Latent tuberculosis infection in patients with chronic plaque psoriasis who are candidates for biological therapy

2014 ◽  
Vol 171 (4) ◽  
pp. 884-890 ◽  
Author(s):  
P. Gisondi ◽  
E. Pezzolo ◽  
G. Lo Cascio ◽  
G. Girolomoni
Keyword(s):  
Plaque Psoriasis ◽  
Biological Therapy ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection ◽  
Chronic Plaque Psoriasis

Latent tuberculosis infection in patients with chronic plaque psoriasis: evidence from the Italian Psocare Registry

2015 ◽  
Vol 172 (6) ◽  
pp. 1613-1620 ◽  
Author(s):  
P. Gisondi ◽  
S. Cazzaniga ◽  
S. Chimenti ◽  
M. Maccarone ◽  
M. Picardo ◽  
...  
Keyword(s):  
Plaque Psoriasis ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection ◽  
Chronic Plaque Psoriasis

scholarly journals QuantiFERON-TB Gold Plus Test in Diagnostics of Latent Tuberculosis Infection in Children Aged 1–14 in a Country with a Low Tuberculosis Incidence

2021 ◽  
Vol 70 (4) ◽  
Author(s):  
DAGMARA BORKOWSKA-TATAR ◽  
DAGMARA KRASIŃSKA ◽  
EWA AUGUSTYNOWICZ-KOPEĆ
Keyword(s):  
Negative Predictive Value ◽  
Predictive Value ◽  
Biological Therapy ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection ◽  
Pediatric Practice ◽  
Positive Results ◽  
Level Of Agreement

The aim of the study was to evaluate the QuantiFERON-TB Gold Plus (QFT-Plus) test usability in the identification of latent tuberculosis infection (LTBI) in children and the determination of features associated with tuberculin skin test (TST) and QFT-Plus-positive results concerning LTBI. Two-hundred thirteen children aged 1–14 were screened for LTBI due to household contact with TB, suspected TB, or were qualified for biological therapy. The objective of this study was to evaluate the QFT-Plus affectivity as a diagnostic test in the absence of a gold standard (GS) test for the diagnosis of LTBI. The children were diagnosed with QFT-Plus, TST, and culture of TB. The QFT-Plus results were analyzed depending on the children’s age, TST size, and type. In children aged 1–4, the positive predictive value of QFT-Plus was 1, the negative predictive value was 0.94, QFT-Plus sensitivity was 75%, and specificity was 100%. It was observed that in children aged 5–14 years, the level of agreement decreased to the substantial, i.e., 87.2%. Moreover, the negative predictive value was 0.83. QFT-Plus sensitivity was 64%, and specificity was 100%. Statistical analysis of QFT-Plus and TST results showed substantial and almost perfect agreements. Our study suggests that QFT-Plus is helpful in a pediatric practice showing good sensitivity and specificity for LTBI. The BCG vaccine, infections, and concomitant morbidities do not affect QFT-Plus results.

THU0363 Latent tuberculosis infection and viral hepatitis in a colombian cohort of patients with biological therapy

2013 ◽  
Vol 71 (Suppl 3) ◽  
pp. 278.3-278
Author(s):  
F. Gonzalez-Malaver ◽  
C.M. Guzman-Vergara ◽  
J.M. Bello-Gualtero ◽  
J. Varela ◽  
A.M. Mesa-Betancourt ◽  
...  
Keyword(s):  
Viral Hepatitis ◽  
Biological Therapy ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection

LATENT TUBERCULOSIS INFECTION IN CHILDREN AS A PREREQUISITE FOR THE TUBERCULOSIS DEVELOPMENT IN ADULTS

2019 ◽  
Vol 98 (5) ◽  
pp. 179-181
Author(s):  
Yu.P. Chugaev ◽  
◽  
A.I. Tsvetkov ◽  
I.A. Chernyaev ◽  
N.G. Kamaeva ◽  
...  
Keyword(s):  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection
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