Procollagen‐3  N ‐terminal peptide measurements for the detection of liver fibrosis in methotrexate‐treated patients with psoriasis: daily practice use and clinical implications

2017 ◽  
Vol 177 (5) ◽  
pp. 1454-1457 ◽  
Author(s):  
J.M.P.A. Reek ◽  
S.P. Menting ◽  
W.W.L. Janssen ◽  
R. Dhaliwal ◽  
A.C. Heijboer ◽  
...  
2017 ◽  
Vol 66 (1) ◽  
pp. S240 ◽  
Author(s):  
F. Bende ◽  
I. Sporea ◽  
A. Popescu ◽  
R. Sirli ◽  
M. Danila ◽  
...  

2020 ◽  
Vol 10 (4) ◽  
pp. 1775-1778
Author(s):  
Anouk Tosserams ◽  
Maarten J. Nijkrake ◽  
Ingrid H.W.M. Sturkenboom ◽  
Bastiaan R. Bloem ◽  
Jorik Nonnekes

Compensation strategies are an essential part of managing gait impairments in people with Parkinson’s disease (PD). We conducted an online survey among 320 healthcare professionals with specific expertise in PD management, to evaluate their knowledge of compensation strategies for gait impairments in people with PD, and whether they applied these in daily practice. Only 35% of professionals was aware of all categories of compensation strategies. Importantly, just 23% actually applied all seven available categories of strategies when treating people with PD in clinical practice. We discuss the clinical implications, and provide recommendations to overcome this knowledge gap.


2018 ◽  
Vol 27 (150) ◽  
pp. 180079 ◽  
Author(s):  
Onno M. Mets ◽  
Cornelia M. Schaefer-Prokop ◽  
Pim A. de Jong

It is well known that lung cancer can manifest itself in imaging as solid and subsolid nodules or masses. However, in this era of increased computed tomography use another morphological computed tomography appearance of lung cancer is increasingly being recognised, presenting as a malignancy in relation to cystic airspaces. Despite the fact that it seems to be a relatively common finding in daily practice, literature on this entity is scarce and presumably the overall awareness is limited. This can lead to misinterpretation and delay in diagnosis and, therefore, increased awareness is urgently needed. This review aims to illustrate the imaging appearances of cyst-related primary lung malignancies, demonstrate its mimickers and potential pitfalls, and discuss the clinical implications based on the available literature and our own experience in four different hospitals.


2011 ◽  
Vol 39 (3) ◽  
pp. 23-34 ◽  
Author(s):  
Ryan Wilcox ◽  
Robert C. Pendleton ◽  
Kristi J. Smock ◽  
George M. Rodgers

Author(s):  
Jennifer Berumen ◽  
Jacopo Baglieri ◽  
Tatiana Kisseleva ◽  
Kristin Mekeel

Hepatology ◽  
2021 ◽  
Author(s):  
Yuh‐Jin Liang ◽  
Wei Teng ◽  
Chih‐Li Chen ◽  
Cheng‐Pu Sun ◽  
Rui‐Dung Teng ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e111551 ◽  
Author(s):  
Karel Dvorak ◽  
Jan Stritesky ◽  
Jaromir Petrtyl ◽  
Libor Vitek ◽  
Renata Sroubkova ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254939
Author(s):  
Philippe Halfon ◽  
Christelle Ansaldi ◽  
Guillaume Penaranda ◽  
Laurent Chiche ◽  
Patrick Dukan ◽  
...  

Background & aim Liver fibrosis screening in primary care population is a major public health issue. The FIB-4 index is a simple non-invasive fibrosis test combining age, transaminases, platelets count, developed for the diagnosis of advanced fibrosis. The aim of our study was to evaluate the interest of liver fibrosis screening using systematic calculation of FIB-4 in routine blood analysis. Methods Between December 2018 and May 2019, we conducted a prospective screening of liver fibrosis in 134 158 patients during a medical check-up including routine blood analysis. Among these patients, 29 707 had transaminases and platelets counts available and benefited from an automatic calculation of FIB-4. Results were obtained from 21 French clinical laboratories in the Bouches du Rhône region. Results Among the 29 707 patients, 2161 (7.3%) had a high risk of advanced fibrosis (FIB-4>2.67). Individual investigation of patients with FIB-4>2.67 allowed to screen 1268 (1268/2161: 58.7%) patients who were not managed for any liver disease. Conclusions This work demonstrates the interest of FIB-4 for the screening of liver fibrosis in primary care population. Although additional clinical validation study is required to determine the utility and applicability of Fib-4 to daily practice, our study strongly supports this easy-to-implement strategy using a simple Fib-4 measure resulting from the use of available routine test results.


2016 ◽  
Vol 18 (4) ◽  
pp. 481 ◽  
Author(s):  
Mariana M. Gersak ◽  
Monica Lupșor-Platon ◽  
Radu Badea ◽  
Anca Ciurea ◽  
Sorin M Dudea

Liver fibrosis scoring by liver biopsy has become a rarity in daily practice mainly because many non-invasive methods with similar accuracy have been developed. Among all ultrasound elastography imaging methods, Strain Elastography (SE) is the most widely available. Although SE is a qualitative and semi-quantitative method, there is reliable applicability for liver fibrosis estimation and multiple ways to transform SE into a quantitative method, in order to obtain a fibrosis score. The aim of this review is to briefly introduce all these methods and to offer support in choosing the best estimation method for liver fibrosis, with SE.


2021 ◽  
Vol 13 (9) ◽  
pp. 460-465
Author(s):  
Anastasios Katsourakis ◽  
Dimitrios Chytas ◽  
Eva Filo ◽  
Iosif Chatzis ◽  
Pantelis Chouridis ◽  
...  

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