Patient-reported adherence and persistence to topical treatments for actinic keratosis: a longitudinal diary study

2016 ◽  
Vol 175 (5) ◽  
pp. 1094-1096 ◽  
Author(s):  
S. Erntoft ◽  
J.M. Norlin ◽  
C. Pollard ◽  
T.L. Diepgen
Keyword(s):  
Actinic Keratosis ◽  
Diary Study ◽  
Patient Reported ◽  
Topical Treatments

scholarly journals Prospective, Randomized, Comparative Study of the Cutaneous Effects of a Topical Body Treatment Compared to a Bland Moisturizer

2021 ◽  
Author(s):  
Jean Carruthers ◽  
Gyasi Bourne ◽  
Michaela Bell ◽  
Alan Widgerow
Keyword(s):  
Patient Reported Outcomes ◽  
Skin Thickness ◽  
Skin Rejuvenation ◽  
Recoil Velocity ◽  
Thickness Skin ◽  
Patient Reported ◽  
Skin Retraction ◽  
Topical Treatments ◽  
Over Time

Abstract Background Over time human skin thins and loses elasticity, and topical treatments attempt to reverse this process. Objectives Assess the efficacy of TransFORM Body Treatment (TFB) in skin rejuvenation compared to a bland moisturizer on the extensor and volar forearms. Methods Blinded participants were given two products to apply on the designated forearms with follow-up at 4, 8 and 12 weeks. Measurements included skin thickness, photography, dermatopathology, cutaneous elasticity by two separate devices, and patient reported outcomes. All were compared to baseline. Results Change in roughness: extensor -0.09 mm for bland moisturizer and -0.26 mm for TFB (P = 0.174); volar 0.01mm for bland moisturizer and -0.23 mm for TFB (P = 0.004). Change in recoil velocity: volar -56 degree/s for bland moisturizer and -24 degree/s for TFB (p = 0.61); extensor -95 degree/s for bland moisturizer and -63 degree/s for TFB (p = 0.57). Change in retraction speed: volar -3.25 ms for bland moisturizer and -20.08 ms for TFB (p = 0.33); extensor -2.17 ms for bland moisturizer and -10.83 ms for TFB (p = 0.66). Histology: TFB showed an increase in mucopolysaccharide content, new collagen and increase in elastin fibers in the papillary dermis. Change in Rao-Goldman score: volar -0.17 for bland moisturizer and -0.33 for TFB (p = 0.25); extensor -0.08 for bland moisturizer and -0.17 for TFB (p = 0.36). Conclusions Histology showed production of new collagen and elastin. Quantification of changes using skin thickness, skin retraction speed and skin recoil velocity showed trends that agree with the visual data.

scholarly journals Topical treatments and photodynamic therapy for actinic keratosis of the face and scalp

2019 ◽  
Author(s):  
Kelly Foley ◽  
Aditya K Gupta ◽  
George Martin ◽  
John A Tweed ◽  
Elmer Villanueva ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Actinic Keratosis ◽  
The Face ◽  
Topical Treatments

Evaluation of the costs of topical treatments for actinic keratosis based on lesion response and the affected area

2018 ◽  
Vol 153 (6) ◽  
Author(s):  
Piergiacomo Calzavara-Pinton ◽  
Cristina Zane ◽  
Mariachiara Arisi ◽  
Pol-Antoine Hamon ◽  
Neda T. Tanova
Keyword(s):  
Actinic Keratosis ◽  
Affected Area ◽  
Topical Treatments

An economic evaluation of topical treatments for actinic keratosis

2009 ◽  
Vol 20 (5) ◽  
pp. 266-275 ◽  
Author(s):  
Dominic Muston ◽  
Anthony Downs ◽  
Vincent Rives
Keyword(s):  
Economic Evaluation ◽  
Actinic Keratosis ◽  
Topical Treatments

scholarly journals International Dermatology Outcome Measures (IDEOM): Report from the 2020 Annual Meeting

Dermatology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Alison H. Kohn ◽  
Afsaneh Alavi ◽  
April W. Armstrong ◽  
Folawiyo Babalola ◽  
Amit Garg ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Annual Meeting ◽  
Outcome Measures ◽  
Pyoderma Gangrenosum ◽  
Actinic Keratosis ◽  
Hidradenitis Suppurativa ◽  
Outcome Measurements ◽  
Dermatological Disease ◽  
Patient Reported ◽  
The Impact

<b><i>Background:</i></b> The International Dermatology Outcome Measures (IDEOM) initiative is a non-profit organization that aims to develop evidence-based outcome measurements to evaluate the impact of treatments for patients with dermatological disease. IDEOM includes all key stakeholders in dermatology (patient, physician, industry, insurer, and government) during the process of developing such outcome measurements. <b><i>Summary:</i></b> Here, we provide an update of IDEOM activities that were presented at the 2020 IDEOM Virtual Annual Meeting (October 23–24, 2020). During the meeting, multiple IDEOM workgroups (psoriasis, psoriatic arthritis, hidradenitis suppurativa, acne, pyoderma gangrenosum, and actinic keratosis) shared their progress to date, as well as future directions in developing and validating Patient-Reported Outcome Measures. Updates on demonstrating efficacy in clinicals trials by the US Food and Drug Administration are also summarized. <b><i>Key Messages:</i></b> In this report, we summarize the work presented by each IDEOM workgroup (psoriasis, psoriatic arthritis, hidradenitis suppurativa, acne, pyoderma gangrenosum, and actinic keratosis) at the 2020 IDEOM Virtual Annual Meeting.

scholarly journals Non-adherence to topical treatments for actinic keratosis

2013 ◽  
pp. 35 ◽  
Author(s):  
Alison Carr ◽  
Bav Shergill ◽  
Simon Zokaie
Keyword(s):  
Actinic Keratosis ◽  
Topical Treatments

scholarly journals Severe local skin reaction after the application of ingenol mebutate gel treated by photodynamic therapy: A case report

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Luca Negosanti ◽  
Rossella Sgarzani ◽  
Matteo Santoli ◽  
Massimino Negosanti ◽  
Nicoletta Banzola ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Actinic Keratosis ◽  
Aminolevulinic Acid ◽  
Severe Side Effect ◽  
Severe Reaction ◽  
Ingenol Mebutate ◽  
Local Skin ◽  
Local Skin Reaction ◽  
Patient Reported ◽  
Local Reactions

<p>Ingenol mebutate (IM) was recently introduced for the treatment of actinic keratosis (AK). It is considered a safe and effective treatment in spite of local reactions frequently reported. These reactions may consist of erythema, flaking, crusting, swelling, vesicles and erosions, and would usually spontaneously recede within 20–30 days. We reported a case of a patient affected by multiple actinic keratosis of the scalp treated with IM. The patient reported a severe reaction that was not solved in two months. We decided to treat the reaction with photodynamic therapy and aminolevulinic acid. This treatment was demonstrated to be effective in solving this severe side effect.</p>

Adherence to topical treatments for actinic keratosis

2016 ◽  
Vol 175 (5) ◽  
pp. 872-872
Author(s):  
L.A. Cardwell ◽  
S.R. Feldman
Keyword(s):  
Actinic Keratosis ◽  
Topical Treatments

Patients' perceptions of topical treatments of actinic keratosis

2013 ◽  
Vol 25 (5) ◽  
pp. 375-379 ◽  
Author(s):  
Solveig Esmann ◽  
Gregor B. E. Jemec
Keyword(s):  
Actinic Keratosis ◽  
Topical Treatments
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