to reduce the incidence of CAP.

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