Subcutaneous panniculitis-like T-cell lymphoma in children: a detailed clinicopathological description of 11 multifocal cases with a high frequency of haemophagocytic syndrome

2015 ◽  
Vol 172 (3) ◽  
pp. 793-797 ◽  
Author(s):  
I. Oschlies ◽  
I. Simonitsch-Klupp ◽  
J. Maldyk ◽  
D. Konovalov ◽  
D. Abramov ◽  
...  
Keyword(s):  
T Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Haemophagocytic Syndrome

An Unusual Case of a Splenic Gamma/Delta T-cell Lymphoma with Angiocentric Tendency and Haemophagocytic Syndrome

1996 ◽  
Vol 23 (5-6) ◽  
pp. 631-634 ◽  
Author(s):  
August Zabernigg ◽  
Falko Fend ◽  
Josef Thaler ◽  
Claus Gattringer
Keyword(s):  
T Cell ◽  
Unusual Case ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Gamma Delta ◽  
Haemophagocytic Syndrome ◽  
Gamma Delta T Cell

High frequency of Epstein?Barr virus in Chinese peripheral T-cell lymphoma

1994 ◽  
Vol 24 (2) ◽  
pp. 115-122 ◽  
Author(s):  
X.G. ZHOU ◽  
S.J. HAMILTON-DUTOIT ◽  
Q.H. YAN ◽  
G. PALLESEN
Keyword(s):  
T Cell ◽  
High Frequency ◽  
Epstein Barr Virus ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Peripheral T Cell Lymphoma ◽  
Barr Virus ◽  
Epstein Barr

High frequency of fatal haemophagocytic lymphohistiocytosis syndrome in enteropathy-associated T cell lymphoma

2012 ◽  
Vol 44 (4) ◽  
pp. 343-349 ◽  
Author(s):  
Aurelien Amiot ◽  
Matthieu Allez ◽  
Xavier Treton ◽  
Claire Fieschi ◽  
Lionel Galicier ◽  
...  
Keyword(s):  
T Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Haemophagocytic Lymphohistiocytosis

scholarly journals High Frequency of Genetic Aberrations in Enteropathy-Type T-Cell Lymphoma

2003 ◽  
Vol 83 (10) ◽  
pp. 1509-1516 ◽  
Author(s):  
Anne K Baumgärtner ◽  
Andreas Zettl ◽  
Andreas Chott ◽  
German Ott ◽  
Hans Konrad Müller-Hermelink ◽  
...  
Keyword(s):  
T Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Genetic Aberrations

Low Frequency of Epstein Barr Virus Association and High Frequency of p53 Overexpression in an Argentinean Pediatric T-Cell Lymphoma Series

2009 ◽  
Vol 12 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Paola Chabay ◽  
Elena De Matteo ◽  
Mario Lorenzetti ◽  
Anahí Vijnovich Barón ◽  
Pamela Valva ◽  
...  
Keyword(s):  
T Cell ◽  
High Frequency ◽  
Epstein Barr Virus ◽  
Cell Lymphoma ◽  
Low Frequency ◽  
T Cell Lymphoma ◽  
P53 Overexpression ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Detection of aberrant clones in nearly all cases of angioimmunoblastic lymphadenopathy with dysproteinemia-type T-cell lymphoma by combined interphase and metaphase cytogenetics

Blood ◽  
1994 ◽  
Vol 84 (8) ◽  
pp. 2640-2648 ◽  
Author(s):  
B Schlegelberger ◽  
Y Zhang ◽  
K Weber-Matthiesen ◽  
W Grote
Keyword(s):  
T Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
Single Cells ◽  
T Cell Lymphoma ◽  
Neoplastic Disease ◽  
Cell Of Origin ◽  
Interphase Cytogenetics ◽  
Angioimmunoblastic Lymphadenopathy ◽  
T Cell Lymphomas

Abstract Trisomy 3, trisomy 5, and an X additional chromosome are the most frequent chromosome aberrations in angioimmunoblastic lymphadenopathy with proteinemia (AILD)-type T-cell lymphomas. To evaluate the frequency of +3 and +X clones, fluorescence in situ hybridization studies with centromere-specific probes for chromosome 3 and X were done in 41 patients with peripheral T-cell lymphomas (PTL). With this interphase cytogenetic approach, 32 of 41 patients (78%) showed +3 clones, and 14 patients (34%) +X clones. These frequencies far exceeded those observed with metaphase cytogenetics (+3, 41%; +X, 20%). Summing up the results of metaphase and interphase cytogenetics, aberrant clones were found in 37 of 41 patients with PTL (90%) and 32 of 36 patients with AILD-type T-cell lymphoma (89%). Although AILD-type T- cell lymphoma is considered a neoplastic disease, it is an exception in that it shows a high frequency of cytogenetically unrelated clones and single cells that cannot be derived from a common cell of origin because of their completely different karyotypes. In five patients, double hybridization with centromere-specific probes for chromosomes 3 and X showed that these aberrations occurred in different cells. When the results of metaphase and interphase cytogenetics were combined, 17 of 36 patients with AILD-type T-cell lymphoma (47%) had unrelated clones. This high frequency of oligoclonal proliferations may be caused by increased genetic instability and an immune defect resulting in impaired elimination of aberrant cells.

scholarly journals Detection of aberrant clones in nearly all cases of angioimmunoblastic lymphadenopathy with dysproteinemia-type T-cell lymphoma by combined interphase and metaphase cytogenetics

Blood ◽  
1994 ◽  
Vol 84 (8) ◽  
pp. 2640-2648 ◽  
Author(s):  
B Schlegelberger ◽  
Y Zhang ◽  
K Weber-Matthiesen ◽  
W Grote
Keyword(s):  
T Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
Single Cells ◽  
T Cell Lymphoma ◽  
Neoplastic Disease ◽  
Cell Of Origin ◽  
Interphase Cytogenetics ◽  
Angioimmunoblastic Lymphadenopathy ◽  
T Cell Lymphomas

Trisomy 3, trisomy 5, and an X additional chromosome are the most frequent chromosome aberrations in angioimmunoblastic lymphadenopathy with proteinemia (AILD)-type T-cell lymphomas. To evaluate the frequency of +3 and +X clones, fluorescence in situ hybridization studies with centromere-specific probes for chromosome 3 and X were done in 41 patients with peripheral T-cell lymphomas (PTL). With this interphase cytogenetic approach, 32 of 41 patients (78%) showed +3 clones, and 14 patients (34%) +X clones. These frequencies far exceeded those observed with metaphase cytogenetics (+3, 41%; +X, 20%). Summing up the results of metaphase and interphase cytogenetics, aberrant clones were found in 37 of 41 patients with PTL (90%) and 32 of 36 patients with AILD-type T-cell lymphoma (89%). Although AILD-type T- cell lymphoma is considered a neoplastic disease, it is an exception in that it shows a high frequency of cytogenetically unrelated clones and single cells that cannot be derived from a common cell of origin because of their completely different karyotypes. In five patients, double hybridization with centromere-specific probes for chromosomes 3 and X showed that these aberrations occurred in different cells. When the results of metaphase and interphase cytogenetics were combined, 17 of 36 patients with AILD-type T-cell lymphoma (47%) had unrelated clones. This high frequency of oligoclonal proliferations may be caused by increased genetic instability and an immune defect resulting in impaired elimination of aberrant cells.

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